Effect of adenosine monophosphate on visible-light driven nicotinamide mononucleotide reduction in a system of water-soluble zinc porphyrin and colloidal rhodium nanoparticles

Abstract

NAD⁺ analogues, nicotinamide and nicotinamide mononucleotide (NMN⁺), were used to clarify the mechanism of visible-light driven selective NAD⁺ reduction to 1,4-NADH in a system of water soluble zinc tetraphenylporphyrin tetrasulfonate and colloidal rhodium nanoparticles dispersed with polyvinylpyrrolidone (Rh-PVP). As a result, it was found that nicotinamide was not reduced but NMN⁺ was reduced to the 1,4-form selectivity, the same as NAD⁺. In addition, the visible-light driven selective NMN⁺ reduction was found to be enhanced by the addition of the adenosine monophosphate part of the NAD⁺ structure.