Issue 4, 2023

pH-Responsive wound dressings: advances and prospects

Abstract

Wound healing is a complex and dynamic process, in which the pH value plays an important role in reflecting the wound status. Wound dressings are materials that are able to accelerate the healing process. Among the multifunctional advanced wound dressings developed in recent years, pH-responsive wound dressings, especially hydrogels, show great potential owing to their unique properties of adjusting their functions according to the wound conditions, thereby allowing the wound to heal in a regulated manner. However, a comprehensive review of pH-responsive wound dressings is lacking. This review summarizes the design strategies and advanced functions of pH-responsive hydrogel wound dressings, including their excellent antibacterial properties and significant pro-healing abilities. Other advanced pH-responsive materials, such as nanofibers, composite films, nanoparticle clusters, and microneedles, are also classified and discussed. Next, the pH-monitoring functions of pH-responsive wound dressings and the related pH indicators are summarized in detail. Finally, the achievements, challenges, and future development trends of pH-responsive wound dressings are discussed.

Graphical abstract: pH-Responsive wound dressings: advances and prospects

Article information

Article type
Review Article
Submitted
11 dec 2022
Accepted
31 jan 2023
First published
28 feb 2023

Nanoscale Horiz., 2023,8, 422-440

pH-Responsive wound dressings: advances and prospects

Z. Han, M. Yuan, L. Liu, K. Zhang, B. Zhao, B. He, Y. Liang and F. Li, Nanoscale Horiz., 2023, 8, 422 DOI: 10.1039/D2NH00574C

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