Issue 40, 2021

A multifunctional divergent scaffold to access the formal syntheses of various sesquiterpenoids

Abstract

The development of a divergent scaffold able to access an array of diverse natural sesquiterpenoids is described. The route unifies the scope of previously reported plans of our group to allow the scalable synthesis of 8,12-furo and lactone sesquiterpenoid carbocyclic cores of elemanes, germacranes, guaianes, cadinanes, lindenanes and myliols. The formal syntheses of furogermenone, methyl-curdionolide, zedoarol, qweicurculactone, lindenene and sarcandralactone A are reported.

Graphical abstract: A multifunctional divergent scaffold to access the formal syntheses of various sesquiterpenoids

Supplementary files

Article information

Article type
Communication
Submitted
01 sep 2021
Accepted
17 sep 2021
First published
20 sep 2021
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2021,19, 8687-8690

A multifunctional divergent scaffold to access the formal syntheses of various sesquiterpenoids

V. P. Demertzidou, M. Kourgiantaki and A. L. Zografos, Org. Biomol. Chem., 2021, 19, 8687 DOI: 10.1039/D1OB01716K

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