Issue 12, 2019
From the journal:

Chemical Communications

Photoenzymatic epoxidation of styrenes†

Morten M. C. H. van Schie, ORCID logo a   Caroline E. Paul, ORCID logo b   Isabel W. C. E. Arends ORCID logo c  and  Frank Hollmann ORCID logo *a  

* Corresponding authors

a Department of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629 HZ Delft, The Netherlands
E-mail: f.hollmann@tudelft.nl

b Laboratory of Organic Chemistry, Wageningen University & Research, Stippeneng 4, 6708WE Wageningen, The Netherlands

c Faculty of Science, University of Utrecht, The Netherlands

Abstract

Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH2 prosthetic group. In this contribution we provide the proof-of-concept and characterization for the direct regeneration of the styrene monooxygenase from Pseudomonas.

Graphical abstract: Photoenzymatic epoxidation of styrenes

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8CC08149B
Article type
Communication
Submitted
11 Okt 2018
Accepted
18 Dez 2018
First published
22 Jän 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2019,55, 1790-1792

Permissions

Request permissions

Photoenzymatic epoxidation of styrenes

M. M. C. H. van Schie, C. E. Paul, I. W. C. E. Arends and F. Hollmann, Chem. Commun., 2019, 55, 1790 DOI: 10.1039/C8CC08149B

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements