Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1

Jing Zhang, Qiu-Sha Pan, Xing-Kai Qian, Xiang-Lu Zhou, Ya-Jie Wang, Rong-Jing He, Le-Tian Wang, Yan-Ran Li, Hong Huo, Cheng-Gong Sun, Lei Sun, Li-Wei Zou and Ling Yang

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022, 37, 629
DOI: 10.1080/14756366.2022.2029855

Screening of natural inhibitors against peptidyl arginine deiminase 4 from herbal extracts by a high-performance liquid chromatography ultraviolet-visible based method

Juanjuan Zhao, Yanfeng Li, Chunli Gao, Zeyuan Zhao, Shengxiang Zhang, Jianhui Dong, Haiyue Zuo, Xufei Chen, Binxi Xie, Zhengwei Guo, Yanming Wang, Hui Li and Yangyang Bian

Journal of Chromatography A, 2024, 1716, 464643
DOI: 10.1016/j.chroma.2024.464643

Screening of peptidyl arginine deiminase 4 inhibitors in traditional herbal medicines

Yanfeng Li, Chunli Gao, Juanjuan Zhao, Zeyuan Zhao, Binxi Xie, Haiyue Zuo, Shengxiang Zhang, Jianhui Dong, Xufei Chen, Hui Li and Yangyang Bian

Fitoterapia, 2024, 177, 106095
DOI: 10.1016/j.fitote.2024.106095

High-throughput optical assays for sensing serine hydrolases in living systems and their applications

Qiang Jin, Li-Lin Song, Le-Le Ding, Jing Zhang, Dan-Dan Wang, Yun-Qing Song, Li-Wei Zou and Guang-Bo Ge

TrAC Trends in Analytical Chemistry, 2022, 152, 116620
DOI: 10.1016/j.trac.2022.116620

Storax Inhibits Caveolae-Mediated Transcytosis at Blood-Brain Barrier After Ischemic Stroke in Rats

Min Zhou, Dongna Li, Qian Shen, Lei Gao, Pengwei Zhuang, Yanjun Zhang and Hong Guo

Front. Pharmacol., 2022, 13
DOI: 10.3389/fphar.2022.876235

Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay

Li-Juan Ma, Xu-Dong Hou, Xiao-Ya Qin, Rong-Jing He, Hao-Nan Yu, Qing Hu, Xiao-Qing Guan, Shou-Ning Jia, Jie Hou, Tao Lei and Guang-Bo Ge

Journal of Pharmaceutical Analysis, 2022, 12, 683
DOI: 10.1016/j.jpha.2022.04.002

Discovery and characterization of flavonoids in vine tea as catechol-O-methyltransferase inhibitors

Dong-Fang Zhao, Yu-Fan Fan, Hao-Nan Yu, Fan-bin Hou, Yan-Wei Xiang, Ping Wang, Guang-Bo Ge, Ling Yang and Jian-Guang Xu

Fitoterapia, 2021, 152, 104913
DOI: 10.1016/j.fitote.2021.104913

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans

Feng Zhang, Hong-Xin Li, Tian-Tian Zhang, Yuan Xiong, Hao-Nan Wang, Zhen-Hui Lu, Lei Xiong, Yu-Qi He and Guang-Bo Ge

Chemico-Biological Interactions, 2022, 351, 109744
DOI: 10.1016/j.cbi.2021.109744

Storax, A Promising Botanical Medicine for Treating Cardio-Cerebrovascular Diseases: A Review

Zhuo Xu, Danni Lu, Jianmei Yuan, Mihong Ren, Rong Ma, Qian Xie, Yong Li, Jinxiu Li and Jian Wang

Front. Pharmacol., 2021, 12
DOI: 10.3389/fphar.2021.785598