Issue 45, 2009

Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

Abstract

Regioselective synthesis of halohydrin esters was achieved by (1) the reaction of acyl halides with epoxides and (2) the rhodium-catalyzed three-component coupling reaction of alkyl halides, carbon monoxide, and epoxides.

Graphical abstract: Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

Supplementary files

Article information

Article type
Communication
Submitted
01 Jul 2009
Accepted
06 Okt 2009
First published
16 Okt 2009

Chem. Commun., 2009, 6970-6972

Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides and carbon monoxide

K. Nakano, S. Kodama, Y. Permana and K. Nozaki, Chem. Commun., 2009, 6970 DOI: 10.1039/B912907C

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