Sustainable chemistry in pharma: Pfizer green chemistry team's perspective

Abstract

In the last few years, many pharmaceutical companies have publicly shared net zero goals aligned with the Paris Agreement in order to curb climate change and deliver greener medicines to patients. To achieve these ambitious objectives, embedding green and sustainable chemistry concepts into drug development strategies will be of high importance. Herein, we cover the approach taken by the Pfizer green chemistry team on its 25th anniversary, highlighting key areas of focus from discovery to manufacturing waste treatment within our small molecule portfolio, while encompassing metrics, new technologies and cross-industry consortium initiatives.