Issue 3, 2018

Pyridinium salts: from synthesis to reactivity and applications

Abstract

Structurally diverse pyridinium salts are quite familiar structures in many natural products and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played an intriguing role in a wide range of research topics and, thus, this review aims at highlighting the pyridinium salts in terms of their synthetic routes, reactivity and their importance as pyridinium ionic liquids, as pyridinium ylides, as anti-microbial, anti-cancer, anti-malarial and anti-cholinesterase inhibitors, as well as their applications in materials science and biological issues related to gene delivery.

Graphical abstract: Pyridinium salts: from synthesis to reactivity and applications

Article information

Article type
Review Article
Submitted
15 Sep 2017
Accepted
25 Okt 2017
First published
03 Nov 2017

Org. Chem. Front., 2018,5, 453-493

Pyridinium salts: from synthesis to reactivity and applications

S. Sowmiah, J. M. S. S. Esperança, L. P. N. Rebelo and C. A. M. Afonso, Org. Chem. Front., 2018, 5, 453 DOI: 10.1039/C7QO00836H

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