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Ling Li, Cong Yang, Mengzhen Jia, Yuhao Wang, Yu Zhao, Qingyuan Li, Jun Gong, Ying He, Kun Xu, Xuebo Liu, Xuhui Chen, Jun Hu and Zhigang Liu

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DOI: 10.1039/D4FO00886C

Synergistic protective effects of β-glucan and Lactobacillus johnsonii NSP009 in ulcerative colitis

Shanshan Zhang, Yonggan Sun, Linlin Gao, Ziyi Zhang, Yongkang Yu, Dechang Xu and Shaoping Nie

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DOI: 10.1039/D5FO02391B

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Food Funct., 2025, 16, 5757
DOI: 10.1039/D5FO01854D

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Food Funct., 2025, 16, 2703
DOI: 10.1039/D4FO06234E

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Ning Li, Xinyan Han, Ming Ruan, Fei Huang, Liu Yang, Tianhao Xu, Huijun Wang, Hui Wu, Songshan Shi, Yongjun Wang, Xiaojun Wu and Shunchun Wang

Gut Microbes, 2024, 16
DOI: 10.1080/19490976.2024.2402547

Multi-omics investigation unveils the role of Eurotium cristatum fermentation in potentiating thinned young apple pomace for colitis-induced liver disorders amelioration

Jiayao Lv, Yi Wang, Lanqi Zhou, Shiyi Zhang, Wei Song, Rui Dong, Tianqi Liu, Guoze Wang and Lin Shi

Food Research International, 2025, 220, 117095
DOI: 10.1016/j.foodres.2025.117095

Multi-omics insights into anti-colitis benefits of the synbiotic and postbiotic derived from wheat bran arabinoxylan and Limosilactobacillus reuteri

Lanqi Zhou, Wei Song, Tianqi Liu, Tao Yan, Ziyan He, Weitai He, Jiayao Lv, Shiyi Zhang, Xiaoshuang Dai, Li Yuan and Lin Shi

International Journal of Biological Macromolecules, 2024, 278, 134860
DOI: 10.1016/j.ijbiomac.2024.134860

Butyrylated modification of corn starch alleviates autism-like behaviors by modulating 5-hydroxytryptamine metabolism and gut-brain neural activity

Wentian Li, Qingmin Kong, Min Guo, Linlin Wang, Peijun Tian, Jingyu Lu, Jianxin Zhao, Wei Chen and Gang Wang

Carbohydrate Polymers, 2025, 351, 123073
DOI: 10.1016/j.carbpol.2024.123073

Limosillactobacillus reuteri C501 modulates tryptophan metabolism and alleviates obesity-induced gut-adipose tissue axis metabolic disorders through AhR and Bmal1/Pparγ signaling

Shufeng Wu, Xiang Kuang, Haizhao Song, Zhigang Liu, Ling Xiong, Bo Ren, Fang Wang, Xinchun Shen and Luanfeng Wang

Food Bioscience, 2025, 73, 107653
DOI: 10.1016/j.fbio.2025.107653

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Adila Abulaiti, Huanhuan Yu, Junmei Ma, Anikezi Wuji and Honggang Chi

Ann Nutr Metab, 2025, 1
DOI: 10.1159/000549716

Microbial Metabolites and the Gut-Brain Axis in Neurological Disorders: Implications for Neuropharmacology and Therapy

Yuchen Wang and Zhang Yang

Neuropharmacology and Therapy, 2025, 2
DOI: 10.15212/npt-2025-0008

Current research progress, opportunities, and challenges of Limosillactobacillus reuteri -based probiotic dietary strategies

Luanfeng Wang, Bo Ren, Shufeng Wu, Haizhao Song, Ling Xiong, Fang Wang and Xinchun Shen

Critical Reviews in Food Science and Nutrition, 2025, 65, 3607
DOI: 10.1080/10408398.2024.2369946

Limosillactobacillus reuteri C501 ameliorates circadian metabolic disorders in mouse liver via AhR/Bmal1 signaling pathway

LuanFeng WANG, ShuFeng WU, YuTong LI, ZhiGang LIU, Fang WANG, HaiZhao SONG, Ling XIONG, Bo REN and XinChun SHEN

Sci. Sin.-Vitae, 2025, 55, 2615
DOI: 10.1360/SSV-2024-0309

Probiotics Encapsulated via Biological Macromolecule for Neurological Therapy and Functional Food: A Review

Xitong Wang, Jinhua Hu, Hanzhong Zhang and Peng Zhou

Probiotics & Antimicro. Prot., 2025, 17, 1754
DOI: 10.1007/s12602-025-10453-1

Advances in Dietary Modulation of the Intestinal Barrier: Mechanistic, Structural, and Functional Insights

Jianwei Zang, Luyao Xiao, Yibo Shi, Yimeng Kou, Kai Ma, Changliang Zhang, Xin Rui, Tao Lin and Wei Li

Comp Rev Food Sci Food Safe, 2026, 25
DOI: 10.1111/1541-4337.70383

Intergenerational effects of the microbiota on neurodevelopment: mechanisms and therapeutic perspectives

Ruo-xi Wang, Ali Afzal, Xiao-yuan Jing, Yu Zhou, Jin-xing Feng, Zu-xin Chen, De-zhi Cao and Xin-an Liu

Acta Pharmacol Sin, 2026
DOI: 10.1038/s41401-025-01693-6

Current perspectives on inulin as a functional prebiotic: mechanisms, health implications, and synbiotic preparations

Yasser Gaber, Tayf K. Al-Tarawneh, Sara Salama, Bayan A. AlShgoor, Enas Almahasnh, Forat Almaaitah and Rasha Hussein

Nutrire, 2025, 50
DOI: 10.1186/s41110-025-00373-z

Evaluation of GABA-Producing Fermented Whey Formulations: From Strain Selection to Raspberry-Enriched Beverages with Psychobiotic Potential

Mariano Del Toro-Barbosa, Tlalli Uribe-Velázquez, Alejandra Hurtado-Romero, María Fernanda Rosales-De la Cruz, Danay Carrillo-Nieves, Luis Eduardo Garcia-Amezquita and Tomás García-Cayuela

Foods, 2025, 14, 2762
DOI: 10.3390/foods14162762

Non-gene-edited neural stem cells reverse neuroinflammation and microbiota dysbiosis in a sprague-dawley rat model of autism spectrum disorder

Zhaoming Liu, Caixia Wu, Xianjie Li, Han Wang, Muhammad Majid, Rajesh Basnet and Zhiyuan Li

Transl Psychiatry, 2026
DOI: 10.1038/s41398-026-03841-w

Synbiotic Intervention with Inulin and Lactiplantibacillus plantarum LPm77 Attenuates Type 2 Diabetes via Enhanced TUDCA Metabolism and Gut–Liver Axis Modulation

Minghan Li, Jialin Guo, Jinxin Meng, Xueting Wang, Tianxu Pan, Dongyu Zhao, Hongye Li, Ruyi Gao, Ya Wang, Hechun Li, Songyang Li, Jiagan Wang, Haibin Huang, Nan Wang, Shuyuan Yu, Jiayao Guan, Mingxiao Liu, Chunfeng Wang and Guilian Yang

J. Agric. Food Chem., 2025, 73, 19442
DOI: 10.1021/acs.jafc.5c03515

The hologenome in brain health and disease

Sean W. Dooling and Mauro Costa-Mattioli

Neuron, 2026, 114, 212
DOI: 10.1016/j.neuron.2025.10.039

The Impact of Lactobacillus reuteri on Oral and Systemic Health: A Comprehensive Review of Recent Research

Zihui Liu, Qing Cao, Wenqing Wang, Bowen Wang, Yilun Yang, Cory J. Xian, Tiejun Li and Yuankun Zhai

Microorganisms, 2024, 13, 45
DOI: 10.3390/microorganisms13010045

Prebiotic Treatment During Pregnancy Prevents Social Deficits Associated with Autism Spectrum Disorder-like Behavior Induced by Maternal Immune Activation

Frederico Rogério Ferreira, Guilherme Araujo Rouvier, Lucas Hassib, Raphael de Andrade Morraye, Yago Soares Pereira da Silva, Luís Fernando Saldanha da Gama, Iuri Souza Pereira, Angelica Oliveira Gomes, Maria Julia Granero Rosa, Ana Carolina de Morais-Scussel, Greice Andreotti de Molfetta and Wilson Araujo Silva

Microorganisms, 2025, 14, 60
DOI: 10.3390/microorganisms14010060

Innovative Oat‐Based Postbiotic and Synbiotic Products: Chemical Constituents and Hepatoprotective Efficacy

Ruixue Wen, Lanqi Zhou, Wei Song, Jiayao Lv, Tianqi Liu, Haizhou Wu and Lin Shi

eFood, 2025, 6
DOI: 10.1002/efd2.70052

Oral colon-retentive inulin gels protect against radiation-induced hematopoietic and gastrointestinal injury by improving gut homeostasis

Dongdong Liu, Meng Wei, Yubao Fang, Tianyu Yuan, Yingbao Sun, Hua Xie, Wenrui Yan, Bochuan Yuan, Bo Zhuang and Yiguang Jin

International Journal of Biological Macromolecules, 2025, 292, 139199
DOI: 10.1016/j.ijbiomac.2024.139199

Gut microbiota and behavioral ontogeny in autism spectrum disorder: a pathway to therapeutic innovations

Akanksha Yadav, Manasi Tadas, Mayur Kale, Nitu Wankhede, Milind Umekar, Nandkishor Kotagale and Brijesh Taksande

Physiology & Behavior, 2025, 299, 114989
DOI: 10.1016/j.physbeh.2025.114989

Indole lactic acid derived from Akkermansia muciniphila activates the aryl hydrocarbon receptor to inhibit ferroptosis in ischemic stroke

Jiahan Wang, Yongzheng Peng, Yarui Liu, Zhuoshi Lian, Zheng Cai, Ye Chen, Haoqing He, Meilin Yang and Jie Zhao

Free Radical Biology and Medicine, 2025, 234, 113
DOI: 10.1016/j.freeradbiomed.2025.04.020

The Role of Probiotics Limosilactobacillus reuteri, Ligilactobacillus salivarius, and Lactobacillus johnsonii in Inhibziting Pathogens, Maintaining Gut Health, and Improving Disease Outcomes

Li Li, Xiangqi Qiu, Shengyong Lu, Haitao Yu, Panpan Lu, Sumei Zeng, Aihua Deng, Min Zhu, E Xu and Jin Niu

IJMS, 2026, 27, 1545
DOI: 10.3390/ijms27031545

Wheat Bran Arabinoxylan Potentiates Hepatoprotective Efficacy of Postbiotic Limosilactobacillus reuteri in Colitis Mice via a Gut–Liver Axis

Lanqi Zhou, Tianqi Liu, Shiyi Zhang, Jiayao Lv, Yi Wang, Guoze Wang, Xiaoshuang Dai, Jiahui Wang, Zhichao Zhang, Ken Cheng, Honglei Tian and Lin Shi

J. Agric. Food Chem., 2026
DOI: 10.1021/acs.jafc.5c11722

Parishin A reduces hepatic encephalopathy via gut microbiota increasing the activity of intestinal EAAT3 to reduce blood ammonia

Jin-Yue Lu, Heng-Tong Zuo, Ru Feng, Yi-Lin Chen, Meng-Liang Ye, Hui Xu, Jia-Chun Hu, Jian-Ye Song, Yi Zhao, Jing-Yue Wang, Jing-Yu Jin, Tie-Feng Yuan, Wan-Xia Wang, Yi-Fan Zhao, Yong-Mei Tu, Ling-Yu Wei, Ming-Yang Li, Bin Cong, Jian-Dong Jiang and Yan Wang

Pharmacological Research, 2025, 222, 108030
DOI: 10.1016/j.phrs.2025.108030

The alleviating effects of tryptophan metabolite indole-3-propionic acid on glycolipid metabolism disorders and cognitive dysfunction in obese mice

Chen Ding, Ying He, Zhitong Wang, Xiao Xiao, Yihang Zhao, Yuhao Wang, Xia Chen, Rui Guo, Yongbo She, Bin Wang and Zhigang Liu

Food Bioscience, 2025, 68, 106742
DOI: 10.1016/j.fbio.2025.106742

Clinical Study of Limosilactobacillus reuteri for the Treatment of Children with Chronic Tic Disorders/Tourette Syndrome: A Mid-Term Efficacy Evaluation

Yan Liang, Lin Wan, Guanglei Wang, Huimin Yan, Jing Zhang, Xinting Liu, Ziyan Zhang, Gang Zhu and Guang Yang

Neurol Ther, 2025, 14, 279
DOI: 10.1007/s40120-024-00693-8

Inulin and multispecies probiotic effects on blood, liver and kidney biochemistry and metabolic and stress-related gene expression in pigs

Adam Lepczyński, Agnieszka Herosimczyk, Małgorzata Ożgo, Aleksandra Dunisławska, Michalina Adaszyńska-Skwirzyńska, Anna Tuśnio, Elżbieta Pietrzak, Adrianna Konopka, Kamil Gawin, Ewa Święch, Elżbieta Redlarska, Sylwia Słuczanowska-Głąbowska, Marcin Taciak, Mateusz Bucław, Łukasz Struk and Marcin Barszcz

Sci Rep, 2026
DOI: 10.1038/s41598-026-43434-7

A Synbiotic of Bifidobacterium animalis subsp. lactis BB-12 and 2′-FL Alleviate Infant Diarrhea and Anxiety-like Behaviors via Gut Microbiota Modulation in an EPEC O127 Infection Model

Zhuo Liu, Wenxiu Wang, Ning Li, Jinkuan Chen, Qianxu Wang, Mengzhen Jia, Xiaorui Wang, Bo Zhang, Nan Sheng and Zhigang Liu

Nutrients, 2025, 17, 3099
DOI: 10.3390/nu17193099

Gut microbiota and brain-resident CD4+ T cells shape behavioral outcomes in autism spectrum disorder

John Chulhoon Park, Min-A Sim, Changhon Lee, Hye-Eun Park, Juhun Lee, Seung Yeon Choi, Seohyun Byun, Haeun Ko, Haena Lee, Seung Won Kim, Jaegyun Noh, Geon Park, Solji Lee, Tae-Kyung Kim and Sin-Hyeog Im

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-61544-0

Lactobacillus reuteri paradigm - How loss of a sentinel of gut-brain-metabolic health fuels modern epidemics and era of microbial restoration

Aisha Farhana

IJHS, 2025, 19, 1
DOI: 10.25259/IJHS_1_2025

Mezcal: A Review of Chemistry, Processing, and Potential Health Benefits

Sandra Victoria Ávila-Reyes, Antonio Ruperto Jiménez-Aparicio, Guiomar Melgar-Lalanne, Fernanda Sarahí Fajardo-Espinoza and Humberto Hernández-Sánchez

Foods, 2025, 14, 1408
DOI: 10.3390/foods14081408

Functional Properties of Probiotics in Food Sources

Jiajia Song

Foods, 2024, 13, 2548
DOI: 10.3390/foods13162548

Estrogenic Effect of Probiotics on Anxiety and Depression: A Narrative Review

Gilberto Uriel Rosas-Sánchez, León Jesús Germán-Ponciano, Juan Francisco Rodríguez-Landa, Herlinda Bonilla-Jaime, Ofelia Limón-Morales, Rosa Isela García-Ríos, José Luis Muñoz-Carrillo, Oscar Gutiérrez-Coronado, Paola Trinidad Villalobos-Gutiérrez and César Soria-Fregozo

IJMS, 2025, 26, 9948
DOI: 10.3390/ijms26209948

Attenuating Neurotoxicity Through Fecal Microbiota Transplant: Mechanisms and Therapeutic Potential

Nada Khairi Younis, Karar H. Alfarttoosi, Gaurav Sanghvi, R. Roopashree, Aditya Kashyap, T. Krithiga, Waam Mohammed Taher, Mariem Alwan, Mahmood Jasem Jawad and Ali M. Ali Al-Nuaimi

Mol Neurobiol, 2026, 63
DOI: 10.1007/s12035-025-05415-1

Infuence of prebiotics on childhood autism: Evidences and implications

Mariagiovanna Di Chiano and Emanuela Calò

Global Pediatrics, 2025, 14, 100295
DOI: 10.1016/j.gpeds.2025.100295