Assigning the Absolute Configuration of Inositol Poly- and Pyrophosphates by NMR Using a Single Chiral Solvating Agent

Kevin Ritter, Nikolaus Jork, Anne-Sophie Unmüßig, Maja Köhn and Henning J. Jessen

Biomolecules, 2023, 13, 1150
DOI: 10.3390/biom13071150

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

Pierre Raia, Kitaik Lee, Simon M. Bartsch, Felix Rico-Resendiz, Daniela Portugal-Calisto, Oscar Vadas, Vikram Govind Panse, Dorothea Fiedler and Michael Hothorn

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-56937-0

Fluorination Influences the Bioisostery of Myo‐Inositol Pyrophosphate Analogs

Sarah Hostachy, Huanchen Wang, Guangning Zong, Katy Franke, Andrew M. Riley, Peter Schmieder, Barry V. L. Potter, Stephen B. Shears and Dorothea Fiedler

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202302426

Beyond Triphosphates: Reagents and Methods for Chemical Oligophosphorylation

Scott M. Shepard, Henning J. Jessen and Christopher C. Cummins

J. Am. Chem. Soc., 2022, 144, 7517
DOI: 10.1021/jacs.1c07990

Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia–reperfusion injury by elevating plasma adiponectin

Lin Fu, Jimin Du, David Furkert, Megan L Shipton, Xiaoqi Liu, Tim Aguirre, Alfred C Chin, Andrew M Riley, Barry V L Potter, Dorothea Fiedler, Xu Zhang, Yi Zhu and Chenglai Fu

Cardiovascular Research, 2024, 120, 954
DOI: 10.1093/cvr/cvae017

Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe

Natascha Andrea Kuenzel, Abel R. Alcázar-Román, Adolfo Saiardi, Simon M. Bartsch, Sarune Daunaraviciute, Dorothea Fiedler and Ursula Fleig

JoF, 2022, 8, 933
DOI: 10.3390/jof8090933

Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I

Xiaoqi Liu, Zixuan Zhang, Tim Aguirre, Megan L. Shipton, Lin Fu, Jimin Du, David Furkert, Ji Qi, Alfred C. Chin, Andrew M. Riley, Tong Liu, Xu Zhang, Barry V.L. Potter, Dorothea Fiedler, Yi Zhu and Chenglai Fu

Metabolism, 2025, 163, 156098
DOI: 10.1016/j.metabol.2024.156098

Versatile signaling mechanisms of inositol pyrophosphates

Minh Nguyen Trung, David Furkert and Dorothea Fiedler

Current Opinion in Chemical Biology, 2022, 70, 102177
DOI: 10.1016/j.cbpa.2022.102177

Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsP5 and InsP8 in mammalian cells

Ji Qi, Linhui Shi, Limei Zhu, Yuanyuan Chen, Hong Zhu, Weiwei Cheng, Alex F. Chen and Chenglai Fu

J. of Cardiovasc. Trans. Res., 2024, 17, 197
DOI: 10.1007/s12265-023-10427-0