Issue 31, 2011

Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray

Abstract

The binding of seven multivalent glycoconjugates displaying linear or antenna-like structures and different electronic environments were evaluated towards PA-IL on a DNA-based carbohydrate microarray. The affinity can be modulated by the charge and the topology of the galactosylated derivatives.

Graphical abstract: Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray

Supplementary files

Article information

Article type
Communication
Submitted
26 apr 2011
Accepted
20 jun 2011
First published
11 jul 2011

Chem. Commun., 2011,47, 8826-8828

Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray

Y. Chevolot, J. Zhang, A. Meyer, A. Goudot, S. Rouanet, S. Vidal, G. Pourceau, J. Cloarec, J. Praly, E. Souteyrand, J. Vasseur and F. Morvan, Chem. Commun., 2011, 47, 8826 DOI: 10.1039/C1CC12428E

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