Issue 4, 2021

Coherent anti-Stokes Raman scattering imaging of microcalcifications associated with breast cancer

Abstract

Chemical imaging of calcifications was demonstrated in the depth of a tissue. Using long wavelength excitation, broadband coherent anti-Stokes Raman scattering and hierarchical cluster analysis, imaging and chemical analysis were performed 2 mm below the skin level in a model system. Applications to breast cancer diagnostics and imaging are discussed together with the methods to further extend the depth and improve the spatial resolution of chemical imaging.

Graphical abstract: Coherent anti-Stokes Raman scattering imaging of microcalcifications associated with breast cancer

Article information

Article type
Paper
Submitted
01 okt 2020
Accepted
23 nov 2020
First published
09 dec 2020

Analyst, 2021,146, 1253-1259

Author version available

Coherent anti-Stokes Raman scattering imaging of microcalcifications associated with breast cancer

G. I. Petrov, R. Arora and V. V. Yakovlev, Analyst, 2021, 146, 1253 DOI: 10.1039/D0AN01962C

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