Issue 98, 2020

Cucurbiturils in nucleic acids research

Abstract

During the past ten years, the importance of cucurbiturils (CB[n]) as macrocyclic hosts in supramolecular assemblies with various types of natural and synthetic nucleic acids (NAs) has increased explosively. As a component of such systems, CB[n] macrocycles can play a wide spectrum of roles from drug and gene delivery vehicles to catalysts/inhibitors of biochemical reactions and even building blocks for NA-based materials. The aim of this highlight article is to describe the development of the CB[n] applications in nucleic acids research and to outline the current situation and perspectives of this fascinating synergistic combination of supramolecular chemistry of CB[n] and NAs.

Graphical abstract: Cucurbiturils in nucleic acids research

Article information

Article type
Highlight
Submitted
01 Okt 2020
Accepted
10 Nov 2020
First published
10 Nov 2020
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2020,56, 15360-15376

Cucurbiturils in nucleic acids research

E. Y. Chernikova and D. V. Berdnikova, Chem. Commun., 2020, 56, 15360 DOI: 10.1039/D0CC06583H

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