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Multitargeting the Action of 5-HT6 Serotonin Receptor Ligands by Additional Modulation of Kinases in the Search for a New Therapy for Alzheimer’s Disease: Can It Work from a Molecular Point of View?

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Front. Pharmacol., 2023, 14
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MARK4 promotes the malignant phenotype of gastric cancer through the MAPK/ERK signaling pathway

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Topological influence of immediate-early genes in brain genetic networks and their link to Alzheimer's disease

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Recent Advances in the Development and Characterization of Electrochemical and Electrical Biosensors for Small Molecule Neurotransmitters

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Tauopathy in AD: Therapeutic Potential of MARK-4

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In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia

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Inhibition of microtubule affinity regulating kinase 4 by an acetylcholinesterase inhibitor, Huperzine A: Computational and experimental approaches

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Unraveling human transferrin-tryptamine interactions: a computational and biophysical approach to Alzheimer’s disease therapeutics

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Front. Pharmacol., 2025, 16
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Inhibition of Microtubule Affinity Regulating Kinase 4 by Metformin: Exploring the Neuroprotective Potential of Antidiabetic Drug through Spectroscopic and Computational Approaches

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Nanozyme-triggered polymerization amplification strategy for constructing highly sensitive surface plasmon resonance immunosensing

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Systemic Modulators: Potential Mechanism for the 5-HT System to Mediate Exercise Amelioration in Alzheimer's Disease

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Apigenin-mediated MARK4 inhibition: a novel approach in advancing Alzheimer’s disease therapeutics

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Desmodin and isopongachromene as potential inhibitors of cyclin-dependent kinase 5: phytoconstituents targeting anticancer and neurological therapy

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Investigation of Charged Small Molecule–Aptamer Interactions with Surface Plasmon Resonance

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Experimental and theoretical studies on structural changes in the microtubule affinity-regulating kinase 4 (MARK4) protein induced by N-hetarenes: a new class of therapeutic candidates for Alzheimer’s disease

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Synthesis of 3‐hydroxy‐2‐naphthohydrazide‐based hydrazones and their implications in diabetic management via in vitro and in silico approaches

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Linagliptin and Empagliflozin Inhibit Microtubule Affinity Regulatory Kinase 4: Repurposing Anti-Diabetic Drugs in Neurodegenerative Disorders Using In Silico and In Vitro Approaches

Akhtar Atiya, Debarati Das Gupta, Abdulrhman Alsayari, Mohammed Alrouji, Abdulmajeed Alotaibi, Sharaf E. Sharaf, Waleed Al Abdulmonem, Nasser M. Alorfi, K. M. Abdullah and Anas Shamsi

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Comparative metabolic profiling of mycelia, fermentation broth, spore powder and fruiting bodies of Ophiocordyceps gracilis by LC–MS/MS

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Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases

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