Issue 18, 2019

Model study on trapping of protein selenenic acids by utilizing a stable synthetic congener

Abstract

A stable primary-alkyl-substituted selenenic acid was developed as a synthetic model of selenocysteine–derived selenenic acid (Sec–SeOH) by taking advantage of a huge cavity-shaped substituent. The primary-alkyl model compound was successfully applied to model studies on the trapping reaction of protein Sec–SeOH generated in the active site of selenoenzymes with several reagents.

Graphical abstract: Model study on trapping of protein selenenic acids by utilizing a stable synthetic congener

Supplementary files

Article information

Article type
Letter
Submitted
28 feb 2019
Accepted
18 mar 2019
First published
18 mar 2019

New J. Chem., 2019,43, 6830-6833

Model study on trapping of protein selenenic acids by utilizing a stable synthetic congener

S. Sase, R. Kimura, R. Masuda and K. Goto, New J. Chem., 2019, 43, 6830 DOI: 10.1039/C9NJ01072F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements