Issue 100, 2021
From the journal:

Chemical Communications

Molecular recognition and photoprotection of riboflavin in water by a biomimetic host†

Hong Zhang,a   Li-Li Wang,*ab   Xin-Yu Pang, ORCID logo a   Liu-Pan Yang ORCID logo *a  and  Wei Jiang ORCID logo *a  

* Corresponding authors

a Shenzhen Grubbs Institute, Guangdong Provincial Key Laboratory of Catalysis and Department of Chemistry, Southern University of Science and Technology, Xueyuan Blvd 1088, Shenzhen, China
E-mail: yanglp@sustech.edu.cn, jiangw@sustech.edu.cn

b Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study&Department of Pharmacy and Pharmacology, University of South China, Hengyang, China
E-mail: liliwang616@163.com

Abstract

A water-soluble tetralactam macrocycle with 2,6-diethoxynaphthalene groups as side walls is able to strongly bind riboflavin (Ka >107 M−1) in water through hydrogen bonding and the hydrophobic effect. The encapsulated riboflavin can be stabilized by the host against photo-degradation under UV-vis irradiation, which may be harnessed to extend the shelf life of riboflavin.

Graphical abstract: Molecular recognition and photoprotection of riboflavin in water by a biomimetic host

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Article information

DOI
https://doi.org/10.1039/D1CC05818E
Article type
Communication
Submitted
15 Okt 2021
Accepted
23 Nov 2021
First published
27 Nov 2021

Chem. Commun., 2021,57, 13724-13727

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Molecular recognition and photoprotection of riboflavin in water by a biomimetic host

H. Zhang, L. Wang, X. Pang, L. Yang and W. Jiang, Chem. Commun., 2021, 57, 13724 DOI: 10.1039/D1CC05818E

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