Issue 26, 2009

Rhodium catalyzed enantioselective cyclization of substituted imidazolesvia C–H bond activation

Abstract

The enantioselective intramolecular alkylation of substituted imidazoles with enantiomeric excesses up to 98% has been accomplished by rhodium catalyzed C–H bond functionalization with (S,S′,R,R′)TangPhos as the chiral ligand.

Graphical abstract: Rhodium catalyzed enantioselective cyclization of substituted imidazoles via C–H bond activation

Supplementary files

Article information

Article type
Communication
Submitted
11 Feb 2009
Accepted
01 Mai 2009
First published
02 Jun 2009

Chem. Commun., 2009, 3910-3912

Rhodium catalyzed enantioselective cyclization of substituted imidazoles via C–H bond activation

A. S. Tsai, R. M. Wilson, H. Harada, R. G. Bergman and J. A. Ellman, Chem. Commun., 2009, 3910 DOI: 10.1039/B902878A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements