Issue 41, 2023

Green multicomponent synthesis of pyrano[2,3-c]pyrazole derivatives: current insights and future directions

Abstract

The past decade has witnessed significant progress in synthesizing structurally diverse and biologically relevant pyrano[2,3-c]pyrazole derivatives through the integration of green methodologies. This review summarizes the recent advances in the green multicomponent synthesis of pyrano[2,3-c]pyrazole and spiro-pyrano[2,3-c]pyrazole derivatives. These include the application of energy-efficient techniques such as microwave and ultrasound-assisted synthesis, benign catalysts and biodegradable composites, solvent selection with a focus on water as a renewable and non-toxic medium, and solvent-free conditions. The review consolidates the current knowledge and future research directions, providing a valuable resource for researchers dedicated to advancing green chemistry practices.

Graphical abstract: Green multicomponent synthesis of pyrano[2,3-c]pyrazole derivatives: current insights and future directions

Article information

Article type
Review Article
Submitted
16 aug 2023
Accepted
22 sep 2023
First published
02 okt 2023
This article is Open Access
Creative Commons BY license

RSC Adv., 2023,13, 28798-28833

Green multicomponent synthesis of pyrano[2,3-c]pyrazole derivatives: current insights and future directions

A. Ahmad, S. Rao and N. S. Shetty, RSC Adv., 2023, 13, 28798 DOI: 10.1039/D3RA05570A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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