Adaptive DNA-based materials for switching, sensing, and logic devices

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J. Mater. Chem., 2011, 21, 6113
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Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

H. Bauke Albada, Jan Willem de Vries, Qing Liu, Eyal Golub, Niels Klement, Andreas Herrmann and Itamar Willner

Chem. Commun., 2016, 52, 5561
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Activation of Mg2+-dependent DNAzymes based on AP site-containing triplex for specific melamine recognition

Ya Wang, Junying Zhang, Linling Zhu, Linlin Lu, Chongchong Feng, Fengyang Wang, Zhiai Xu and Wen Zhang

Analyst, 2015, 140, 7508
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Fundamental aspects of the nucleic acid i-motif structures

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RSC Adv., 2014, 4, 26956
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Catalytic nucleic acids (DNAzymes) as functional units for logic gates and computing circuits: from basic principles to practical applications

Ron Orbach, Bilha Willner and Itamar Willner

Chem. Commun., 2015, 51, 4144
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Recent applications of the combination of mesoporous silica nanoparticles with nucleic acids: development of bioresponsive devices, carriers and sensors

Rafael R. Castillo, Alejandro Baeza and María Vallet-Regí

Biomater. Sci., 2017, 5, 353
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Metal-dependent activity control of a compact-sized 8–17 DNAzyme based on metal-mediated unnatural base pairing

Yusuke Takezawa, Lingyun Hu, Takahiro Nakama and Mitsuhiko Shionoya

Chem. Commun., 2024, 60, 288
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Allosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs

Marianna Rossetti, Simona Ranallo, Andrea Idili, Giuseppe Palleschi, Alessandro Porchetta and Francesco Ricci

Chem. Sci., 2017, 8, 914
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Ion-induced DNAzyme switches

Simcha Shimron, Johann Elbaz, Anja Henning and Itamar Willner

Chem. Commun., 2010, 46, 3250
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Determination of magnesium ion in serum samples by a DNAzyme-based electrochemical biosensor

Xiaoyao Gao, Huiming Huang, Shuiying Niu, Huazhen Ye, Zhenyu Lin, Bin Qiu and Guonan Chen

Anal. Methods, 2012, 4, 947
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Switchable supramolecular catalysis using DNA-templated scaffolds

Miguel Angel Aleman Garcia, Yuwei Hu and Itamar Willner

Chem. Commun., 2016, 52, 2153
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Metalloporphyrin/G-quadruplexes: From basic properties to practical applications

Eyal Golub, Chun-Hua Lu and Itamar Willner

J. Porphyrins Phthalocyanines, 2015, 19, 65
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Stimuli‐Responsive Nucleic Acid‐Based Polyacrylamide Hydrogel‐Coated Metal–Organic Framework Nanoparticles for Controlled Drug Release

Wei‐Hai Chen, Wei‐Ching Liao, Yang Sung Sohn, Michael Fadeev, Alessandro Cecconello, Rachel Nechushtai and Itamar Willner

Adv Funct Materials, 2018, 28
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Design and application of multifunctional DNA nanocarriers for therapeutic delivery

P. Charoenphol and H. Bermudez

Acta Biomaterialia, 2014, 10, 1683
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Sharp Switching of DNAzyme Activity through the Formation of a CuII‐Mediated Carboxyimidazole Base Pair

Yusuke Takezawa, Lingyun Hu, Takahiro Nakama and Mitsuhiko Shionoya

Angew Chem Int Ed, 2020, 59, 21488
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Simple, one step and sensitive fluorescent nanoprobe for simultaneous detection of Pb2+ and Cu2+ based on pincer enzyme strand and signal amplification strategy

Xiang Li, Wen Yun, Wenlin Guo, Weilu Zhang and Lizhu Yang

Sensors and Actuators B: Chemical, 2019, 301, 127170
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From Cascaded Catalytic Nucleic Acids to Enzyme–DNA Nanostructures: Controlling Reactivity, Sensing, Logic Operations, and Assembly of Complex Structures

Fuan Wang, Chun-Hua Lu and Itamar Willner

Chem. Rev., 2014, 114, 2881
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Conditional nucleic acid sensors for highly spatial and temporal resolution of bioimaging

Qiming Rong, Mei Zhang, Lu Liu, Mengyi Xiong and Xiao-Bing Zhang

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A Photoresponsive Stiff‐Stilbene Ligand Fuels the Reversible Unfolding of G‐Quadruplex DNA

Michael P. O'Hagan, Susanta Haldar, Marta Duchi, Thomas A. A. Oliver, Adrian J. Mulholland, Juan C. Morales and M. Carmen Galan

Angew Chem Int Ed, 2019, 58, 4334
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Electroanalytical Applications of Metallic Nanoparticles and Supramolecular Nanostructures

Itamar Willner, Bilha Willner and Ran Tel‐Vered

Electroanalysis, 2011, 23, 13
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A simple and programmed DNA tweezer probes for one-step and amplified detection of UO22+

Zhengwei Xiong, Qiang Wang, Jiafeng Zhang, Wen Yun, Xingmin Wang, Xia Ha and Lizhu Yang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 229, 118017
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A Shape Memory Acrylamide/DNA Hydrogel Exhibiting Switchable Dual pH‐Responsiveness

Yuwei Hu, Chun‐Hua Lu, Weiwei Guo, Miguel Angel Aleman‐Garcia, Jiangtao Ren and Itamar Willner

Adv Funct Materials, 2015, 25, 6867
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Catalytic Nucleic Acids for Bioanalysis

Xiuhai Mao, Qian Li, Xiaolei Zuo and Chunhai Fan

ACS Appl. Bio Mater., 2020, 3, 2674
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A pH-regulated stimuli-responsive strategy for RNA-cleaving DNAzyme

Shasha Lu, Shuang Wang, Jiahui Zhao, Jian Sun and Xiurong Yang

Sci. China Chem., 2020, 63, 404
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A Photoresponsive Stiff‐Stilbene Ligand Fuels the Reversible Unfolding of G‐Quadruplex DNA

Michael P. O'Hagan, Susanta Haldar, Marta Duchi, Thomas A. A. Oliver, Adrian J. Mulholland, Juan C. Morales and M. Carmen Galan

Angewandte Chemie, 2019, 131, 4378
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Engineered Aptamer‐Organic Amphiphile Self‐Assemblies for Biomedical Applications: Progress and Challenges

Hongjie Xiong, Liu Liu, Yihan Wang, Hui Jiang and Xuemei Wang

Small, 2022, 18
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Isomerization Mechanism in Hydrazone-Based Rotary Switches: Lateral Shift, Rotation, or Tautomerization?

Shainaz M. Landge, Ekatarina Tkatchouk, Diego Benítez, Don Antoine Lanfranchi, Mourad Elhabiri, William A. Goddard and Ivan Aprahamian

J. Am. Chem. Soc., 2011, 133, 9812
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pH-controlled DNAzymes: Rational design and their applications in DNA-machinery devices

Yuqi Chen, Yanyan Song, Zhiyong He, Zijing Wang, Wenting Liu, Fuan Wang, Xiaolian Zhang and Xiang Zhou

Nano Res., 2016, 9, 3084
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Gated Mesoporous SiO2 Nanoparticles Using K+‐Stabilized G‐Quadruplexes

Zhanxia Zhang, Fuan Wang, Yang Sung Sohn, Rachel Nechushtai and Itamar Willner

Adv Funct Materials, 2014, 24, 5662
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Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

Yusuke Takezawa and Mitsuhiko Shionoya

Chemistry A European J, 2026, 32
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DNAzyme switches for molecular computation and signal amplification

Simon M. Bone, Nicole E. Lima and Alison V. Todd

Biosensors and Bioelectronics, 2015, 70, 330
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Stimuli‐Responsive DNA‐Functionalized Metal–Organic Frameworks (MOFs)

Jason S. Kahn, Lina Freage, Natalie Enkin, Miguel Angel Aleman Garcia and Itamar Willner

Advanced Materials, 2017, 29
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DNA‐Schalter: Grundlagen und Anwendungen

Fuan Wang, Xiaoqing Liu and Itamar Willner

Angewandte Chemie, 2015, 127, 1112
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Triplex DNA formation-mediated strand displacement reaction for highly sensitive fluorescent detection of melamine

Xiaojuan Liu, Ningning Xu, Panpan Gai and Feng Li

Talanta, 2018, 185, 352
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Sharp Switching of DNAzyme Activity through the Formation of a CuII‐Mediated Carboxyimidazole Base Pair

Yusuke Takezawa, Lingyun Hu, Takahiro Nakama and Mitsuhiko Shionoya

Angewandte Chemie, 2020, 132, 21672
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Single‐Molecule Visualization of the Activity of a Zn2+‐Dependent DNAzyme

Masayuki Endo, Yosuke Takeuchi, Yuki Suzuki, Tomoko Emura, Kumi Hidaka, Fuan Wang, Itamar Willner and Hiroshi Sugiyama

Angew Chem Int Ed, 2015, 54, 10550
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Research Progress in Construction and Application of Enzyme-Based DNA Logic Gates

Jia Liu, Shuang Liu, Chengye Zou, Shujuan Xu and Changjun Zhou

IEEE Trans.on Nanobioscience, 2023, 22, 245
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Chemical and structural modification of RNA-cleaving DNAzymes for efficient biosensing and biomedical applications

Qing Wang, Zeyue Wang, Yuqiu He, Bin Xiong, Yingfu Li and Fuan Wang

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A novel DNAzyme-based paper sensor for the simple visual detection of RNase H activity

Sina Zhang, Ye Xie, Yulong Li, Jiali Ren, Ting Deng and Jishan Li

Sensors and Actuators B: Chemical, 2021, 331, 129400
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A Novel DNAzyme Signal Amplification-based Colorimetric Method for RNase H Assays

Ye Xie, Sina Zhang, Ting Deng, Ke Zhang, Jiali Ren and Jishan Li

ANAL. SCI., 2021, 37, 1675
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Entropy driven circuit as an emerging molecular tool for biological sensing: A review

Yongxin Li, Zewei Luo, Chuyan Zhang, Rui Sun, Chen Zhou and Chengjun Sun

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Smart Mesoporous SiO2 Nanoparticles for the DNAzyme-Induced Multiplexed Release of Substrates

Zhanxia Zhang, Dora Balogh, Fuan Wang and Itamar Willner

J. Am. Chem. Soc., 2013, 135, 1934
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A New Method to Fabricate an Electrochemical Aptasensor to Assay Adenosine Deaminase Concentration using an Assistance DNA

Qing Huang, Xiaobing Wang and Lei Zheng

Journal of Immunoassay and Immunochemistry, 2014, 35, 344
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General Strategy to Introduce pH-Induced Allostery in DNA-Based Receptors to Achieve Controlled Release of Ligands

Alessandro Porchetta, Andrea Idili, Alexis Vallée-Bélisle and Francesco Ricci

Nano Lett., 2015, 15, 4467
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Dissipative Constitutional Dynamic Networks for Tunable Transient Responses and Catalytic Functions

Shan Wang, Liang Yue, Verena Wulf, Sivan Lilienthal and Itamar Willner

J. Am. Chem. Soc., 2020, 142, 17480
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Switchable Enzyme/DNAzyme Cascades by the Reconfiguration of DNA Nanostructures

Yuwei Hu, Fuan Wang, Chun‐Hua Lu, Julia Girsh, Eyal Golub and Itamar Willner

Chemistry A European J, 2014, 20, 16203
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DNA Assembly‐Based Stimuli‐Responsive Systems

Shasha Lu, Jianlei Shen, Chunhai Fan, Qian Li and Xiurong Yang

Advanced Science, 2021, 8
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Rational Control of the Activity of a Cu2+-Dependent DNAzyme by Re-engineering Purely Entropic Intrinsically Disordered Domains

Daniela Sorrentino, Simona Ranallo and Francesco Ricci

ACS Appl. Mater. Interfaces, 2021, 13, 9300
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Multitriggered Shape-Memory Acrylamide–DNA Hydrogels

Chun-Hua Lu, Weiwei Guo, Yuwei Hu, Xiu-Juan Qi and Itamar Willner

J. Am. Chem. Soc., 2015, 137, 15723
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The Trend of Nonenzymatic Nucleic Acid Amplification: Strategies and Diagnostic Application

Junyou Li, Ting Li, Zheng Zou and Hung-Wing Li

Precision Chemistry, 2025, 3, 187
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i-Motif based pH induced electrochemical switches

Xiaoyao Gao, Xianghui Li, Wenming Xiong, Huiming Huang, Zhenyu Lin, Bin Qiu and Guonan Chen

Electrochemistry Communications, 2012, 24, 9
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Triple functional DNA–protein conjugates: Signal probes for Pb2+ using evanescent wave-induced emission

Ruoyu Wang, Xiaohong Zhou and Hanchang Shi

Biosensors and Bioelectronics, 2015, 74, 78
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Ion‐Responsive Hemin–G‐Quadruplexes for Switchable DNAzyme and Enzyme Functions

Miguel Angel Aleman‐Garcia, Ron Orbach and Itamar Willner

Chemistry A European J, 2014, 20, 5619
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Single‐Molecule Visualization of the Activity of a Zn2+‐Dependent DNAzyme

Masayuki Endo, Yosuke Takeuchi, Yuki Suzuki, Tomoko Emura, Kumi Hidaka, Fuan Wang, Itamar Willner and Hiroshi Sugiyama

Angewandte Chemie, 2015, 127, 10696
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G‐Quadruplex‐Stimulated Optical and Electrocatalytic DNA Switches

Ruth Aizen, Eyal Golub, Alexander Trifonov, Simcha Shimron, Angelica Niazov‐Elkan and Itamar Willner

Small, 2015, 11, 3654
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A library of programmable DNAzymes that operate in a cellular environment

Maya Kahan-Hanum, Yehonatan Douek, Rivka Adar and Ehud Shapiro

Sci Rep, 2013, 3
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A dynamic, ultra-sensitive and “turn-on” strategy for fluorescent detection of uranyl based on DNAzyme and entropy-driven amplification initiated circular cleavage amplification

Wen Yun, Hong Wu, Zhehan Yang, Ruiqi Wang, Chongjun Wang, Lizhu Yang and Yongjian Tang

Analytica Chimica Acta, 2019, 1068, 104
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DNA Switches: From Principles to Applications

Fuan Wang, Xiaoqing Liu and Itamar Willner

Angew Chem Int Ed, 2015, 54, 1098
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