Issue 4, 2014

Recent advances in C–H fluorination

Abstract

Incorporation of fluorine atom(s) into organic compounds is often desirable in the discovery of new pharmaceuticals, agrochemicals, and materials. However, development of transformations to incorporate fluorine is challenging because of its highly electronegative nature. Recent advances in C–H functionalization have allowed new approaches to C–F bonds. Herein we highlight progress in C–H fluorination, which is arguably the most efficient approach to incorporate fluorine since it obviates the need of pre-functionalization of organic compounds.

Graphical abstract: Recent advances in C–H fluorination

Article information

Article type
Highlight
Submitted
20 Jän 2014
Accepted
05 Feb 2014
First published
07 Mär 2014

Org. Chem. Front., 2014,1, 434-438

Author version available

Recent advances in C–H fluorination

A. Lin, C. B. Huehls and J. Yang, Org. Chem. Front., 2014, 1, 434 DOI: 10.1039/C4QO00020J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements