Schematic of the action mechanism of Pira–Gem co-loaded mPEG-b-PLA-LA nanoparticles on a cancer cell.
A co-delivery system employing cisplatin and novel conjugated polymers is utilized to achieve synergistic chemotherapy/photothermal therapy for cancer treatment at lower drug concentrations.
Visible light responsive micellar drug delivery formulations are of notable interest for the treatment of ocular diseases given the accessibility of the eye to light transmission.
ACB and ABC triblock copolymer nanoparticles were prepared by reversible addition–fragmentation chain transfer (RAFT) dispersion polymerization using diblock copolymer macromolecular RAFT (macro-RAFT) agents with different RAFT group positions.
mPEGylated AG@mPEG-DMSN possesses excellent mucus-penetrating ability dependent on steric repulsion and significantly improved cell uptake of AG owing to surface dendritic superstructures.