The fate of mamaku gum in the gut: effect on in vitro gastrointestinal function and colon fermentation by human faecal microbiota

Akshay Bisht, Kelvin K. T. Goh and Lara Matia-Merino

Food Funct., 2023, 14, 7024
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In vitro simulated digestion and fermentation of Lithocarpus litseifolius [Hance] Chun green tea polysaccharides and their modulation of the gut microbiota

Qingying Luo, Xuewei Liao, Lijia Zhang, Zhengfeng Fang, Hong Chen, Bin Hu, Yuntao Liu and Zhen Zeng

Food Funct., 2026, 17, 150
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In vitro simulated digestion and fermentation behaviors of polysaccharides from Pleurotus cornucopiae and their impact on the gut microbiota

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Food Funct., 2024, 15, 10051
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Structural characteristics and in vitro fermentation patterns of polysaccharides from Boletus mushrooms

Li Chen, Yuxin Wang, Jiaxin Liu, Zhiyuan Hong, Ka-Hing Wong, Jia-Chi Chiou, Baojun Xu, Carlos L. Cespedes-Acuña, Weibin Bai and Lingmin Tian

Food Funct., 2023, 14, 7912
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Effect of polysaccharides from Tibetan turnip (Brassica rapaL.) on the gut microbiome afterin vitrofermentation andin vivometabolism

Lin Liu, Chang Liu, Hanyi Hua, Wenjin Zhao, Hongkang Zhu, Yuliang Cheng, Yahui Guo and He Qian

Food Funct., 2022, 13, 3063
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Advances in the in vitro digestion and fermentation of polysaccharides

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Characteristics and properties of a polysaccharide isolated from Wolfiporia cocos as potential dietary supplement for IBS

Xuan Yang, Shun Lu, Yuhan Feng, Chongjiang Cao, Yanliang Zhang and Shujie Cheng

Front. Nutr., 2023, 10
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The influence of in vitro gastrointestinal digestion and fecal fermentation on the flowers of Juglans regia: Changes in the active compounds and bioactivities

Ximeng Jin, Yuerong Ru, Xuechun Zhang, Huan Kan, Ping Xiang, Xuemei He, Jian Sun, Xiahong He and Zhengxing Wang

Front. Nutr., 2022, 9
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Rich d-Fructose-Containing Polysaccharide Isolated from Myxopyrum smilacifolium Roots toward a Superior Antioxidant Biomaterial

Trung Hieu Le, Lam Son Le, Dang Giang Chau Nguyen, Thi Van Thi Tran, Xuan Anh Vu Ho, Thanh Minh Tran, Minh Nhung Nguyen, Viet Thang Nguyen, Thuy Trang Le, Thi Hong Chuong Nguyen, Chinh Chien Nguyen and Quyet Van Le

ACS Omega, 2022, 7, 47923
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The bioavailability of soybean polysaccharides and their metabolites on gut microbiota in the simulator of the human intestinal microbial ecosystem (SHIME)

Pin Chen, Xiaoqian Chen, Linlin Hao, Peng Du, Chun Li, Hongyang Han, Hanxue Xu and Libo Liu

Food Chemistry, 2021, 362, 130233
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Interactions between polysaccharides and gut microbiota: A metabolomic and microbial review

Dandan Zhang, Juan Liu, Hao Cheng, Hongliang Wang, Yuzhu Tan, Wuwen Feng and Cheng Peng

Food Research International, 2022, 160, 111653
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In vitro saliva-gastrointestinal digestion and fecal fermentation of Oudemansiella radicata polysaccharides reveal its digestion profile and effect on the modulation of the gut microbiota

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In vitro fermentation characteristics of polysaccharides from coix seed and its effects on the gut microbiota

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International Journal of Biological Macromolecules, 2024, 262, 129994
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Gut microbial fermentation promotes the intestinal anti-inflammatory activity of Chinese yam polysaccharides

Yajuan Bai, Yue Zhou, Ruifen Zhang, Yanxia Chen, Fengzhong Wang and Mingwei Zhang

Food Chemistry, 2023, 402, 134003
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Molecular weight-engineered lentinan fractions as prebiotic modulators: Steering gut microbiota for precision obesity intervention

Xiang Yan, Yi Shen, Qi Tao, Pengrui Shi, Qiongdan Zhang, Ye Qi, Qimeng Zhou, Qun Lu and Hongshan Liang

Food Research International, 2026, 226, 118169
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Chlorella pyrenoidosa Polysaccharides as a Prebiotic to Modulate Gut Microbiota: Physicochemical Properties and Fermentation Characteristics In Vitro

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Foods, 2022, 11, 725
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Bioactive composition and modulatory effects of Hed-Tean-Rad Mushroom, Macrocybe crassa on gut microbiota

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3 Biotech, 2022, 12
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Purification and Identification of a Multidomain Pectin from Phyllanthus emblica L.: Structure–Activity Relationship Analysis on Glycolipid-Lowering Activity via Gut Action Targets

Xiaoyu Duan, Mouming Zhao and Lianzhu Lin

J. Agric. Food Chem., 2026, 74, 3118
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Interaction of sulfated polysaccharides with intestinal Bacteroidales plays an important role in its biological activities

Xiaona Sun, Yili Liu, Pingrui Jiang, Shuang Song and Chunqing Ai

International Journal of Biological Macromolecules, 2021, 168, 496
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Digestive characteristics of Gastrodia elata Blume polysaccharide and related impacts on human gut microbiota in vitro

Qingxia Gan, Linlin Chen, Jiacheng Xian, Guangqin An, Haobo Wei and Yuntong Ma

Journal of Ethnopharmacology, 2024, 328, 118064
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In vitro fermentation characteristics and modulation effects of polysaccharide fractions from Schisandra sphenanthera on intestinal microflora

Chen Zhang, Lei Hao, Yadong Zhu, Xiaojia Zhang, Hongfei Zhao and Bolin Zhang

International Journal of Biological Macromolecules, 2025, 289, 138771
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Effect of in vitro simulated gastrointestinal digestion on the antioxidant activity, molecular weight, and microstructure of polysaccharides from Chinese yam

Xiaojuan Feng, Nana Bie, Jingyao Li, Mengli Zhang, Yihua Feng, Tingting Ding, Yue Zhao and Chunling Wang

International Journal of Biological Macromolecules, 2022, 207, 873
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In Vitro Gastrointestinal Digestion of Polyonatum cyrtonema Polysaccharides and Impact on Intestinal Flora

Ya Gao, Ying Xiao, Ling Yu, Qingjiu Tang, Lin Ye, Jinyan Wang, Yipeng Wang, Fangfang Zhang, Jianjin Zhou and Bhupendra M. Ghodki

Journal of Food Biochemistry, 2024, 2024, 1
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Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments

David C. Speksnijder, Nonke E. M. Hopman, Nina E. Kusters, Arjen Timmerman, Jantijn M. Swinkels, Pleun A. A. Penterman, Volker Krömker, Andrew J. Bradley, Nadine Botteldoorn, Ronette Gehring and Aldert L. Zomer

Sci Rep, 2022, 12
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Study on extraction optimization, structure features, and bioactivities of an Oudemansiella raphanipies polysaccharide

Dianhui Luo and Zhaojing Wang

Process Biochemistry, 2023, 126, 136
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Honey-processed Astragalus polysaccharides exhibit enhanced Qi-tonifying effects via structural modifications and microbiome-metabolome regulation

Zhaohui Lin, Lili Lu, Wenlong Guo, Shuyu Han, Yufei Tian, Hongyuan Chen and Wen Rui

Food Bioscience, 2025, 68, 106560
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Chain conformation, mucoadhesive properties of fucoidan in the gastrointestinal tract and its effects on the gut microbiota

Aijun Chen, Yatong Liu, Tao Zhang, Yu Xiao, Xiaoqi Xu, Zheng Xu and Hong Xu

Carbohydrate Polymers, 2023, 304, 120460
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Effect of various extraction methods on the physicochemical properties, antioxidant, and anti-inflammatory activities of mung bean (Vigna radiata L.) skin polysaccharides

Xiao Ding, Tingting Li, Jiajia Zhao, Wafaa Khalid, Mingcon Fan, Haifeng Qian, Yan Li and Li Wang

International Journal of Biological Macromolecules, 2025, 311, 143969
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In vitro gastrointestinal digestion of Lentinus squarrosulus powder and impact on human fecal microbiota

Francis Ayimbila, Supatcharee Siriwong, Massalin Nakphaichit and Suttipun Keawsompong

Sci Rep, 2022, 12
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The Effect of Opuntia ficus Mucilage Pectin and Citrus aurantium Extract Added to a Food Matrix on the Gut Microbiota of Lean Humans and Humans with Obesity

Nancy Abril Estrada-Sierra, Marisela Gonzalez-Avila, Judith-Esmeralda Urias-Silvas, Gabriel Rincon-Enriquez, Maria Dolores Garcia-Parra and Socorro Josefina Villanueva-Rodriguez

Foods, 2024, 13, 587
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Effect of digestive properties and gut microbiota structure of steam-exploded Laminaria japonica polysaccharide: in vitro dynamic human gastrointestinal systems

Yaqing Lin, Jiabin Wu, Bin Xiong, Lin Wang, Zhikun Zeng, Baodong Zheng, Yi Zhang and Lei Pan

LWT, 2025, 225, 117866
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Controlled biosynthesis of curdlan oligosaccharides with tunable degree of polymerization and their prebiotic effects on gut microbiota

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Gastrointestinal digestion fate of Tremella fuciformis polysaccharide and its effect on intestinal flora: an in vitro digestion and fecal fermentation study

Xiangyang Zhu, Jing Su, Lan Zhang, Fan Si, Dapeng Li, Yang Jiang and Chen Zhang

FIA, 2024, 3, 202
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In Vitro Simulation of Human Colonic Fermentation: A Practical Approach towards Models’ Design and Analytical Tools

Elena Veintimilla-Gozalbo, Andrea Asensio-Grau, Joaquim Calvo-Lerma, Ana Heredia and Ana Andrés

Applied Sciences, 2021, 11, 8135
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Comparing the antioxidation and bioavailability of polysaccharides from extruded and unextruded Baijiu vinasses via in vitro digestion and fecal fermentation

Yizhou Liu, Xiong Li, Hui Qin, Mengyang Huang, Beidou Xi, Jian Mao and Suyi Zhang

International Journal of Biological Macromolecules, 2024, 276, 133681
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In vivo absorption, in vitro simulated digestion and fecal fermentation properties of polysaccharides from Pinelliae Rhizoma Praeparatum Cum Alumine and their effects on human gut microbiota

Kui-Xu Gao, Xi Peng, Jing-Ya Wang, Yao Wang, Ke Pei, Xiang-Long Meng, Shuo-Sheng Zhang, Mei-Bian Hu and Yu-Jie Liu

International Journal of Biological Macromolecules, 2024, 266, 131391
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Role, relevance, and possibilities of in vitro fermentation models in human dietary, and gut‐microbial studies

Vineet Singh, HyunWoo Son, GyuDae Lee, Sunwoo Lee, Tatsuya Unno and Jae‐Ho Shin

Biotech & Bioengineering, 2022, 119, 3044
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The Influence of Polysaccharides on Lipid Metabolism: Insights from Gut Microbiota

Qianqian Huang, Yanhui Zhang, Qiang Chu and Haizhao Song

Molecular Nutrition Food Res, 2024, 68
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Extraction, structure characterization, carboxymethylation and antioxidant activity of acidic polysaccharides from Craterellus cornucopioides

Yuntao Liu, Xiaoyu Duan, Mingyue Zhang, Cheng Li, Zhiqing Zhang, Bin Hu, Aiping Liu, Qin Li, Hong Chen, Zizhong Tang, Wenjuan Wu and Daiwen Chen

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Structurally Orientated Rheological and Gut Microbiota Fermentation Property of Mannans Polysaccharides and Oligosaccharides

Jing Wang, Sheng Ke, Padraig Strappe, Ming Ning and Zhongkai Zhou

Foods, 2023, 12, 4002
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Comprehensive analysis of Sparassis crispa polysaccharide characteristics during the in vitro digestion and fermentation model

Wenyi Zhang, Bin Hu, Chang Liu, Hanyi Hua, Yahui Guo, Yuliang Cheng, Weirong Yao and He Qian

Food Research International, 2022, 154, 111005
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In vitro digestion properties of Laiyang pear residue polysaccharides and it counteracts DSS-induced gut injury in mice via modulating gut inflammation, gut microbiota and intestinal barrier

Liqing Fan, Xiangyang Zhu, Dexi Zhang, Dapeng Li and Chen Zhang

International Journal of Biological Macromolecules, 2024, 267, 131482
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Physicochemical and in vitro digestive characteristics of water-soluble chickpea polysaccharides extracted using ultrasound and freeze-thaw methods

Hanluo Li, Yiming Wen, Mingyang Ni, Aijia Zheng, Peihao Gao, Seockmo Ku, Xiangwei Zhu and Sini Kang

Food Chemistry: X, 2025, 28, 102560
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Isolation of a novel polysaccharide from Tribonema minus and preparation of polysaccharide–selenium nanoparticles with enhanced antioxidant activity

Rundong Yang, Yuhao Guo, Yanchao Mao, Wenxiang Zhang, Feifei Wang and Zhenzhou Zhu

Algal Research, 2025, 88, 104020
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Dietary compounds in modulation of gut microbiota-derived metabolites

Wuwen Feng, Juan Liu, Hao Cheng, Dandan Zhang, Yuzhu Tan and Cheng Peng

Front. Nutr., 2022, 9
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Mathematical models of the colonic microbiota: an evaluation of accuracy using in vitro fecal fermentation data

Vitor Geniselli da Silva, Nick William Smith, Jane Adair Mullaney, Nicole Clémence Roy, Clare Wall and Warren Charles McNabb

Front. Nutr., 2025, 12
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In vitro digestion and fecal fermentation behaviors of polysaccharides from Ziziphus Jujuba cv. Pozao and its interaction with human gut microbiota

Xue Han, Qian Zhou, Zhe Gao, Xuan Lin, Kaixuan Zhou, Xinlong Cheng, Bimal Chitrakar, Hong Chen and Wen Zhao

Food Research International, 2022, 162, 112022
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In Vitro Fecal Fermentation of Euphorbia humifusa-Derived Polysaccharides and Their Protective Effect against Ulcerative Colitis in Mice

Ning Xiang, Jianbo Zhao, Siqiao Chang, Shasha Li, Shuwen Liu and Chan Wang

Foods, 2023, 12, 751
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Chemical structure of a novel heteroglycan polysaccharide isolated from the biomass of Ophiocordyceps Sobolifera

Thi Van Thi Tran, Van Khoa Tran, Xuan Anh Vu Ho, Lam Son Le, Trung Hieu Le, Thi Hong Chuong Nguyen, Chinh Chien Nguyen, Soo Young Kim and Quyet Van Le

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Digestive characteristics of Tibetan tea polyphenols and polysaccharides in vitro and their effects on gut microbiota

Zhen Zeng, Chunping Jiang, Fengshi Deng, Lijia Zhang, Qiyun Zhang, Zhengfeng Fang, Bin Hu, Hong Chen, Caixia Wang, Wenjuan Wu and Yuntao Liu

Food Chemistry, 2025, 483, 144289
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In vitro simulated digestion and fermentation characteristics of polysaccharide from oyster (Crassostrea gigas), and its effects on the gut microbiota

Yuyang Ma, Suisui Jiang and Mingyong Zeng

Food Research International, 2021, 149, 110646
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Valorization of Arabinoxylans from Wheat Bran via NaOH/Urea Extraction for Enhanced Prebiotic and Fermentation Properties

Chunping Chen, Min Luo, Cong Zheng, Luhuai Cui, Yonghui Dong, Caian He and Min Wang

ACS Sustainable Chem. Eng., 2025, 13, 12022
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Tea polysaccharides from Taiping Houkui may serve as a potential candidate for regulation of lipid metabolism: Roles of gut microbiota and metabolite in vitro

Yuexin Liu, Shicheng Lei, Ruyan Hou, Daxiang Li, Xiaochun Wan, Huimei Cai and Guijie Chen

Journal of Functional Foods, 2023, 102, 105469
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Comprehensive Review of Functional and Nutraceutical Properties of Craterellus cornucopioides (L.) Pers.

Mariana-Gabriela Bumbu, Mihaela Niculae, Irina Ielciu, Daniela Hanganu, Ilioara Oniga, Daniela Benedec, Mihaela-Ancuța Nechita, Vlad-Ionuț Nechita and Ioan Marcus

Nutrients, 2024, 16, 831
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Oudemansiella raphanipies Polysaccharides Improve Lipid Metabolism Disorders in Murine High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease

Haitao Jiang, Hua Zhu, Guangming Huo, Shengjie Li, Yulong Wu, Feng Zhou, Chun Hua and Qiuhui Hu

Nutrients, 2022, 14, 4092
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In vitro simulated digestion of different heat treatments sweet potato polysaccharides and effects on human intestinal flora

Chuan Liu, Yu Miao, Jingwen Zhao, Sijia Yang, Shihui Cheng, Wenjia Zhou, Wenkui Guo and Aili Li

Food Chemistry, 2025, 463, 141190
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Antioxidant properties and digestion behaviors of polysaccharides from Chinese yam fermented by Saccharomyces boulardii

Yiwen Shao, Qiaozhen Kang, Jiaqing Zhu, Changcheng Zhao, Limin Hao, Jinyong Huang, Jike Lu, Shiru Jia and Juanjuan Yi

LWT, 2022, 154, 112752
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In Vitro Digestion and Fecal Fermentation of Polysaccharides from Hawthorn and Its Impacts on Human Gut Microbiota

Kaixuan Zhou, Qian Zhou, Xue Han, Zhe Gao, Ruyan Peng, Xuan Lin, Xinlong Cheng and Wen Zhao

Processes, 2022, 10, 1922
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Structural analysis and in vitro fermentation characteristics of an Avicennia marina fruit RG-I pectin as a potential prebiotic

Jinwen Huang, Huiqi Wang, Huaqun Chen, Zidong Liu, Xuedong Zhang, Hao Tang, Shiying Wei, Wangting Zhou, Xinzhou Yang, Yonghong Liu, Longyan Zhao and Qingxia Yuan

Carbohydrate Polymers, 2024, 338, 122236
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Comprehensive evaluation of Flammulina velutipes residues polysaccharide based on in vitro digestion and human fecal fermentation

Yao Zhang, Liping Wang, Zihan Qiu, Yiting Yang, Tiezhu Wang, Muhammad Inam, Hongxia Ma, Haipeng Zhang, Chengguang He and Lili Guan

International Journal of Biological Macromolecules, 2024, 281, 136487
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In vitro digestion and fermentation by human fecal microbiota of polysaccharides from Clitocybe squamulose

Dongdong Guo, Jiayu Lei, Chang He, Zhijie Peng, Rongzhu Liu, Xu Pan, Junlong Meng, Cuiping Feng, Lijing Xu, Yanfen Cheng, Mingchang Chang and Xueran Geng

International Journal of Biological Macromolecules, 2022, 208, 343
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Black Trumpet [Craterellus cornucopioides (L.) Pers.]—Bioactive Properties and Prospects for Application in Medicine and Production of Health-Promoting Food

Iwona Adamska and Katarzyna Felisiak

Nutrients, 2024, 16, 1325
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In vivo absorption and fecal excretion of polysaccharides from the fruits of Lycium barbarum L. in rats through fluorescence labeling

Wangting Zhou, Xuhui Kan, Wei Dong, Yamei Yan, Jia Mi, Lu Lu, Youlong Cao, Yi Sun, Xiaoxiong Zeng and Wei Wang

International Journal of Biological Macromolecules, 2024, 278, 134613
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Oral absorption mechanisms of polysaccharides and potential as carriers for the construction of nano-delivery systems: A review

Bing Yang, Yan Xu, Weiye Zhang, Dandan Zhu, Bin Huang, Yanjun Yang, Xiaobin Jia and Liang Feng

International Journal of Biological Macromolecules, 2025, 310, 143184
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Zanthoxylum alkylamides improves hepatic glucose metabolism by regulating gut microbiota in STZ-induced T2DM rats

Xiaowei Peng, Bing Yang, Xunyu Wei, Lu Wang and Jianquan Kan

Fitoterapia, 2025, 184, 106623
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Simulated digestion and in vitro fermentation of a polysaccharide from lotus (Nelumbo nucifera Gaertn.) root residue by the human gut microbiota

Xueting Guan, Yujing Feng, Yunyao Jiang, Yeye Hu, Ji Zhang, Zhengpeng Li, Chao Song, Fu Li, Jincai Hou, Ting Shen and Weicheng Hu

Food Research International, 2022, 155, 111074
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In vitro simulated digestion of and microbial characteristics in colonic fermentation of polysaccharides from four varieties of Tibetan tea

Yaowen Tan, Meiwen Li, Keyang Kong, Yushan Xie, Zhen Zeng, Zhengfeng Fang, Cheng Li, Bin Hu, Xinjie Hu, Caixia Wang, Saiyan Chen, Wenjuan Wu, Xiguo Lan and Yuntao Liu

Food Research International, 2023, 163, 112255
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Effects of in vitro simulated digestion and fecal fermentation on the structure and regulating the glucose and lipid activity of a polysaccharide from Mori Folium

Lingyu Zhang, Tongtong Zhu, Ying Wang, Boli Zhang, Han Zhang, Lifeng Han, Erwei Liu and Zhifei Fu

International Journal of Biological Macromolecules, 2024, 280, 135595
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Effect of in vitro simulated digestion and fecal fermentation on Boletus auripes polysaccharide characteristics and intestinal flora

Qingying Luo, Xuejiao Li, Hongyu Li, Keyang Kong, Cheng Li, Zhengfeng Fang, Bin Hu, Caixia Wang, Saiyan Chen, Wenjuan Wu, Xiaolin Li, Yuntao Liu and Zhen Zeng

International Journal of Biological Macromolecules, 2023, 249, 126461
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Ultrasonic modification on the physicochemical, in vitro simulated digestion and colonic fermentation properties of Golden Flower Tibetan Tea Polysaccharides

Chen Xia, Sijia Zhao, Manyou Yu, Junlin Deng, Zhuoya Xiang, Jian Chen, Ting Zhang, Xiaobo Tang, Yongqing Zhu, Yan Jin, Ruiqi Zeng, Jiayuan Zhao, Liugang Shi and Bin Wu

LWT, 2025, 230, 118256
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Effects of in vitro digestion and fecal fermentation on physico-chemical properties and metabolic behavior of polysaccharides from Clitocybe squamulosa

Xueran Geng, Dongdong Guo, Tergun Bau, Jiayu Lei, Lijing Xu, Yanfen Cheng, Cuiping Feng, Junlong Meng and Mingchang Chang

Food Chemistry: X, 2023, 18, 100644
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A review on the edible mushroom as a source of special flavor: Flavor categories, influencing factors, and challenges

Chunping Jiang, Xiaoyu Duan, Lin Lin, Wenjuan Wu, Xiaolin Li, Zhen Zeng, Qingying Luo and Yuntao Liu

Food Frontiers, 2023, 4, 1561
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Health benefits of edible mushroom polysaccharides and associated gut microbiota regulation

Gaoxing Ma, Hengjun Du, Qiuhui Hu, Wenjian Yang, Fei Pei and Hang Xiao

Critical Reviews in Food Science and Nutrition, 2022, 62, 6646
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