Issue 8, 2014

Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

Abstract

Electrostatic interaction-mediated enzymatic-hydrolysis of poly(lactide)-containing nanoscale assemblies is described. At physiological pH, degradable core–shell morphologies with charged shells can readily attract or repel enzymes carrying opposite or similar charges, respectively.

Graphical abstract: Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

Supplementary files

Article information

Article type
Communication
Submitted
06 aug 2013
Accepted
25 nov 2013
First published
04 dec 2013

Chem. Commun., 2014,50, 968-970

Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

S. Samarajeewa, R. P. Zentay, N. D. Jhurry, A. Li, K. Seetho, J. Zou and K. L. Wooley, Chem. Commun., 2014, 50, 968 DOI: 10.1039/C3CC46013D

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