Anionic porphyrin-grafted porous silicon nanoparticles for photodynamic therapy

Emilie Secret; Marie Maynadier; Audrey Gallud; Magali Gary-Bobo; Arnaud Chaix; Emmanuel Belamie; Philippe Maillard; Michael J. Sailor; Marcel Garcia; Jean-Olivier Durand; Frédérique Cunin

doi:10.1039/C3CC38837A

Anionic porphyrin-grafted porous silicon nanoparticles for photodynamic therapy†‡

Emilie Secret,§^a Marie Maynadier,§^a Audrey Gallud,^b Magali Gary-Bobo,^b Arnaud Chaix,^a Emmanuel Belamie,^a Philippe Maillard,^cd Michael J. Sailor,^ea Marcel Garcia,^b Jean-Olivier Durand^ad and Frédérique Cunin*^a

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* Corresponding authors

^a Institut Charles Gerhardt Montpellier, UMR 5253 CNRS-ENSCM-UM2-UM1, Ecole Nationale Supérieure de Chimie de Montpellier, 34296 Montpellier, France
E-mail: frederique.cunin@enscm.fr
Fax: +33 04 6716 3470
Tel: +33 04 6716 3444

^b Institut des Biomolecules Max Mousseron, UMR 5247 CNRS-UM1-UM2, 15 Avenue Charles Flahault, BP 14491, 34093 Montpellier Cedex 05, France

^c Institut CURIE-Recherche, UMR 176, Bât. 112, Centre Universitaire, 91405 Orsay, France

^d CNRS, GDR 3049 Photomed, France

^e University of California, San Diego, Department of Chemistry and Biochemistry, 9500 Gilman Drive, m/c 0358, La Jolla, CA 92093-0358, USA

Abstract

Non-toxic porous silicon nanoparticles carry porphyrin covalently attached to their surface inside breast cancer cells for a more efficient photodynamic effect.

This article is part of the themed collection: Emerging Investigators 2013

Chemical Communications

Anionic porphyrin-grafted porous silicon nanoparticles for photodynamic therapy†‡

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Anionic porphyrin-grafted porous silicon nanoparticles for photodynamic therapy

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