This feature article provides a comprehensive review of the major advances in the field of the transition-metal-free C–S bond cleavage of organosulfur compounds.
In this review, we present a comprehensive overview of our recent advancements in the methodology of electrochemically assisted radical generation and its subsequent application in the synthesis and functionalization of diverse N/S-heterocyclic compounds.
A simple and efficient approach was developed via the 1,3-dianionic annulation of acetone to afford multifunctional phenols.
We developed a benign, enzyme-catalyzed bromination of α-oxo ketene dithioacetals using CiVCPO in an aqueous micellar media assisted by the TPGS-750-M surfactant, overcoming solubility challenges and achieving high yields (up to 99%; 23 examples).
One-pot multicomponent reactions were developed for the synthesis of tetrasubstituted aminothiophenes in water. The column chromatography-free approach was found to be useful for the synthesis of pharmaceutically active analogues.