Issue 3, 2017

Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing

Abstract

The concept of distributed manufacturing of chemicals is presented and discussed, with specific focus on the context of preparing molecules that can combat the development of geographically-localised resistant strains of infectious pathogens. Specifically we present the case of antimalarial compounds and demonstrate that the flow chemistry community have already designed both a machine capable of distrubuted chemical manufacturing and a module that would be capable of producing artemisin derivatives at the point of use.

Graphical abstract: Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing

Article information

Article type
Minireview
Submitted
06 mar 2017
Accepted
29 mar 2017
First published
03 apr 2017

React. Chem. Eng., 2017,2, 281-287

Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing

J. L. Howard, C. Schotten and D. L. Browne, React. Chem. Eng., 2017, 2, 281 DOI: 10.1039/C7RE00034K

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