Aminated probe addition to fungal crude extract allows building molecular networks where captured compounds of different families are gathered together.
Azaphilones 8 and 9 isolated from a deep-sea derived Penicillium sp. SCSl041030 dramatically promoted axonal regrowth against Aβ25–35 induced axonal atrophy, which is the first report of azaphilones with neuroprotective effects.
The intricate street music box with a series of pins or teeth on a rotating cylinder or disc to play beautiful musical tunes. As exemplified by fungi-derived natural products with structural complexities and diverse bioactivities produced through different biosynthetic pathways.
First report of the chemical diversity study of deep-sea cold-seep-derived fungi triggered by the histone deacetylase inhibitor SAHA.
A comprehensive review of 1256 new MNPs including a novel cytotoxic alkaloid PM742 from the sponge Discodermia sp.