Issue 8, 2024

Liquid–liquid phase separation-inspired design of biomaterials

Abstract

Liquid–liquid phase separation (LLPS) is a crucial biological process that governs biomolecular condensation, assembly, and functionality within phase-separated aqueous environments. This phenomenon serves as a source of inspiration for the creation of artificial designs in both structured and functional biomaterials, presenting novel strategies for manipulating the structures of functional protein aggregates in a wide range of biomedical applications. This mini review summarizes my past research endeavors, offering a panoramic overview of LLPS-inspired biomaterials utilized in the design of structured materials, the development of cell mimetics, and the advancement of intelligent biomaterials.

Graphical abstract: Liquid–liquid phase separation-inspired design of biomaterials

Article information

Article type
Minireview
Submitted
08 dec 2023
Accepted
23 feb 2024
First published
26 feb 2024

Biomater. Sci., 2024,12, 1943-1949

Liquid–liquid phase separation-inspired design of biomaterials

Y. Song, Biomater. Sci., 2024, 12, 1943 DOI: 10.1039/D3BM02008H

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