Issue 2, 2019

The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

Abstract

Covering: 2006 to 2018

The application of the 6π-azaelectrocyclization of azatrienes as a key strategy for the synthesis of natural products, their analogs and related bioactive or biomedically-relevant compounds (from 2006 to date) is comprehensively reviewed. Details about reaction optimization studies, relevant reaction mechanisms and conditions are also discussed.

Graphical abstract: The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

Article information

Article type
Review Article
Submitted
08 feb 2018
First published
09 aug 2018

Nat. Prod. Rep., 2019,36, 354-401

The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

D. F. Vargas, E. L. Larghi and T. S. Kaufman, Nat. Prod. Rep., 2019, 36, 354 DOI: 10.1039/C8NP00014J

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