Issue 26, 2022

Introducing C2 asymmetry in chromans—a brief story

Abstract

The Trost group made notable attempts in the 1990s to synthesize several natural products such as vitamin E and its analogs, clusifoliol, rhododaurichromanic acid A, siccanin, and calanolide A and B through the palladium-catalyzed asymmetric allylic alkylation (AAA) reaction. This review highlights Prof. Trost's contributions to chroman chemistry, and specifically to the most challenging C2 asymmetry.

Graphical abstract: Introducing C2 asymmetry in chromans—a brief story

Article information

Article type
Perspective
Submitted
23 Feb 2022
Accepted
06 Jun 2022
First published
14 Jun 2022

New J. Chem., 2022,46, 12446-12455

Introducing C2 asymmetry in chromans—a brief story

S. Kundu, S. Bishi and D. Sarkar, New J. Chem., 2022, 46, 12446 DOI: 10.1039/D2NJ00944G

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