Issue 15, 2024

Modelling the innate immune system in microphysiological systems

Abstract

This critical review aims to highlight how modeling of the immune response has adapted over time to utilize microphysiological systems. Topics covered here will discuss the integral components of the immune system in various human body systems, and how these interactions are modeled using these systems. Through the use of microphysiological systems, we have not only expanded on foundations of basic immune cell information, but have also gleaned insight on how immune cells work both independently and collaboratively within an entire human body system.

Graphical abstract: Modelling the innate immune system in microphysiological systems

Article information

Article type
Critical Review
Submitted
25 sep 2023
Accepted
09 maj 2024
First published
03 jul 2024
This article is Open Access
Creative Commons BY license

Lab Chip, 2024,24, 3604-3625

Modelling the innate immune system in microphysiological systems

M. J. Rupar, H. Hanson, S. Rogers, B. Botlick, S. Trimmer and J. J. Hickman, Lab Chip, 2024, 24, 3604 DOI: 10.1039/D3LC00812F

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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