Issue 12, 2018

Chirality in metal-based anticancer agents

Abstract

Chiral natural biological molecules, such as nucleic acids and proteins, guide the research of chiral compounds. Chiral metal-based drugs are currently an interesting and rapidly growing field in anticancer research. This perspective focuses on chiral metal compounds with application in cancer chemotherapy. The different chiral metal-based anticancer agents and the extent to which the chiral resolution affects their biological properties are discussed. This perspective will aid the design of new potent and efficient chiral metal-based anticancer drugs that exploit their unique properties combined with their potential selectivity toward targeted chiral biomolecules.

Graphical abstract: Chirality in metal-based anticancer agents

Article information

Article type
Perspective
Submitted
09 Jän 2018
Accepted
07 Feb 2018
First published
08 Feb 2018

Dalton Trans., 2018,47, 4017-4026

Chirality in metal-based anticancer agents

Y. Wang, H. Huang, Q. Zhang and P. Zhang, Dalton Trans., 2018, 47, 4017 DOI: 10.1039/C8DT00089A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements