Recent breakthroughs in ring-opening annulation reactions of aziridines

Deepak Ranjan Mishra and Nilima Priyadarsini Mishra

Org. Biomol. Chem., 2025, 23, 2967
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Construction of 4-spiroannulated tetrahydroisoquinoline skeletonsviaa sequential ring opening of aziridines and Pictet–Spengler reaction

Siyang Xing, Chenyu Wang, Tingxuan Gao, Yuhan Wang, Hongzheng Wang, Hanfei Wang, Kui Wang and Bolin Zhu

New J. Chem., 2022, 46, 2553
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Synthesis of chiral β-substituted γ-amino-butyric acid derivativesviaenantioconvergent ring opening of racemic 2-(hetero)aryl aziridines with ketene silyl acetals

Ling Qi, Pei-Jun Yang, Wen-Tao Ji, Gui-De Tao, Gaosheng Yang and Zhuo Chai

Org. Chem. Front., 2022, 9, 4699
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Enantioselective intramolecular Pictet–Spengler type annulation of indole-linked 3-methyleneisoindolin-1-ones

Min Liu, Wenzhe Li, Min Huang, Yingkun Yan, Min Li, Lianyi Cao and Xiaomei Zhang

New J. Chem., 2022, 46, 9582
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Palladium-catalyzed cascade cyclization/intramolecular redox-relay Heck arylation of alkenols: access to tetrahydro-β-carbolines from 2-(hydroxyalkenynyl)sulfonanilides

Tao Liu, Tuanli Yao, Ruihua Guo and Xiangyang Qin

Org. Chem. Front., 2023, 10, 3504
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Application of 3-Alkyl-2-vinylindoles in Catalytic Asymmetric Dearomative (2+3) Cycloadditions

Ke-Wei Chen, Dan-Dan Wang, Si-Jia Liu, Xue Wang, Yu-Chen Zhang, Yi-Ming Tian, Qiong Wu and Feng Shi

J. Org. Chem., 2021, 86, 10427
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Synthesis of Pyridazino[4,5‐b]indoles by [3+3] Annulation of 2‐Alkenylindoles and Hydrazonyl Chlorides

Shuting Zhang, Xinyu Zhang, Lesong Li, Zhenyu Shi and Yang Wang

Chemistry A European J, 2024, 30
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Catalytic Aminium Radical-Cation Salt (Magic Blue)-Initiated SN2-Type Nucleophilic Ring-Opening Transformations of Aziridines

Bharat Singh, Suraj Kashyap, Shishir Singh, Sikha Gupta and Manas K. Ghorai

J. Org. Chem., 2024, 89, 2247
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Construction of Bridged Aza- and Oxa-[n.2.1] Skeletons via an Intramolecular Formal [3+2] Cycloaddition of Aziridines and Epoxides with Electron-Deficient Alkenes

Siyang Xing, Yuhan Wang, Changkun Jin, Shaochen Shi, Yihui Zhang, Ziya Liao, Kui Wang and Bolin Zhu

J. Org. Chem., 2022, 87, 6426
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NIS-promoted intramolecular cyclization of allenamides for the synthesis of tetrahydro-β-carbolines

Na Ding, Xue-Fang Zhong, Xiao-Ju Tan, Lan Yang, Tong Hong, Xiao-Xiao Li and Zhi-Gang Zhao

Tetrahedron Letters, 2021, 81, 153334
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Recent Advances on the Synthesis and Application of Tetrahydro‐β‐Carbolines

Youlong Du, Anas Semghouli, Haibo Mei, Loránd Kiss and Jianlin Han

Adv Synth Catal, 2024, 366, 3050
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One-Pot Total Synthesis of Natural Products Nitramarine, Nitraridine, and Analogues via a Cascade Oxidation/Pictet–Spengler Condensation/Annulation Process

Ying-Chun Song, Wen-Hui Cao, Ming-Xuan Wang, Run-Qing Wang, Yuan-Yuan Sun, An-Xin Wu and Yan-Ping Zhu

J. Org. Chem., 2024, 89, 12832
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Ruthenium(II)-Catalyzed Remote C–H Alkylation of Arenes Using Diverse N-Directing Groups through Aziridine Ring Opening

Hongyan Lan, Yingzhen Liu, Lutz Ackermann, Lanfen Wang and Dingyi Wang

Org. Lett., 2024, 26, 7993
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Diastereoselective Access to cis‐1,4‐Disubstitued Tetrahydro‐γ‐carbolines via a [Cp*RhCl2]2‐Catalyzed Formal [3+3]‐Cycloaddition

Siyang Xing, Tingxuan Gao, Changkun Jin, Hongguo Dong, Xueying Shao, Kui Wang and Bolin Zhu

Adv Synth Catal, 2023, 365, 104
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Rapid Synthesis of 3-Methyleneisoindolin-1-ones via Metal-Free Tandem Reactions of Ester-Functionalized Aziridines

Siyang Xing, Changkun Jin, Panpan Zhang, Jingmeng Yang, Yuxia Liang, Xinglian Ao, Wenyi Pi, Kui Wang and Bolin Zhu

J. Org. Chem., 2024, 89, 5153
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Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

Xiaochen Tian, Tengfei Xuan, Jingkun Gao, Xinyu Zhang, Tao Liu, Fengbiao Luo, Ruochen Pang, Pengcheng Shao, Yun-Fang Yang and Yang Wang

Nat Commun, 2024, 15
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Lewis Acid-Catalyzed [2+4] Cyclization of 3-Alkyl-2-vinylindoles with α,β-Unsaturated N-Sulfonyl Ketimines

Lixing Sun, Tingting Sun, Haiqing Wang, Shufang Wu, Xiaoye Wang, Tianya Liu and Yuchen Zhang

Chinese Journal of Organic Chemistry, 2023, 43, 2178
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Construction of isoindolin-1-ones via tandem reaction of ester-functionalized aziridines with amines

Fangfang Jing, Zhengyu Liu, Lvrong Jin, Yuhao Pang, Bo Pang, Siyang Xing and Bolin Zhu

Synthetic Communications, 2025, 55, 76
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Lewis acid-catalyzed [4 + 2] cycloaddition of 3-alkyl-2-vinylindoles with β,γ-unsaturated α-ketoesters

Yuwen Sun, Zhaoshan Wang, Shufang Wu, Yuchen Zhang and Feng Shi

Green Synthesis and Catalysis, 2022, 3, 84
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