An anti-poisoning nanosensor for in situ monitoring of intracellular endogenous hydrogen sulfide

Abstract

Intracellular H₂S plays an important regulatory role in cell metabolism. The limited sensing materials and severe sensor passivation hinder its quantification. We functionalized conductive nanowires with MoS₂ and quercetin in a large-scale manner, developed single nanowire sensors with excellent electrocatalytic and anti-poisoning performance, and achieved the accurate quantification of H₂S within single cells.