Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

Xiaowan Zhang; Meirong Shan; Siying Li; Jing Zhao; Xuelei Pang; Guocheng Yang; Yuping Shan

doi:10.1039/D3CP00342F

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs†

Xiaowan Zhang,^a Meirong Shan,^a Siying Li,^a Jing Zhao,^a Xuelei Pang,^a Guocheng Yang^a and Yuping Shan

*^a

Author affiliations

* Corresponding authors

^a School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China
E-mail: shanyp@ciac.ac.cn

Abstract

Transferrin (Tf) has been effectively used to promote the cellular uptake of HAIYPRH (T7) peptide-conjugated nano-drugs. In this study, the enhancing effect of Tf on T7-decorated nano-drug transport was investigated using force tracing and nano-indentation techniques at a single-particle/cell level. Furthermore, the results were confirmed by ensemble fluorescence imaging.

This article is part of the themed collections: 2023 PCCP HOT Articles and Emerging concepts in nucleic acids: structures, functions and applications

Download options Please wait...

Supplementary files

Supplementary information PDF (1371K)

Article information

DOI: https://doi.org/10.1039/D3CP00342F
Article type: Communication
Submitted: 21 Jän 2023
Accepted: 09 Mär 2023
First published: 09 Mär 2023

Download Citation

Phys. Chem. Chem. Phys., 2023,25, 9766-9771

Permissions

Request permissions

Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

X. Zhang, M. Shan, S. Li, J. Zhao, X. Pang, G. Yang and Y. Shan, Phys. Chem. Chem. Phys., 2023, 25, 9766 DOI: 10.1039/D3CP00342F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Physical Chemistry Chemical Physics

Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

Social activity

Search articles by author

Spotlight

Advertisements