Issue 5, 2017

Matrix effects using an ICP-MS with a single positive ion lens and grounded stop: analyte mass dependent?

Abstract

Matrix effects in ICP-MS are generally considered to be more severe for heavy matrix elements and light analyte elements, consistent with space charge repulsion of ions during their travel from the plasma to the mass analyzer. However, the severity of matrix-induced changes in analyte sensitivity as a function of analyte mass may depend on the ion optics design, voltages applied to the ion optics and plasma parameters (robustness). Comprehensive characterization of matrix effects using an instrument with ion optics consisting of a grounded stop, a single positive cylindrical lens and a grounded aperture prior to the RF quadrupole is described. Matrix effects were studied as a function of analyte mass, matrix mass, matrix element concentration, lens voltage, and nebulizer gas flow rate. The effects of high concentrations of a wide mass range of matrix elements (Na, Cu, Y, In, Cs, Tb, Lu, and Tl) on analyte sensitivities with a wide range of masses (7Li+, 11B+, 24Mg+, 45Sc+, 60Ni+, 71Ga+, 75As+, 88Sr+, 111Cd+, 138Ba+, 153Eu+, 172Yb+, 209Bi+, and 238U+) were investigated. Matrix effects for equimolar matrix element concentrations were more severe as the matrix element mass increased. However, the severity of matrix effects depended less on the analyte ion mass than expected. Furthermore, matrix effects on high mass analyte sensitivities were more severe than those reported for first generation ICP-MS instruments.

Graphical abstract: Matrix effects using an ICP-MS with a single positive ion lens and grounded stop: analyte mass dependent?

Supplementary files

Article information

Article type
Paper
Submitted
28 jan 2017
Accepted
15 mar 2017
First published
17 mar 2017

J. Anal. At. Spectrom., 2017,32, 951-966

Matrix effects using an ICP-MS with a single positive ion lens and grounded stop: analyte mass dependent?

J. W. Olesik and S. Jiao, J. Anal. At. Spectrom., 2017, 32, 951 DOI: 10.1039/C7JA00043J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements