Qiong Hu, Mei-Zhu Bao, Yuan-Jie Meng, Xin-Xing Liu, Wen-Xuan Zou, Jia-Lin Song, Jiaohang Wei, Dan-Ting Shen, Xiang Liu, Xiaohui Cao and Shang-Shi Zhang

Org. Chem. Front., 2024, 11, 6223
DOI: 10.1039/D4QO01347F

Recent approaches for the synthesis of heterocycles from amidines via a metal catalyzed C–H functionalization reaction

Youpeng Zuo, Pengfei Zuo, Meijun Liu, Xiaoqing Wang, Jun Du, Xiaoling Li, Pinghua Zhang and Zhenhua Xu

Org. Biomol. Chem., 2024, 22, 5014
DOI: 10.1039/D4OB00420E

C–F bond functionalizations via fluorinated carbenes

Yingmei Li, Jiangbin Luo and Yaojia Jiang

Org. Chem. Front., 2023, 10, 5782
DOI: 10.1039/D3QO01461D

Rh2(ii)-catalyzed enantioselective intramolecular Büchner reaction and aromatic substitution of donor–donor carbenes

Dong Zhu, Tongxiang Cao, Kai Chen and Shifa Zhu

Chem. Sci., 2022, 13, 1992
DOI: 10.1039/D1SC05374D

Catalytic alkane C–H functionalization by carbene insertion into unactivated C(sp3)–H bonds

Yongzhen Pan, Yeming Wang, Swastik Karmakar, Paramasivam Sivaguru and Zhaohong Liu

Org. Chem. Front., 2024, 11, 3777
DOI: 10.1039/D4QO00606B

Alkylcarbene mediated intramolecular alkene cyclopropanation to construct aza[3.1.0] bicycles

Zhen Fu, Chengming Wang and Cong-Ying Zhou

Org. Chem. Front., 2023, 10, 699
DOI: 10.1039/D2QO01532C

Fe-catalyzed B–H and Si–H insertion reactions of gem-dihaloalkanes

Xinyu Wang and Zhaobin Wang

Org. Chem. Front., 2024, 11, 2241
DOI: 10.1039/D4QO00136B

Gold catalysed regio- and chemoselective azo coupling of 1,2- and 1,4-diazoquinones with 1H-indoles

Jianwen Jin, Andrés Felipe León Rojas, Yichao Zhao, Sara Helen Kyne, Bo Xia, Bingwei Zhong and Philip Wai Hong Chan

Org. Chem. Front., 2024, 11, 290
DOI: 10.1039/D3QO01676E

Palladium-catalyzed amination oxidation of electron-rich olefins in green media

Yongpeng Zheng, Yaodan Wu, Jianxiao Li, Wanqing Wu, Shaorong Yang, Chaorong Qi and Huanfeng Jiang

Green Chem., 2025, 27, 1018
DOI: 10.1039/D4GC05771F

Photocatalytic 1,2-oxo-alkylation reaction of styrenes with diazoacetates

Fang Li, Siqi Zhu and Rene M. Koenigs

Chem. Commun., 2022, 58, 7526
DOI: 10.1039/D2CC02414D

Recent advances in the synthesis of nitrogen heterocycles via Rh(iii)-catalyzed chelation-assisted C–H activation/annulation with diazo compounds

Jidan Liu, Ruilian Liang, Qinglian Yan, Liyao Zheng, Zhao-Qing Liu and Shouzhi Pu

Org. Chem. Front., 2025, 12, 3065
DOI: 10.1039/D5QO00111K

Gold(i)-catalyzed redox transformation of o-nitroalkynes with indoles for the synthesis of 2,3′-biindole derivatives

Su Zhou, Qianqian Liu, Ming Bao, Jie Huang, Junjian Wang, Wenhao Hu and Xinfang Xu

Org. Chem. Front., 2021, 8, 1808
DOI: 10.1039/D1QO00134E

[2.2]Paracyclophane-substituted quinolines by skeletal editing strategies

Tilman Köhler, Olaf Fuhr and Stefan Bräse

Org. Chem. Front., 2025, 12, 3546
DOI: 10.1039/D5QO00505A

Migratory insertion of copper-allenylidene from propargyl ester

Qinglin Yao, Boxiang Liu, Tongxiang Cao and Shifa Zhu

Chem. Commun., 2022, 58, 4969
DOI: 10.1039/D2CC00681B

Visible-light-promoted N–H functionalization of O-substituted hydroxamic acid with diazo esters

Shuangshuang Xia, Yongchan Jian, Liwen Zhang, Cheng Zhang, Yuanyuan An and Yubin Wang

RSC Adv., 2023, 13, 14501
DOI: 10.1039/D3RA02407E

Recent advances in transition-metal-free deconstructive functionalization of saturated N-, O-, P-, and S-heterocycles

Pengcheng Li, Jia-Lin Tu and Binbin Huang

Chem. Commun., 2026, 62, 112
DOI: 10.1039/D5CC05893G

Recent advances in metal carbene-induced semipinacol rearrangements

Yang Chen and Shifa Zhu

Chem. Commun., 2024, 60, 11253
DOI: 10.1039/D4CC03252G

Diversity-oriented synthesis of poly-substituted benzofuran derivatives bearing amino groups at 2- or 3-positions: Rh- or Ni-catalyzed cycloisomerization between ynamides and enol ethers

Shohei Ohno, Ray Miyazaki, Tomoyuki Tanaka, Keita Uehara, Jiawei Qiu, Hirona Itakura, Makoto Sako, Kenichi Murai, Jun-ya Hasegawa and Mitsuhiro Arisawa

Org. Chem. Front., 2025, 12, 6026
DOI: 10.1039/D5QO01123J

Diazo compounds: synthesis, carbene generation and reactivity

Hilal Ahmad Khan, Michal Szostak and Chinnappan Sivasankar

Org. Biomol. Chem., 2026, 24, 734
DOI: 10.1039/D5OB01433F

Iron catalysts with N-ligands for carbene transfer of diazo reagents

Caterina Damiano, Paolo Sonzini and Emma Gallo

Chem. Soc. Rev., 2020, 49, 4867
DOI: 10.1039/D0CS00221F

Recent advances in the synthesis of indole embedded heterocycles with 3-diazoindolin-2-imines

Muhammad Suleman, Ping Lu and Yanguang Wang

Org. Chem. Front., 2021, 8, 2059
DOI: 10.1039/D0QO01515F

Iodonium ylides: an emerging and alternative carbene precursor for C–H functionalizations

Sanjeev Kumar, Vaishnavi Borkar, Mohd. Mujahid, Saiprasad Nunewar and Vinaykumar Kanchupalli

Org. Biomol. Chem., 2023, 21, 24
DOI: 10.1039/D2OB01644C

Unlocking novel reaction pathways of diazoalkanes with visible light

Claire Empel, Chao Pei and Rene M. Koenigs

Chem. Commun., 2022, 58, 2788
DOI: 10.1039/D1CC06521A

Recent advances in transition-metal-catalyzed carbene insertion to C–H bonds

Yuan He, Zilong Huang, Kaikai Wu, Juan Ma, Yong-Gui Zhou and Zhengkun Yu

Chem. Soc. Rev., 2022, 51, 2759
DOI: 10.1039/D1CS00895A

Carbenes from cyclopropanated aromatics

Alexander D. Roth and Dasan M. Thamattoor

Org. Biomol. Chem., 2023, 21, 9482
DOI: 10.1039/D3OB01525D

Molybdenum-catalyzed carbonyl–carbonyl olefination reaction for heterocycle syntheses

Yuan-Qing Dong, Xiao-Nan Shi, Li-Ya Cao, Jin Bai and Chun-Xiang Zhuo

Org. Chem. Front., 2023, 10, 3544
DOI: 10.1039/D3QO00567D

Palladium-catalyzed intramolecular enantioselective C(sp3)–H insertion of donor/donor carbenes

Wendeng Li, He Zhang, Kai Chen, Huanfeng Jiang, Jianwei Sun and Shifa Zhu

Chem. Sci., 2022, 13, 12396
DOI: 10.1039/D2SC03524C

Mechanism and stereoselectivity in metal and enzyme catalyzed carbene insertion into X–H and C(sp2)–H bonds

Reena Balhara, Ritwika Chatterjee and Garima Jindal

Chem. Soc. Rev., 2024, 53, 11004
DOI: 10.1039/D4CS00742E

Catalytic synthesis of functionalized amidinesviacobalt-carbene radical coupling with isocyanides and amines

Zheng-Yang Gu, Hui Han, Zi-Yin Li, Shun-Jun Ji and Ji-Bao Xia

Org. Chem. Front., 2021, 8, 1544
DOI: 10.1039/D1QO00063B

Dirhodium: carbene transformations and beyond

Rui Wu, Dong Zhu and Shifa Zhu

Org. Chem. Front., 2023, 10, 2849
DOI: 10.1039/D3QO00400G

Transition metal-catalyzed reactivity of carbenes with boronic acid derivatives for arylation (alkylation) and beyond

Akanksha Babbar, Pokhriyal Yamini, Mohammad Saleem and Dongari Yadagiri

Org. Biomol. Chem., 2023, 21, 7062
DOI: 10.1039/D3OB00904A

Straightforward access to α-carbonyloxy esters and β-keto thioethers from aryldiazoacetates

Naveen Kumar, Ajay Kant Gola and Satyendra Kumar Pandey

Org. Biomol. Chem., 2024, 22, 1624
DOI: 10.1039/D3OB02104A

Dirhodium(ii)-catalysed cycloisomerization of azaenyne: rapid assembly of centrally and axially chiral isoindazole frameworks

Shaotong Qiu, Xiang Gao and Shifa Zhu

Chem. Sci., 2021, 12, 13730
DOI: 10.1039/D1SC04961E

Iron(iii)-catalyzed mono-, di- and tricyanomethylation of primary amines with diazoacetonitrile: construction of α-amino acetonitriles and asymmetric α-amino succinonitriles

Gang Wang, Yu-Heng Zeng, Qian-Yu Jiang, Jia-Yi Chen, Rong Zhou and Huai-Bo Zou

Org. Chem. Front., 2025, 12, 1992
DOI: 10.1039/D4QO02218A

Highly electrophilic silver carbenes

Xiaolong Zhang, Linxuan Li, Paramasivam Sivaguru, Giuseppe Zanoni and Xihe Bi

Chem. Commun., 2022, 58, 13699
DOI: 10.1039/D2CC04845K

Divergent stereochemical outcomes in the insertion of donor/donor carbenes into the C–H bonds of stereogenic centers

Sarah N. Dishman, Croix J. Laconsay, James C. Fettinger, Dean J. Tantillo and Jared T. Shaw

Chem. Sci., 2022, 13, 1030
DOI: 10.1039/D1SC04622E

Photoredox catalysis leading to triazolo-quinoxalinones at room temperature: selectivity of the rate determining step

Roger Monreal-Corona, Emili Besalú, Anna Pla-Quintana and Albert Poater

Org. Biomol. Chem., 2022, 20, 9330
DOI: 10.1039/D2OB01587K

Mechanistic differences between the Ru(ii) and Zn(ii)-catalyzed cross-coupling of cyclopropenes with diazo compounds: a DFT study

Tiantian Liu, Kang Lv and Xiaoguang Bao

Catal. Sci. Technol., 2024, 14, 6917
DOI: 10.1039/D4CY00995A

Copper-catalyzed crosscoupling of vinyl nitrenes and CF3-carbenes to synthesize CF3-2-azadienes

Yongjuan Jiao, Tao Wu, Xinyu Zhang and Yaojia Jiang

Org. Chem. Front., 2024, 11, 67
DOI: 10.1039/D3QO01537H

Borane catalyzed transesterification of tert-butyl esters using α-aryl α-diazoesters

Maying Yan, Lei Xiao, Jiangkun Xiong, Lvnan Jin, Douglas W. Stephan and Jing Guo

Org. Biomol. Chem., 2023, 21, 8279
DOI: 10.1039/D3OB01548C

Nitrile formation via dichlorocarbene insertion into the Si–N bond of Ln(iii) bis(trimethylsilyl)amide complexes

Yangjuan Li and Yu Gong

Chem. Commun., 2022, 58, 12552
DOI: 10.1039/D2CC04538A

Uncommon carbene insertion reactions

Ming-Yao Huang and Shou-Fei Zhu

Chem. Sci., 2021, 12, 15790
DOI: 10.1039/D1SC03328J

An asymmetric three-component reaction of a diazo compound with an alcohol and a seven-membered imine

Xiongda Xie, Ming Bao, Kewei Chen, Xinfang Xu and Wenhao Hu

Org. Chem. Front., 2022, 9, 2102
DOI: 10.1039/D2QO00076H

Dirhodium(ii)-catalyzed regio- and stereoselective cycloisomerization towards 6,5,3-tricyclic skeletons containing vicinal all-carbon quaternary stereocenters

Zurong Xu, Jiajun Lu, Huanfeng Jiang, Rui Wu and Shifa Zhu

Org. Chem. Front., 2024, 11, 5151
DOI: 10.1039/D4QO00998C

Visible-light-induced oxytrifluoromethylthiolation of α-diazo esters

Fei Tan, Jian Yang, Tao Song, Zhangqun Hou, Xiao Huang, Jian Wang, Ling Mei and Hongbo Dong

Green Chem., 2025, 27, 2989
DOI: 10.1039/D4GC05690F

Lithium–bromine exchange reaction on C60: first theoretical proposal of a stable singlet fullerene carbene without the heteroatom

Mengyang Li, Yaoxiao Zhao, Kun Yuan, Yanbo Han, Jie Zhang, Yong Wu, Masahiro Ehara, Shigeru Nagase and Xiang Zhao

Org. Chem. Front., 2021, 8, 1551
DOI: 10.1039/D0QO01589J

Sulfenylcarbenes and sulfenylnitrenes in organic synthesis

Prakash Kafle, Deacon Herndon and Indrajeet Sharma

Chem. Soc. Rev., 2025, 54, 10344
DOI: 10.1039/D5CS00278H

Synthesis of α-cyanato-α′-carbonyl sulfoxonium ylides in water

Qingyao Zhang, Cankun Luo, Ruizhi Lai, Zhiqian Lin, Pengfei Jia, Shuran Xu, Li Guo and Yong Wu

Green Chem., 2023, 25, 7068
DOI: 10.1039/D3GC02683C

Synthesis of 2-furanyl quinolines via zinc-catalyzed cascade cyclization of enynones with anthranils

Yadong Feng, Pu Wang, Chaoyu Wang, Tian Wang and Xiuling Cui

Org. Biomol. Chem., 2026, 24, 1666
DOI: 10.1039/D5OB01994J

An asymmetric oxidative cyclization/Mannich-type addition cascade reaction for direct access to chiral pyrrolidin-3-ones

Su Zhou, Xiongda Xie, Xinxin Xu, Shanliang Dong, Wenhao Hu and Xinfang Xu

Chem. Commun., 2021, 57, 12171
DOI: 10.1039/D1CC04830A

Carbene-induced ring-opening reactions of five-/six-membered cyclic ethers: expanding the frontiers of functional group introduction and molecular architecture construction

Jun Xiao, Dandan Jiang, Xiujuan Wu, Juanhua Li, Kunming Liu, Bin Huang and Wei Wang

Org. Biomol. Chem., 2025, 23, 2024
DOI: 10.1039/D4OB01923G

A visible-light-promoted metal-free approach for N–H insertions by using donor/donor diazo precursors

Yu Zhang, Qiannan Li, Ping Wang, Jinxin Wang, Jingchuan Lin, Dingding Xia, Er-Jun Hao, Xin Luan, Shoubhik Das and Wei-Dong Zhang

Green Chem., 2024, 26, 4600
DOI: 10.1039/D3GC04431A

Multi-functionalization of Rh-carbynoids with alcohols/carbamates and α-propargylic-3-indolymethanols

Jian Luo, Mengchu Zhang, Gengxin Liu, Zhonghui Zhang, Yu Qian and Wenhao Hu

Org. Chem. Front., 2024, 11, 3596
DOI: 10.1039/D4QO00401A

B(C6F5)3-catalyzed cyclopropanation of 3-alkenyl-oxindoles with diazomethanes

Lei Xiao, Lvnan Jin, Yunbo Zhao, Jing Guo and Douglas W. Stephan

Chem. Commun., 2023, 59, 1833
DOI: 10.1039/D2CC06744G

Copper‐Catalyzed Asymmetric Diyne Cyclization via [1,2]‐Stevens‐Type Rearrangement for the Synthesis of Chiral Chromeno[3,4‐c]pyrroles

Feng‐Lin Hong, Chong‐Yang Shi, Pan Hong, Tong‐Yi Zhai, Xin‐Qi Zhu, Xin Lu and Long‐Wu Ye

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202115554

Integrating Olefin Carboamination and Hofmann‐Löffler‐Freytag Reaction by Radical Deconstruction of Hydrazonyl N−N Bond

Si‐Pei Hu, Chen‐Hui Gao, Tu‐Ming Liu, Bing‐Yang Miao, Hong‐Chen Wang, Wei Yu and Bing Han

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202400168

Rh2(II)-Catalyzed Asymmetric Si–H Insertion of α-Alkyl-Donor Carbene from Diynes: Constructing C/Si-Stereocenters by Outcompeting β-H Migration

Rui Wu, Qi-Feng Wang, Haoran Zhang, Shunlong Liu, Kai Chen and Shifa Zhu

ACS Catal., 2025, 15, 21124
DOI: 10.1021/acscatal.5c06981

The Carbene Chemistry of N-Sulfonyl Hydrazones: The Past, Present, and Future

Xiaolong Zhang, Paramasivam Sivaguru, Yongzhen Pan, Nan Wang, Wenjie Zhang and Xihe Bi

Chem. Rev., 2025, 125, 1049
DOI: 10.1021/acs.chemrev.4c00742

Aryl/aryl diazoalkanes in rhodium(II)-catalyzed rearrangements of sulfur ylides

Lennard Kloene, Sripati Jana, Claire Empel, Rene M. Koenigs and Curt Wentrup

Australian Journal of Chemistry, 2023, 76, 25
DOI: 10.1071/CH22168

Silver carbenoids derived from diazo compounds: A historical perspective on challenges and opportunities

Xiaolong Zhang, Zhaohong Liu, Paramasivam Sivaguru and Xihe Bi

Chem Catalysis, 2021, 1, 599
DOI: 10.1016/j.checat.2021.05.001

Controllable Site-Selective Construction of 4- and 5-Hydroxyalkyl-Substituted Imidazoles from Amidines, Ynals, and Water

Wei Liu, Jiaming He, Xiang Liu, Yue Yu, Yongyan Pei, Baofu Zhu and Hua Cao

J. Org. Chem., 2020, 85, 14954
DOI: 10.1021/acs.joc.0c01715

Axial Ligand Enables Synthesis of Allenylsilane through Dirhodium(II) Catalysis

Wendeng Li, Rui Wu, Hao Ruan, Bo Xiao, Xiang Gao, Huanfeng Jiang, Kai Chen, Tian‐Yu Sun and Shifa Zhu

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202409332

Photocatalytic Synthesis of α‐Trifluoromethyl Amidines and α‐Trifluoromethyl Imidates from Isocyanides and Trifluoroacetylsilanes†

Yuan Yao, Gang Zhou, Shanshan Liu, Xiaotian Qi, Xiaoqian He and Xiao Shen

Chin. J. Chem., 2026
DOI: 10.1002/cjoc.70515

Cyclic (Alkyl)(amino)carbenes (CAACs) in Ruthenium Olefin Metathesis

Jennifer Morvan, Marc Mauduit, Guy Bertrand and Rodolphe Jazzar

ACS Catal., 2021, 11, 1714
DOI: 10.1021/acscatal.0c05508

Unlocking the Potential of Less-Stabilized Carbenes in Chemical Synthesis: Chromium-Catalyzed Asymmetric Cyclopropanation

Qiqige Qiqige and Zhaobin Wang

Synlett, 2026, 37, 12
DOI: 10.1055/a-2655-3113

Crystallography of Reactive Intermediates

Anuvab Das, Gerard Pierre Van Trieste and David C. Powers

Comments on Inorganic Chemistry, 2020, 40, 116
DOI: 10.1080/02603594.2020.1747054

Iodine‐ and Bromine‐Promoted Transformations of Pyridotriazoles: General Access to Geminal Diiodo and Dibromo Methylpyridines

Tao Tang, Jing Chen, Ze‐Feng Xu, Shengguo Duan and Chuan‐Ying Li

Asian J Org Chem, 2023, 12
DOI: 10.1002/ajoc.202300026

Enantioselective Multifunctionalization with Rh Carbynoids

Yu Qian, Jie Tang, Xiaoyu Zhou, Jian Luo, Xiaoyan Yang, Zhuofeng Ke and Wenhao Hu

J. Am. Chem. Soc., 2023, 145, 26403
DOI: 10.1021/jacs.3c10460

Cu(I)‐Catalyzed Enantioselective Epoxidation of Aldehydes with α‐Trifluoromethyl Diazosilanes

Weilu Zhang, Suo Chen, Yunxiao Zhang, Shanshan Liu and Xiao Shen

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202422020

Selective Synthesis of Mono- and Bis-Phosphorylated (Dihydro)pyrans via TMSCl-Mediated Cascade Phosphorylation Cycloisomerization of Enynones

Yi-Feng Qiu, Qiang Wang, Jian-He Cao, Dong-Qian Xue, Ming Li, Zheng-Jun Quan, Xi-Cun Wang and Yong-Min Liang

Org. Lett., 2024, 26, 8636
DOI: 10.1021/acs.orglett.4c03397

Rhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening

Rachel J. Ross, Rubaishan Jeyaseelan and Mark Lautens

Org. Lett., 2020, 22, 4838
DOI: 10.1021/acs.orglett.0c01655

Durch sichtbares Licht vermittelte Cycloadditionen von α‐Ketoacylsilanen mit Iminen: Einfache Synthese von β‐Lactamen

Jian‐Heng Ye, Peter Bellotti, Tiffany O. Paulisch, Constantin G. Daniliuc and Frank Glorius

Angewandte Chemie, 2021, 133, 13785
DOI: 10.1002/ange.202102451

Catalytic Intermolecular Deoxygenative Coupling of Carbonyl Compounds with Alkynes by a Cp*Mo(II)-Catalyst

Jia-Le Wang, Guan-Yu Wu, Jian-Nan Luo, Jun-Long Liu and Chun-Xiang Zhuo

J. Am. Chem. Soc., 2024, 146, 5605
DOI: 10.1021/jacs.3c14195

Transition-Metal-Catalyzed Cross-Coupling with Ketones or Aldehydes via N-Tosylhydrazones

Ying Xia and Jianbo Wang

J. Am. Chem. Soc., 2020, 142, 10592
DOI: 10.1021/jacs.0c04445

Rhodium-Catalyzed Allylic C–H Functionalization of Unactivated Alkenes with α-Diazocarbonyl Compounds

Pinki Sihag, Trisha Chakraborty and Masilamani Jeganmohan

Org. Lett., 2023, 25, 1257
DOI: 10.1021/acs.orglett.2c04356

Copper(I)-Catalyzed Enyne Oxidation/Cyclopropanation: Divergent and Enantioselective Synthesis of Cyclopropanes

Wen-Bo Shen, Xiang-Ting Tang, Ting-Ting Zhang, Dong-Can Lv, Dan Zhao, Tong-Fu Su and Lei Meng

Org. Lett., 2021, 23, 1285
DOI: 10.1021/acs.orglett.0c04268

Catalytic Stereoselective 1,2-cis-Furanosylations Enabled by Enynal-Derived Copper Carbenes

Bidhan Ghosh, Adam Alber, Chance W. Lander, Yihan Shao, Kenneth M. Nicholas and Indrajeet Sharma

ACS Catal., 2024, 14, 1037
DOI: 10.1021/acscatal.3c05237

Kinetics of N2 Release from Diazo Compounds: A Combined Machine Learning-Density Functional Theory Study

Kaveh Farshadfar, Arsalan Hashemi, Reza Khakpour and Kari Laasonen

ACS Omega, 2024, 9, 1106
DOI: 10.1021/acsomega.3c07367

[2 + 1] and [2 + 1 + 1] Cyclization: Diversifying Alkenes for Small Carbocycles via Photocatalytically Accessed 1,3-Dielectrophiles

Junseong Jang, Chaewon Kim, Junhwan Won and Seung Youn Hong

J. Am. Chem. Soc., 2026, 148, 5701
DOI: 10.1021/jacs.5c21279

Dark and Light Reactions of Carbenes─Merging Carbene Transfer Reactions with N-Heterocyclic Carbene Catalysis for the Synthesis of Hydroxamic Acid Esters

Bao-Gui Cai, Qian Li, Claire Empel, Lei Li, Rene M. Koenigs and Jun Xuan

ACS Catal., 2022, 12, 11129
DOI: 10.1021/acscatal.2c02875

Isocyanide-Based Multicomponent Reaction: Cascade α-Acyloxylation/Carboxamidation and [3 + 1+1] Cyclization of I(III)/S(VI)-Ylides

Dan-Ting Shen, Wen-Rong Wu, Wen-Xuan Zou, Qiong Hu, Jiaohang Wei, Mei-Zhu Bao, Xiang Liu and Shang-Shi Zhang

Org. Lett., 2024, 26, 6263
DOI: 10.1021/acs.orglett.4c02255

Cu(I)-catalyzed synthesis of spiro[isoquinoline-4,2'-[1,3]oxazin]-3-ones via ring expansion reactions of isoxazoles with 4-diazoisoquinolin-3-ones

Minghui Qi, Muhammad Suleman, Jiale Fan, Ping Lu and Yanguang Wang

Tetrahedron, 2022, 128, 133092
DOI: 10.1016/j.tet.2022.133092

Relativistic effects on dative carbon-coinage metal bond. Evaluation of NHC-MCl (M = Cu, Ag, Au) from relativistic DFT

Alvaro Muñoz-Castro, Desmond MacLeod Carey and Ramiro Arratia-Perez

Polyhedron, 2021, 197, 115020
DOI: 10.1016/j.poly.2021.115020

The Pyridotriazole Works as a Traceless Directing Group: A C–H Activation/Annulation Cascade Reaction with Iodonium Ylides

Guanghui Lv, Qingyao Zhang, Cuimei Zhang, Yuting Chen, Zheng Lin, Ruizhi Lai, Zhongzhen Yang and Yong Wu

Org. Lett., 2023, 25, 4022
DOI: 10.1021/acs.orglett.3c01102

Photocatalyzed [2+1] cyclization of alkenes and silylated trifluorodiazoethanes: facile entry into (difluoromethylene)cyclopropanes

Suo Chen, Yizhi Zhang, Shanshan Liu and Xiao Shen

Sci. China Chem., 2023, 66, 3141
DOI: 10.1007/s11426-023-1676-y

Rapid and Modular Access to All‐Carbon Quaternary Center‐Containing 2,2‐Disubstituted Bicyclo[1.1.1]pentanes via Cyanocarbene Addition to Bicyclo[1.1.0]butanes

Xin‐Yu Gao, Yuanjiu Xiao, Quanxin Peng, Fujian Yang, Daojing Li, Guoqiang Wang, Yu Qian and Jian‐Jun Feng

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202513768

Dispersive Fluorine/Bromine Interactions as Key Selectivity Determinant: Asymmetric Cyclopropanations with 3,3,3-Trifluoro-2-diazopropionate Catalyzed by a Heterochiral-at-The-Metal Centers Dirhodium Paddlewheel Complex

Matthias Peeters, Lucas Marchal, Sofia Lerda, Giovanni Bistoni and Alois Fürstner

J. Am. Chem. Soc., 2026, 148, 1337
DOI: 10.1021/jacs.5c17842

“Sandwich” Diimine‐Copper Catalysts for C−H Functionalization by Carbene Insertion

Kristine Klimovica, Julius X. Heidlas, Irvin Romero, Thanh V. Le and Olafs Daugulis

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202200334

Straightforward Construction and Functionalizations of Nitrogen‐Containing Heterocycles Through Migratory Insertion of Metal‐Carbenes/Nitrenes

Satabdi Bera, Aniruddha Biswas and Rajarshi Samanta

The Chemical Record, 2021, 21, 3411
DOI: 10.1002/tcr.202100061

Iron‐Catalysed Carbene Transfer to Isocyanides as a Platform for Heterocycle Synthesis

Thomas R. Roose, H. Daniel Preschel, Helena Mayo Tejedor, Jasper C. Roozee, Trevor A. Hamlin, Bert U. W. Maes, Eelco Ruijter and Romano V. A. Orru

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202203074

Scandium Triflate Catalyzed Cycloadditions of Vinyl Diazo Compounds and In Situ Formed Naphthoquinone Methides

Yi-Xiao Yin, Jie Zhan, Ren Liu, Pran Gopal Karmaker, Qing Zhou, Wen-Dao Chu and Quan-Zhong Liu

J. Org. Chem., 2025, 90, 6025
DOI: 10.1021/acs.joc.5c00425

Rh-catalyzed asymmetric cyclopropanation of benzofurans with trifluoromethyl N-triftosylhydrazones

Caicai He, Swastik Karmakar, Dandan Wei, Wei Zhao, Xiaolong Zhang and Xihe Bi

Journal of Fluorine Chemistry, 2024, 273, 110237
DOI: 10.1016/j.jfluchem.2023.110237

Asymmetric Radical Cyclopropanation of α,β-Unsaturated Amides with α-Boryl and α-Silyl Dibromomethanes via Cr(II)-Based Metalloradical Catalysis

Xinyu Wang, Zhaoxin Shi, Mingrui Xu, Xiaoyu Lin and Zhaobin Wang

J. Am. Chem. Soc., 2025, 147, 7282
DOI: 10.1021/jacs.4c13269

Selenonium ylides: synthesis, characterization, and applications to photo-induced cyclopropanation reactions

Eiji Yamaguchi, Hisamori Inagawa and Akichika Itoh

Photochem Photobiol Sci, 2022, 21, 813
DOI: 10.1007/s43630-021-00155-2

Radical Cascade Multicomponent Minisci Reactions with Diazo Compounds

Yong-Liang Su, Geng-Xin Liu, Luca De Angelis, Ru He, Ammar Al-Sayyed, Kirk S. Schanze, Wen-Hao Hu, Huang Qiu and Michael P. Doyle

ACS Catal., 2022, 12, 1357
DOI: 10.1021/acscatal.1c05611

TBAI-Catalyzed S–H and N–H Insertion Reactions of α-Diazoesters with Thiophenols and Amines under Metal-Free Conditions

Rongxiang Chen, Guoyang Ma, Yawen Li, Jinju Zhang, Ran Xia, Kai-Kai Wang and Lantao Liu

J. Org. Chem., 2022, 87, 10990
DOI: 10.1021/acs.joc.2c01262

Rhodium(III)-Catalyzed C–H Activation/[5 + 2] Cascade Annulation of Aroyl Hydrazides with Iodonium Ylides for the Synthesis of Seven-Membered Dibenzodiazepinediones

He Li, Tao Chen, Zhiwei Wang, Yuxin Li, Ye Lu, Xinxin Jin, Ning Xu and Jinglin Liu

J. Org. Chem., 2024, 89, 13412
DOI: 10.1021/acs.joc.4c01557

Cobalt(II)–tetraphenylporphyrin-catalysed carbene transfer from acceptor–acceptor iodonium ylides via N-enolate–carbene radicals

Roel F. J. Epping, Mees M. Hoeksma, Eduard O. Bobylev, Simon Mathew and Bas de Bruin

Nat. Chem., 2022, 14, 550
DOI: 10.1038/s41557-022-00905-4

Borane Catalyzed Selective Diazo Cross‐Coupling Towards Pyrazoles

Ayan Dasgupta, Sanjukta Pahar, Rasool Babaahmadi, Lukas Gierlichs, Brian F. Yates, Alireza Ariafard and Rebecca L. Melen

Adv Synth Catal, 2022, 364, 773
DOI: 10.1002/adsc.202101312

Borane-Catalyzed Carbazolation Reactions of Aryldiazoacetates

Feifei He and Rene M. Koenigs

Org. Lett., 2021, 23, 5831
DOI: 10.1021/acs.orglett.1c01982

Palladium-Catalyzed Three-Component Coupling Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol

Lei Zhu, Xiaojian Ren, Yinghua Yu, Pengcheng Ou, Zhi-Xiang Wang and Xueliang Huang

Org. Lett., 2020, 22, 2087
DOI: 10.1021/acs.orglett.0c00579

Cu(I)‐Catalyzed Enantioselective Epoxidation of Aldehydes with α‐Trifluoromethyl Diazosilanes

Weilu Zhang, Suo Chen, Yunxiao Zhang, Shanshan Liu and Xiao Shen

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202422020

The Cascade Reaction Chemistry of Diazo Compounds with Intentionally Designed Alkene to Access Esterified Heterocycles

Shi-Cui Fang, Shao-Qun Cai, Pan-Pan Li, Zhi Yang, Jun-Fei Zhao, Hui-Xin Xiao, Yu-Tong Zhou, Xin-Ran Sun, Shi-Ya He, Fang Liu, Wu Liang, Bin Pan and Fei Du

Org. Lett., 2025, 27, 559
DOI: 10.1021/acs.orglett.4c03987

Proton or Carbene Transfer? On the Dark and Light Reaction of Diazoalkanes with Alcohols

Claire Empel, Chao Pei, Feifei He, Sripati Jana and Rene M. Koenigs

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202104397

Chemoselective Rearrangement Reactions of Sulfur Ylide Derived from Diazoquinones and Allyl/Propargyl Sulfides

Sijia Yan, Junxin Rao and Cong-Ying Zhou

Org. Lett., 2020, 22, 9091
DOI: 10.1021/acs.orglett.0c03493

Carbene Insertion and Furyl Migration Cascade Toward Benzofurans

Tu Zeng, Shiqing Huang, Yingjian Gong, Li Li, Keyi Guo, Shitian Wu, Huiyang Zhan, Shiyu Xu, Xingcan Zhang and Baosheng Li

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202512949

Enantioselective Synthesis of Complex Carbocycles by C–H Insertion of Aryl/Aryl Carbenes

Jose M. Ruiz, Dylan R. Turner, Mingchun Gao, Wentao Guo, Tania Shahvali, Emily Jimenez Andrade, Wang-Yeuk Kong, Beck R. Miller, James C. Fettinger, Matthew S. Sigman, Dean J. Tantillo and Jared T. Shaw

ACS Catal., 2025, 15, 16403
DOI: 10.1021/acscatal.5c04528

Asymmetric multi-component trifunctionalization reactions with α-Halo Rh-carbenes

Xiaoyan Yang, Xiaoyu Zhou, Wenhao Hu and Yu Qian

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-56446-0

Divergent Synthesis of Polycyclic N-Heterocycles via Controllable Cyclization of Divinylallenes Catalyzed by Copper and Gold

Mi Li, Shi-Jie Liu, Kua-Fei Wei, Li-Xia Xie, Dong-Can Lv, Wen-Bo Shen, Hao Tang and Long-Wu Ye

JACS Au, 2025, 5, 4094
DOI: 10.1021/jacsau.5c00760

Advances in Nitrogen-Directed Aromatic Compound ortho-C—H Bond Borylation Catalyzed by Transition Metals

Huanhuan Luo, Na Pei and Jing Zhang

Chinese Journal of Organic Chemistry, 2021, 41, 2990
DOI: 10.6023/cjoc202103013

Phenylhydrazone anions excitation for the photochemical carbonylation of aryl iodides with aldehydes

Lei Shen, Yang Zhang, Linlin Zhang, Chuanwang Liu, Zhixian Ma, Kangjiang Liang and Chengfeng Xia

Chinese Chemical Letters, 2024, 35, 108742
DOI: 10.1016/j.cclet.2023.108742

Anhydrous Carbene Insertion Reactions: A Synthetic Platform for DNA‐Encoded Library

Xiao‐can Su, Wen‐xia Shi, Yue Zhang, Wen‐jie Xiao, Jia‐ying Xue, Xin‐hai Zhu, Ming Yan and Xue‐jing Zhang

Adv Synth Catal, 2024, 366, 285
DOI: 10.1002/adsc.202300844

Copper-Catalyzed Carbonylation Reactions: A Personal Account

Hui-Qing Geng and Xiao-Feng Wu

Synthesis, 2024, 56, 2595
DOI: 10.1055/s-0042-1751542

Photocatalytic Regioselective Difunctionalization of Alkenes with Diazo Compounds and tert-Butyl Nitrite: Access to γ-Oximino Esters

Yantao Liu, Keyong Zhu, Jingjing Zhao and Pan Li

Org. Lett., 2022, 24, 6834
DOI: 10.1021/acs.orglett.2c02749

Hydrogel-mediated hydrogen sulfide delivery: Mechanistic perspectives and therapeutic frontiers

Vivek Pandey, Nikky Sharma, Aditi Sharma and Tejasvi Pandey

Journal of Drug Delivery Science and Technology, 2026, 116, 107889
DOI: 10.1016/j.jddst.2025.107889

Katalysatorkontrollierte stereoselektive Barton‐Kellogg‐Olefinierung

Tanno A. Schmidt and Christof Sparr

Angewandte Chemie, 2021, 133, 24105
DOI: 10.1002/ange.202109519

Accessing Functionalized Furans from Reacting Enynones and Enynals through Furyl Metal Carbenes

Ho‐Jun Cho and Ju Hyun Kim

Asian J Org Chem, 2024, 13
DOI: 10.1002/ajoc.202300616

Theoretical Study on the Copper-Catalyzed ortho-Selective C-H Functionalization of Naphthols with α-Phenyl-α-Diazoesters

Xiaoli Zhu, Xunshen Liu, Fei Xia and Lu Liu

Molecules, 2023, 28, 1767
DOI: 10.3390/molecules28041767

In Situ Observation of Elusive Dirhodium Carbenes and Studies on the Innate Role of Carboxamidate Ligands in Dirhodium Paddlewheel Complexes: A Combined Experimental and Computational Approach

Matthias Peeters, Lorenzo Baldinelli, Markus Leutzsch, Fabio Caló, Alexander A. Auer, Giovanni Bistoni and Alois Fürstner

J. Am. Chem. Soc., 2024, 146, 26466
DOI: 10.1021/jacs.4c09847

Copper/Chiral Phosphoric-Acid-Catalyzed Intramolecular Reductive Isocyanide-Alkene (1 + 2) Cycloaddition: Enantioselective Construction of 2-Azabicyclo[3.1.0]hexanes

Sidi Cheng, Ting Yu, Jing Li, Yingxiang Liang, Shuang Luo and Qiang Zhu

J. Am. Chem. Soc., 2024, 146, 7956
DOI: 10.1021/jacs.4c00989

Diazo compounds: Recent applications in synthetic organic chemistry and beyond

Jianbo Wang

Tetrahedron Letters, 2022, 108, 154135
DOI: 10.1016/j.tetlet.2022.154135

Complete integration of carbene-transfer chemistry into biosynthesis

Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E. K. Baidoo, Qingyun Dan, Yan Chen, Christopher J. Petzold, Trent R. Northen, Paul D. Adams, Douglas S. Clark, Emily P. Balskus, John F. Hartwig, Aindrila Mukhopadhyay and Jay D. Keasling

Nature, 2023, 617, 403
DOI: 10.1038/s41586-023-06027-2

From Serendipity to Rational Design: Heteroleptic Dirhodium Amidate Complexes for Diastereodivergent Asymmetric Cyclopropanation

Fabio Pasquale Caló, Anne Zimmer, Giovanni Bistoni and Alois Fürstner

J. Am. Chem. Soc., 2022, 144, 7465
DOI: 10.1021/jacs.2c02258

Copper-Catalyzed Asymmetric Reaction of Alkenyl Diynes with Styrenes by Formal [3 + 2] Cycloaddition via Cu-Containing All-Carbon 1,3-Dipoles: Access to Chiral Pyrrole-Fused Bridged [2.2.1] Skeletons

Feng-Lin Hong, Yang-Bo Chen, Si-Han Ye, Guang-Yu Zhu, Xin-Qi Zhu, Xin Lu, Rai-Shung Liu and Long-Wu Ye

J. Am. Chem. Soc., 2020, 142, 7618
DOI: 10.1021/jacs.0c01918

Molybdenum‐Catalyzed Deoxygenative Cyclopropanation of 1,2‐Dicarbonyl or Monocarbonyl Compounds

Li‐Ya Cao, Jian‐Nan Luo, Jia‐Sheng Yao, De‐Ku Wang, Yuan‐Qing Dong, Chao Zheng and Chun‐Xiang Zhuo

Angewandte Chemie, 2021, 133, 15382
DOI: 10.1002/ange.202103429

Asymmetric Büchner reaction and arene cyclopropanation via copper-catalyzed controllable cyclization of diynes

Yan-Xin Zheng, Li-Gao Liu, Tian-Qi Hu, Xiao Li, Zhou Xu, Xin Hong, Xin Lu, Bo Zhou and Long-Wu Ye

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-53605-7

Understanding the Chemoselectivity in Palladium-Catalyzed Three-Component Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol

Xiaojian Ren, Lei Zhu, Yinghua Yu, Zhi-Xiang Wang and Xueliang Huang

Org. Lett., 2020, 22, 3251
DOI: 10.1021/acs.orglett.0c01040

Diastereo- and Enantioselective Intramolecular 1,6-C–H Insertion Reaction of Diaryldiazomethanes Catalyzed by Chiral Dirhodium(II) Carboxylates

Masahiro Anada, Shunichi Hashimoto, Motoki Ito, Yuji Kondo, Ryosuke Namie, Yoshihiro Natori, Koji Takeda, Hisanori Nambu and Yasunori Yamamoto

HETEROCYCLES, 2021, 103, 1078
DOI: 10.3987/COM-20-S(K)61

Synthesis of Indeno[1,2-c]furans via Cobalt-Catalyzed Radical–Polar Crossover [3 + 2] Cycloaddition of o-Alkynylaryl β-Dicarbonyls

Guo-Cai Yuan, Peng Guo, Zhi-Hua Wang, Lingyun Zhu, Xinglei He, Yuanming Li and Ke-Yin Ye

Org. Lett., 2022, 24, 8197
DOI: 10.1021/acs.orglett.2c03297

Cobalt-catalyzed N–F bond activation for hydroamination of diazocarbonyl compounds with NFSI

Rongxiang Chen, Bingyang Wu, Wenya Liu, Jutuan Xiao and Kai-Kai Wang

Tetrahedron, 2025, 186, 134895
DOI: 10.1016/j.tet.2025.134895

Understanding the Influence of Donor‐Acceptor Diazo Compounds on the Catalyst Efficiency of B(C6F5)3 Towards Carbene Formation

Rasool Babaahmadi, Ayan Dasgupta, Christopher J. T. Hyland, Brian F. Yates, Rebecca L. Melen and Alireza Ariafard

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202104376

Catalytic Deoxygenative Cyclopropanation of 1,2-Dicarbonyl or Monocarbonyl Compounds via Molybdenum Catalysis

Jia-Le Wang and Chun-Xiang Zhuo

Synlett, 2022, 33, 599
DOI: 10.1055/a-1696-4553

Visible Light‐Induced [3+2] Cyclization Reactions of Hydrazones with Hypervalent Iodine Diazo Reagents for the Synthesis of 1‐Amino‐1,2,3‐Triazoles

Jun‐Ying Dong, He Wang, Shukuan Mao, Xin Wang, Ming‐Dong Zhou and Lei Li

Adv Synth Catal, 2021, 363, 2133
DOI: 10.1002/adsc.202001436

A Platform for the Synthesis of Diverse Phosphonyl and Thiofunctionalized Sulfoxonium Ylides

Wen-Xuan Zou, Qiong Hu, Dan-Ting Shen, Wen-Rong Wu, Jiaohang Wei, Zi-Feng Yang, Mei-Zhu Bao, Xiang Liu and Shang-Shi Zhang

Org. Lett., 2024, 26, 5811
DOI: 10.1021/acs.orglett.4c02000

The Influence of C(sp3)H–Selenium Interactions on the 77Se NMR Quantification of the π‐Accepting Properties of Carbenes

Glen P. Junor, Jan Lorkowski, Cory M. Weinstein, Rodolphe Jazzar, Cezary Pietraszuk and Guy Bertrand

Angewandte Chemie, 2020, 132, 22212
DOI: 10.1002/ange.202010744

Thioether-Directed C4-Selective C–H Acylmethylation of Indoles Using α-Carbonyl Sulfoxonium Ylides

Chandrababu Naidu Kona, Yuji Nishii and Masahiro Miura

Org. Lett., 2020, 22, 4806
DOI: 10.1021/acs.orglett.0c01617

Blue Light-Promoted Formal [4+1]-Annulation of Diazoacetates with o-Aminoacetophenones: Synthesis of Polysubstituted Indolines and Computational Study

Jinzhou Chen, Shuhao Liu, Xinxin Lv, Kemiao Hong, Jinping Lei, Xinfang Xu and Wenhao Hu

J. Org. Chem., 2020, 85, 13920
DOI: 10.1021/acs.joc.0c01974

Photoredox-enabled remote radical group migration: Pathway to 1,7-dicarbonyl compounds from diazoalkanes

Hai-Bing Ye, Ye-Peng Bao, Tian-Yang Liu, Tao Wei, Chen Yang, Qing-An Liu and Jun Xuan

Tetrahedron Chem, 2023, 7, 100040
DOI: 10.1016/j.tchem.2023.100040

Three-Component Synthesis of Isoquinolone Derivatives via Rh(III)-Catalyzed C–H Activation and Tandem Annulation

Zhenke Yang, Jidan Liu, Yuting Li, Jiawen Ding, Liyao Zheng and Zhao-Qing Liu

J. Org. Chem., 2022, 87, 14809
DOI: 10.1021/acs.joc.2c02181

Rhodium-catalyzed directed C–H functionalization of 2-arylindazoles with diazotized Meldrum's acid

Cheng Yuan, Dongdong Chen, Changduo Pan and Jin-Tao Yu

Journal of Organometallic Chemistry, 2021, 951, 122009
DOI: 10.1016/j.jorganchem.2021.122009

Catalytic Generation of o-Quinone Dimethides by a Nondiazo Approach via Donor/Donor Platinum Carbenes

Jun-Jie Hao, Tao Jiang, FuJunyang Wu, Hejiang Luo and Rong-Tao Li

Org. Lett., 2025, 27, 4817
DOI: 10.1021/acs.orglett.5c01508

A New Ligand Design Based on London Dispersion Empowers Chiral Bismuth–Rhodium Paddlewheel Catalysts

Santanu Singha, Michael Buchsteiner, Giovanni Bistoni, Richard Goddard and Alois Fürstner

J. Am. Chem. Soc., 2021, 143, 5666
DOI: 10.1021/jacs.1c01972

Synthesis and reactivity of 4-N-alkylpyridiniumyl/4-N-alkylquinoliniumyl diazoalkanes

Cheng-Xi Li, Yi Li, Zeng-Feng Li, Ya-Xi Li, Yuan Tian, Mei-Hua Shen and Hua-Dong Xu

Tetrahedron Letters, 2025, 161, 155547
DOI: 10.1016/j.tetlet.2025.155547

Generation of Diazomethyl Radicals by Hydrogen Atom Abstraction and Their Cycloaddition with Alkenes

Yong‐Liang Su, Kuiyong Dong, Haifeng Zheng and Michael P. Doyle

Angew Chem Int Ed, 2021, 60, 18484
DOI: 10.1002/anie.202105472

Divergent de novo construction of α-functionalized pyrrole derivatives via coarctate reaction

Zhuwen Wei, Jiayan Chen, Congzhen Xie, Yang Chen and Shifa Zhu

Chinese Chemical Letters, 2024, 35, 109677
DOI: 10.1016/j.cclet.2024.109677

DFT Approach for Predicting 13C NMR Shifts of Atoms Directly Coordinated to Pd

Svetlana A. Kondrashova and Shamil K. Latypov

Organometallics, 2023, 42, 1951
DOI: 10.1021/acs.organomet.3c00186

Transition Metal Catalyzed Insertion Reactions with Donor/Donor Carbenes

Benjamin D. Bergstrom, Leslie A. Nickerson, Jared T. Shaw and Lucas W. Souza

Angew Chem Int Ed, 2021, 60, 6864
DOI: 10.1002/anie.202007001

High‐Throughput Experimentation and Machine Learning‐Assisted Optimization of Iridium‐Catalyzed Cross‐Dimerization of Sulfoxonium Ylides

Yougen Xu, Yadong Gao, Lebin Su, Haiting Wu, Hao Tian, Majian Zeng, Chunqiu Xu, Xinwei Zhu and Kuangbiao Liao

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202313638

Dearomative Cyclopropanation of Naphthols via Cyclopropene Ring‐Opening

Rachel J. Baker, Justin Ching, Teh Ren Hou, Ivan Franzoni and Mark Lautens

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202116171

Rapid and Modular Access to All‐Carbon Quaternary Center‐Containing 2,2‐Disubstituted Bicyclo[1.1.1]pentanes via Cyanocarbene Addition to Bicyclo[1.1.0]butanes

Xin‐Yu Gao, Yuanjiu Xiao, Quanxin Peng, Fujian Yang, Daojing Li, Guoqiang Wang, Yu Qian and Jian‐Jun Feng

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202513768

Palladium-catalyzed allene synthesis enabled by β-hydrogen elimination from sp2-carbon

Ge Zhang, Yi-Kang Song, Fang Zhang, Ze-Jian Xue, Meng-Yao Li, Gui-Shan Zhang, Bin-Bin Zhu, Jing Wei, Chunsen Li, Chen-Guo Feng and Guo-Qiang Lin

Nat Commun, 2021, 12
DOI: 10.1038/s41467-020-20740-w

Photochemische Carbentransferreaktionen von Aryl/Aryldiazoalkanen – Experiment und Theorie**

Sripati Jana, Chao Pei, Claire Empel and Rene M. Koenigs

Angewandte Chemie, 2021, 133, 13380
DOI: 10.1002/ange.202100299

Sc(OTf)3‐Catalyzed Synthesis of 3‐Substituted Lawsones through a Buchner‐Curtius‐Schlotterbeck Reaction

Sailam Sri Gogula, Dasari Vijaya Prasanna, B. Sridhar, Ch. Abraham Lincoln, P. Muralidhar Reddy and B. V. Subba Reddy

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400362

Furan Synthesis via Triplet Sensitization of Acceptor/Acceptor Diazoalkanes

Siqi Zhu, Fang Li, Claire Empel, Sripati Jana, Chao Pei and Rene M. Koenigs

Adv Synth Catal, 2022, 364, 3149
DOI: 10.1002/adsc.202200654

Highly Regio‐, Stereo‐, and Enantioselective Copper‐Catalyzed B−H Bond Insertion of α‐Silylcarbenes: Efficient Access to Chiral Allylic gem‐Silylboranes

Ming‐Yao Huang, Yu‐Tao Zhao, Cheng‐Da Zhang and Shou‐Fei Zhu

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202203343

Biocatalytic activation of diazirines for carbene-transfer reactions

Balázs Pogrányi, William P. Unsworth and Gideon Grogan

Chem, 2022, 8, 1801
DOI: 10.1016/j.chempr.2022.06.019

Rh(II)-Catalyzed Enynal Cycloisomerization for the Generation of Vinyl Carbene: Divergent Access to Polycyclic Heterocycles

Rui Wu, Yang Chen and Shifa Zhu

ACS Catal., 2023, 13, 132
DOI: 10.1021/acscatal.2c04832

Triftosylhydrazone in Single-Atom Skeletal Editing

Zhaohong Liu, Xiaolong Zhang, Paramasivam Sivaguru and Xihe Bi

Acc. Chem. Res., 2025, 58, 130
DOI: 10.1021/acs.accounts.4c00709

Rhodium-Catalyzed [5 + 1 + 2] Reaction of Yne-Vinylcyclopropenes and CO: The Application of Vinylcyclopropenes for Higher-Order Cycloaddition

Zhiqiang Huang and Zhi-Xiang Yu

J. Am. Chem. Soc., 2025, 147, 15947
DOI: 10.1021/jacs.5c02041

Photocatalyzed Dual Strain Release of [1.1.1]Propellane with Diazo Compounds

Jiahao Hu, Xiaobin Yuan, Yufei Li, Xiaoyu Chen, Zaicheng Nie, Mong-Feng Chiou, Yajun Li and Hongli Bao

ACS Catal., 2024, 14, 5481
DOI: 10.1021/acscatal.4c00533

UV Light Is No Longer Required for the Photoactivation of 1,3,4-Oxadiazolines

Katarzyna Orłowska, João V. Santiago, Piotr Krajewski, Kacper Kisiel, Irena Deperasińska, Katarzyna Zawada, Wojciech Chaładaj and Dorota Gryko

ACS Catal., 2023, 13, 1964
DOI: 10.1021/acscatal.2c05319

Electrophile-Induced Reactions of Cross-Conjugated Enynones in the Synthesis of Heterocycles

Alena S. Pankova

Chem Heterocycl Comp, 2020, 56, 829
DOI: 10.1007/s10593-020-02739-9

1,2-Silyl Rearrangement in Gold Carbene Chemistry: Synthesis of Furyl-Decorated Tetrasubstituted Silylallene Derivatives

Patricia García-Martínez and Luis A. López

Org. Lett., 2024, 26, 4695
DOI: 10.1021/acs.orglett.4c01468

Catalytic reactions for enantioselective transfers of donor-substituted carbenes

Ming-Yao Huang and Shou-Fei Zhu

Chem Catalysis, 2022, 2, 3112
DOI: 10.1016/j.checat.2022.10.016

Molybdenum-Catalyzed Intermolecular Deoxygenative Cross-Coupling Reactions of 1,2-Diketones with α-Ketoamides

Yuan-Qing Dong, Kai Wang and Chun-Xiang Zhuo

ACS Catal., 2022, 12, 11428
DOI: 10.1021/acscatal.2c03731

Electron‐Rich Oxycarbenes: New Synthetic and Catalytic Applications beyond Group 6 Fischer Carbene Complexes

Gang Zhou, Zhuanzhuan Guo and Xiao Shen

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202217189

Diastereoselective Synthesis of 4-Hydroxy-2-quinolinones via Formal [2 + 4] Cycloaddition Reactions Using α-Diazo Pyrazoleamides as C2 Synthons

Pei Li, Maoqing Shi, Kaixin Yang, Tongfei Jing, Zhenghui Kang, Wenhao Hu and Yu Qian

Org. Lett., 2024, 26, 5554
DOI: 10.1021/acs.orglett.4c01956

Copper-Catalyzed [4 + 1] Annulation of Enaminothiones with Indoline-Based Diazo Compounds

Zilong Huang, Yuan He, Liandi Wang, Jiying Li, Bao-Hua Xu, Yong-Gui Zhou and Zhengkun Yu

J. Org. Chem., 2022, 87, 4424
DOI: 10.1021/acs.joc.2c00137

Visible‐Light‐Induced, Single‐Metal‐Catalyzed, Directed C−H Functionalization: Metal‐Substrate‐Bound Complexes as Light‐Harvesting Agents

Chao Pei, Claire Empel and Rene M. Koenigs

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202201743

Visible-Light-Mediated Formal Carbene Insertion Reaction: Enantioselective Synthesis of 1,4-Dicarbonyl Compounds Containing All-Carbon Quaternary Stereocenter

Hua Zhang, Zheyuan Wang, Zirui Wang, Yunpeng Chu, Shuncheng Wang and Xin-Ping Hui

ACS Catal., 2022, 12, 5510
DOI: 10.1021/acscatal.2c00064

Copper‐Catalyzed Asymmetric Diyne Cyclization via [1,2]‐Stevens‐Type Rearrangement for the Synthesis of Chiral Chromeno[3,4‐c]pyrroles

Feng‐Lin Hong, Chong‐Yang Shi, Pan Hong, Tong‐Yi Zhai, Xin‐Qi Zhu, Xin Lu and Long‐Wu Ye

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202115554

Rh-Catalyzed [2,3]-Sigmatropic Rearrangement of Alkynyl Carbenes with Allyl Sulfides to Access Sulfide-Substituted 1,5-Enynes

Zhongxue Fang, Yu Wang, Yiming Ma, Xinyue Han, Zhaohong Liu and Yongquan Ning

J. Org. Chem., 2023, 88, 9677
DOI: 10.1021/acs.joc.2c02910

Access to Diverse Carbonyl Compounds by Catalyst‐Free and Photoinduced Aerobic Cleavage of C=N Bonds

Dingding Xia, Weijie Wang, Xike Xu, Yanping Zhu, Qiannan Li, Jinxin Wang, Yu Zhang and Wei‐Dong Zhang

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202402607

Recent Advances in Iron‐Catalyzed Chemical and Enzymatic Carbene‐Transfer Reactions

Parmjeet Kaur and Vikas Tyagi

Adv Synth Catal, 2021, 363, 877
DOI: 10.1002/adsc.202001158

Alkene Cyclopropanation with gem-Dichloroalkanes Catalyzed by (PNN)Co Complexes: Scope and Mechanism

Bin Cao, Guixia Liu and Zheng Huang

ACS Catal., 2024, 14, 12846
DOI: 10.1021/acscatal.4c03059

Exploiting Remarkable Reactivities of Ynamides: Opportunities in Designing Catalytic Enantioselective Reactions

Jian Luo, Guo-Shu Chen, Shu-Jie Chen, Jin-Sheng Yu, Zhao-Dong Li and Yun-Lin Liu

ACS Catal., 2020, 10, 13978
DOI: 10.1021/acscatal.0c04180

Copper-Catalyzed Oxidation of Hydrazones to Diazo Compounds Using Oxygen as the Terminal Oxidant

Wenbin Liu, Jack Twilton, Bo Wei, Maizie Lee, Melissa N. Hopkins, John Bacsa, Shannon S. Stahl and Huw M. L. Davies

ACS Catal., 2021, 11, 2676
DOI: 10.1021/acscatal.1c00264

Visible Light Induced Brønsted Acid Assisted Pd‐Catalyzed Alkyl Heck Reaction of Diazo Compounds and N‐Tosylhydrazones

Ziyan Zhang, Nikita Kvasovs, Anastasiia Dubrovina and Vladimir Gevorgyan

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202110924

Catalytic Asymmetric Deoxygenative Cyclopropanation Reactions by a Chiral Salen-Mo Catalyst

Li-Ya Cao, Jia-Le Wang, Kai Wang, Jiang-Bin Wu, De-Ku Wang, Jia-Min Peng, Jin Bai and Chun-Xiang Zhuo

J. Am. Chem. Soc., 2023, 145, 2765
DOI: 10.1021/jacs.2c12225

Rh(I)-Catalyzed Cascade Carbonylative Cyclization of Propargyl α-Diazoindolacetates for Construction of Carbazoles

Guo-Hao Zhu and Xuefeng Jiang

Org. Lett., 2023, 25, 8077
DOI: 10.1021/acs.orglett.3c03132

Copper-Catalyzed Directed Hydroindolation/Annulation Sequence of Alkynes with Indoles via Copper Carbenes

Guang Ma, Qiu-Yue Cui, Kua-Fei Wei, Xiao-Lei Jiang, Dong-Can Lv, Xiaoping Xue, Xiu-Hong Zhu, Guang-Xin Ru, Xinfeng Xie and Wen-Bo Shen

Org. Lett., 2024, 26, 4945
DOI: 10.1021/acs.orglett.4c01483

Stereoselective Synthesis of Silyl Enol Ethers with Acylsilanes and α,β-Unsaturated Ketones

Ying Liu, Zhihong Zhu, Yunxiao Zhang, Yizhi Zhang, Shanshan Liu and Xiao Shen

Org. Lett., 2024, 26, 5911
DOI: 10.1021/acs.orglett.4c01782

High‐Throughput Experimentation and Machine Learning‐Assisted Optimization of Iridium‐Catalyzed Cross‐Dimerization of Sulfoxonium Ylides

Yougen Xu, Yadong Gao, Lebin Su, Haiting Wu, Hao Tian, Majian Zeng, Chunqiu Xu, Xinwei Zhu and Kuangbiao Liao

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202313638

Silver‐Catalyzed Dearomative Skeletal Editing of Indazoles by Donor Carbene Insertion

Linxuan Li, Hongzhu Chen, Menglin Liu, Qingwen Zhu, Hongru Zhang, Graham de Ruiter and Xihe Bi

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202304227

Photo‐Induced Homologation of Carbonyl Compounds for Iterative Syntheses

Hua Wang, Shun Wang, Vincent George, Galder Llorente and Burkhard König

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202211578

Lantern‐Like Diplatinum(III)‐Catalyzed Redox‐Free Borylation or Silylation of Alkynes

Chuntao Wang, Xianyang Long, Tongxiang Cao and Shifa Zhu

Chin. J. Chem., 2025, 43, 1015
DOI: 10.1002/cjoc.202400896

Selective Cyclopropanation/Aziridination of Olefins Catalyzed by Bis(pyrazolyl)borate Cu(I) Complexes

Qianyi Zhao, Qiu‐Yue Yao, Yan‐Jiao Zhang, Ting Xu, Jie Zhang and Xuenian Chen

Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202200790

MicroED Structure of a Protoglobin Reactive Carbene Intermediate

Emma Danelius, Nicholas J. Porter, Johan Unge, Frances H. Arnold and Tamir Gonen

J. Am. Chem. Soc., 2023, 145, 7159
DOI: 10.1021/jacs.2c12004

Carbene insertion into acyl C-H bonds: Rh(III)-catalyzed cross-coupling of 2-aminobenzaldehydes with conjugated enynones

Yifan Ping, Taiwei Chang and Jianbo Wang

Tetrahedron, 2021, 92, 132274
DOI: 10.1016/j.tet.2021.132274

Recent Advances in Monofluorinated Carbenes, Carbenoids, Ylides, and Related Species

Arturs Sperga and Janis Veliks

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202301851

Dirhodium-Catalyzed Asymmetric Transformations of Alkynes via Carbene Intermediates

Rui Wu, Zurong Xu, Dong Zhu and Shifa Zhu

Acc. Chem. Res., 2025, 58, 799
DOI: 10.1021/acs.accounts.4c00715

Harnessing carbene polarity: Unified catalytic access to donor, neutral, and acceptor carbenes

Khue N. M. Nguyen, Xueling Mo, Bethany M. DeMuynck, Mohamed Elsayed, Jacob J. A. Garwood, Duong T. Ngo, Ilias Khan Rana and David A. Nagib

Science, 2025, 389, 183
DOI: 10.1126/science.adw4177

Site-Selective C–H Benzylation of Alkanes with N-Triftosylhydrazones Leading to Alkyl Aromatics

Zhaohong Liu, Shanshan Cao, Weijie Yu, Jiayi Wu, Fanhua Yi, Edward A. Anderson and Xihe Bi

Chem, 2020, 6, 2110
DOI: 10.1016/j.chempr.2020.06.031

Ligand‐ and Additive‐Free CuCl2‐Catalyzed para‐C−H Alkylation of Aniline Derivatives via Carbene Insertion

Lei Gao, Sheng Liu, Zi‐Chao Wang, Yongjun Mao and Shi‐Liang Shi

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202100723

Catalyst-free photoinduced C(sp3)-C(sp3) bond formation through C-H insertions using non-activated alkanes/ethers

Qiannan Li, Dinggang Wang, Jinxin Wang, Le Zhang, Xike Xu, Xinyu Han, Shoubhik Das, Yu Zhang and Wei-Dong Zhang

Sci. China Chem., 2025, 68, 1937
DOI: 10.1007/s11426-024-2380-4

Triarylborane Catalyzed Carbene Transfer Reactions Using Diazo Precursors

Ayan Dasgupta, Emma Richards and Rebecca L. Melen

ACS Catal., 2022, 12, 442
DOI: 10.1021/acscatal.1c04746

Catalytic Methods for the Transfer of Nonstabilized Carbenes

Emily S. Arnold, Isaiah K. Eckart-Frank and Sidney M. Wilkerson-Hill

ACS Catal., 2026, 16, 5245
DOI: 10.1021/acscatal.5c08715

Visible-Light-Promoted Aerobic Oxyphosphorylation of α-Diazoesters with H-Phosphine Oxides

Hongyan Zhou, Ganggang Wang, Cunhui Wang and Jingya Yang

Org. Lett., 2022, 24, 1530
DOI: 10.1021/acs.orglett.2c00198

Solvent‐free, B(C6F5)3‐Catalyzed S−H Insertion of Thiophenols and Thiols with α‐Diazoesters

Peng Wang, Yulin Gong, Xiaoyu Wang, Yangqing Ren, Lei Wang, Lele Zhai, Huilin Li and Xuegong She

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200465

Assembly of the Tricyclic Core of Alopecurone C by Asymmetric Donor/Donor Carbene C–H Insertion

Yuan-Shin Shiue, Matthew W. Dyer, Noah P. Burlow, Nutthakarn Soisaeng, Kellan N. Lamb, Cristian Soldi, James C. Fettinger, Dean J. Tantillo and Jared T. Shaw

Org. Lett., 2024, 26, 11129
DOI: 10.1021/acs.orglett.4c03863

Dearomative Cyclopropanation of Naphthols via Cyclopropene Ring‐Opening

Rachel J. Baker, Justin Ching, Teh Ren Hou, Ivan Franzoni and Mark Lautens

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202116171

Picolyl and benzyl functionalized biphenyl NHC carbenes and their silver complexes: Sigma donating and antimicrobial properties

Nalluchamy Muniyappan, Geetha Raghuthaman Advaya, Elanseralathan Sujitha and Shahulhameed Sabiah

Journal of Organometallic Chemistry, 2021, 954-955, 122075
DOI: 10.1016/j.jorganchem.2021.122075

Effects of Axial Solvent Coordination to Dirhodium Complexes on the Reactivity and Selectivity in C–H Insertion Reactions: A Computational Study

Croix J. Laconsay, Anna Pla-Quintana and Dean J. Tantillo

Organometallics, 2021, 40, 4120
DOI: 10.1021/acs.organomet.1c00574

Catalytic Epoxidation of Carbonyl Compounds via Carbonyl Ylides: from Racemic to Enantioselective

Lin‐Jun Qi, Bo Zhou and Long‐Wu Ye

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202401389

Gold-Catalyzed Synthesis of Small Rings

Mauro Mato, Allegra Franchino, Cristina Garcı́a-Morales and Antonio M. Echavarren

Chem. Rev., 2021, 121, 8613
DOI: 10.1021/acs.chemrev.0c00697

Carbon-oxygen bond formation via visible-light-induced O–H insertion between acylsilanes and oximes

Bao Gui Cai, Qian Li, Lei Li and Jun Xuan

Green Synthesis and Catalysis, 2022, 3, 194
DOI: 10.1016/j.gresc.2021.12.004

Conformational Locking Induced Enantioselective Diarylcarbene Insertion into B−H and O−H Bonds Using a Cationic Rh(I)/Diene Catalyst

Weici Xu, Takeshi Yamakawa, Meiling Huang, Peilin Tian, Zhigen Jiang and Ming‐Hua Xu

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202412193

Fluorinated Ketones as Trapping Reagents for Visible-Light-Induced Singlet Nucleophilic Carbenes

Daniel L. Priebbenow, Rowan L. Pilkington, Kyle N. Hearn and Anastasios Polyzos

Org. Lett., 2021, 23, 2783
DOI: 10.1021/acs.orglett.1c00708

Chemo‐ and Regioselective Multiple C(sp2)−H Insertions of Malonate Metal Carbenes for Late‐Stage Functionalizations of Azahelicenes

Yana Nikolova, Bibiana Fabri, Pau Moneva Lorente, Alejandro Guarnieri‐Ibáñez, Adiran de Aguirre, Yoshiki Soda, Gennaro Pescitelli, Francesco Zinna, Céline Besnard, Laure Guénée, Dimitri Moreau, Lorenzo Di Bari, Eric Bakker, Amalia I. Poblador‐Bahamonde and Jérôme Lacour

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202210798

Iodine-Mediated Coupling of 2,2,2-Trifluorodiazoethane and Alkynes To Access Bistrifluoromethylated 1,3,5-Trienes

Yangjinxiu Zhou, Tengfei Pang, Yu Liu, Fangrui Zhong and Guojiao Wu

Org. Lett., 2023, 25, 538
DOI: 10.1021/acs.orglett.2c04297

Photochemical Synthesis of Succinic Ester-Containing Phenanthridines from Diazo Compounds as 1,4-Dicarbonyl Precursors

Hai-Bing Ye, Xu-Yu Zhou, Lei Li, Xiang-Kui He and Jun Xuan

Org. Lett., 2022, 24, 6018
DOI: 10.1021/acs.orglett.2c02313

Blue‐Light‐Induced Pd‐Catalyzed Quinolinamide‐Directed Regioselective C‐8 Benzylation of 1‐Naphthylamines Using Flow‐Generated Aryldiazomethanes in Batch and Continuous‐Flow

Wei Zhang, Yanxin Xie, Zaikun Xue, Changqing Miao, Jiao Guo and Baoli Zhao

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202500849

Cu/SaBox‐Catalyzed Photoinduced Coupling of Acylsilanes with Alkynes

Long Zheng, Xueying Guo, Ying‐Chao Li, Yichen Wu, Xiao‐Song Xue and Peng Wang

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202216373

Enantioselective Photochemical Carbene Insertion into C–C and C–H Bonds of 1,3-Diketones by a Guanidine-Amide Organocatalyst

Shiyang Li, Cefei Zhang, Guihua Pan, Liangkun Yang, Zhishan Su, Xiaoming Feng and Xiaohua Liu

ACS Catal., 2023, 13, 4656
DOI: 10.1021/acscatal.3c00192

Gold-catalyzed carbocyclization and imidization of alkyne-tethered diazo compounds with nitrosoarenes for the synthesis of nitrones and naphthalene derivatives

Mengting Liu, Xiongda Xie, Ming Bao, Zhijing Zhang, Wenhao Hu, Yu Qian and Xinfang Xu

Mol Divers, 2023, 27, 1971
DOI: 10.1007/s11030-022-10530-5

O–H Insertion of Hydrogenphosphate Derivatives and α-Diazo Compounds

Fei Tan, Wei Wang, Xiao Huang, Yi Zhong, Tao Song, Jian Wang and Ling Mei

J. Org. Chem., 2024, 89, 2588
DOI: 10.1021/acs.joc.3c02605

Silicon‐Derived Singlet Nucleophilic Carbene Reagents in Organic Synthesis

Daniel L. Priebbenow

Adv Synth Catal, 2020, 362, 1927
DOI: 10.1002/adsc.202000279

A Modular Approach to Dibenzo‐fused ϵ‐Lactams: Palladium‐Catalyzed Bridging‐C−H Activation

Yinghua Yu, Liyao Ma, Jiajin Xia, Luoting Xin, Lei Zhu and Xueliang Huang

Angewandte Chemie, 2020, 132, 18418
DOI: 10.1002/ange.202007799

Transition-Metal Catalyzed Carbene Transformations via Ring Strain-Release Processes

Fukuan Zhang, Hui Wen and Yaojia Jiang

ACS Catal., 2026, 16, 3013
DOI: 10.1021/acscatal.5c09031

Synthesis of atropisomers via transition-metal-catalyzed enantioselective carbene transformations

Chongqing Pan and Zhenhua Gu

Trends in Chemistry, 2023, 5, 684
DOI: 10.1016/j.trechm.2023.05.005

Synthesis of Cyclopropenols Enabled by Visible‐Light‐Induced Organocatalyzed [2+1] Cyclization

Gang Zhou and Xiao Shen

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202115334

Organoelectrocatalysis Enables Direct Cyclopropanation of Methylene Compounds

Liang-Hua Jie, Bin Guo, Jinshuai Song and Hai-Chao Xu

J. Am. Chem. Soc., 2022, 144, 2343
DOI: 10.1021/jacs.1c12762

A DFT Study on the Molecular Mechanism of Additions of Electrophilic and Nucleophilic Carbenes to Non-Enolizable Cycloaliphatic Thioketones

Grzegorz Mlostoń, Karolina Kula and Radomir Jasiński

Molecules, 2021, 26, 5562
DOI: 10.3390/molecules26185562

Post-synthetic metallization in a robust metal-organic framework for efficient B–H bond insertion via enynone-derived carbenes

Lianfen Chen, Jiexun Lin, Bingyi Liu, Yazhao Su, Yanshan Chen, Jian Kang, Yanni Wu, Yifan Chen and Cheng-Xia Chen

Materials Today Chemistry, 2026, 51, 103264
DOI: 10.1016/j.mtchem.2025.103264

Carbene polymerization from the catalyzed decomposition of diazo compounds: Mechanism and modern development

Feifei Li, Longqiang Xiao, Bang Li, Xingyi Hu and Lijian Liu

Coordination Chemistry Reviews, 2022, 473, 214806
DOI: 10.1016/j.ccr.2022.214806

A Carbene Relay Strategy for Cascade Insertion Reactions

Li Li, Chenggang Mi, Guanwang Huang, Meirong Huang, Yuyi Zhu, Shao‐Fei Ni, Zhaofeng Wang and Yong Huang

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202312793

Insights into the Activation Mode of α‐Carbonyl Sulfoxonium Ylides in Rhodium‐Catalyzed C−H Activation: A Theoretical Study

Dianmin Zhang, Xiaofang He, Tao Yang and Song Liu

ChemistryOpen, 2022, 11
DOI: 10.1002/open.202100254

Divergent access to 5,6,7-perifused cycles

Jingpeng Han, Yongjian Yang, Yingjian Gong, Xuan Tang, Yi Tian and Baosheng Li

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-40801-0

Asymmetric Three-Component Reaction of Enynal with Alcohol and Imine as An Expeditious Track to Afford Chiral α-Furyl-β-amino Carboxylate Derivatives

Kemiao Hong, Jirong Shu, Shanliang Dong, Zhijing Zhang, Yicheng He, Mengting Liu, Jingjing Huang, Wenhao Hu and Xinfang Xu

ACS Catal., 2022, 12, 14185
DOI: 10.1021/acscatal.2c04022

Generation and transformation of α-oxy carbene intermediates enabled by copper-catalyzed carbonylation

Yang Yuan and Xiao-Feng Wu

Green Carbon, 2024, 2, 70
DOI: 10.1016/j.greenca.2024.01.002

Visible-light-induced organocatalyzed C(sp2)-H bond functionalization of 1,3-azoles with trifluoroacetylsilanes

Zhengyu Li, Zeguo Zhang, Zhihan Zhang, Gang Zhou, Yizhi Zhang, Shanshan Liu and Xiao Shen

Sci. China Chem., 2024, 67, 3662
DOI: 10.1007/s11426-024-2203-5

The Influence of C(sp3)H–Selenium Interactions on the 77Se NMR Quantification of the π‐Accepting Properties of Carbenes

Glen P. Junor, Jan Lorkowski, Cory M. Weinstein, Rodolphe Jazzar, Cezary Pietraszuk and Guy Bertrand

Angew Chem Int Ed, 2020, 59, 22028
DOI: 10.1002/anie.202010744

Organoelectrocatalytic cyclopropanation of alkenyl trifluoroborates with methylene compounds

Wei Yi, Peng-Cheng Xu, Tianyu He, Shuai Shi and Shenlin Huang

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-54082-8

Rare‐Earth Incorporated Alloy Catalysts: Synthesis, Properties, and Applications

Shuai Zhang, Sandra Elizabeth Saji, Zongyou Yin, Hongbo Zhang, Yaping Du and Chun‐Hua Yan

Advanced Materials, 2021, 33
DOI: 10.1002/adma.202005988

Rh(I)-Catalyzed Modular Synthesis of Axially Chiral Alkylidene Azacycloalkanes

Yang Chen, Jiayan Chen and Shifa Zhu

ACS Cent. Sci., 2025, 11, 899
DOI: 10.1021/acscentsci.5c00232

Rh(I)-Catalyzed Denitrogenative Transformations of 1,2,3-Thiadiazoles: Ligand-Controlled Product Selectivity and the Structure of the Key Organorhodium Intermediate Revealed

Marina A. Tokareva, Indrek Pernik, William Lewis, Barbara A. Messerle, Tatiana V. Glukhareva and Sinead T. Keaveney

ACS Catal., 2022, 12, 5574
DOI: 10.1021/acscatal.2c01175

Synthesis of 1H-Isoindole-Containing Scaffolds Enabled by a Nitrile Trifunctionalization

Àlex Díaz-Jiménez, Roger Monreal-Corona, Miquel Solà, Albert Poater, Anna Roglans and Anna Pla-Quintana

ACS Catal., 2024, 14, 7381
DOI: 10.1021/acscatal.4c00932

Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds

Anthony Abshire, Bukola Ogunyemi and Ampofo Darko

ACS Omega, 2023, 8, 38005
DOI: 10.1021/acsomega.3c03519

Photodriven Radical-Polar Crossover Cyclization Strategy: Synthesis of Pyrazolo[1,5-a]pyridines from Diazo Compounds

Peng Zhao, Yanbo Liu, Yuting Zhang, Lei Wang and Yongmin Ma

Org. Lett., 2024, 26, 2511
DOI: 10.1021/acs.orglett.4c00812

Solvent‐Dependent Etherification of 4‐Hydroxycoumarins with Diazo Esters under Visible‐Light Irradiation

Zixian Yang, Xian Wu, Chengli Xiang, Jin‐Tao Yu and Changduo Pan

Asian J Org Chem, 2023, 12
DOI: 10.1002/ajoc.202300357

Formal Allylation and Enantioselective Cyclopropanation of Donor/Acceptor Rhodium(II) Azavinyl Carbenes

Zhili Liu, Lianfen Chen, Dong Zhu and Shifa Zhu

Org. Lett., 2021, 23, 1275
DOI: 10.1021/acs.orglett.0c04251

Synthesis of Cyclopropenols Enabled by Visible‐Light‐Induced Organocatalyzed [2+1] Cyclization

Gang Zhou and Xiao Shen

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202115334

Sythesis, characterisation, anticancer and antimicrobial activity of Ag-N-heterocyclic carbene complexes containing benzimidazole derivatives

Hüseyin Karci, Muhammed Dündar, Zahid Nawaz, İlknur Özdemir, Nevin Gürbüz, Ahmet Koç, İsmail Özdemir, Lamjed Mansour and Naceur Hamdi

Inorganica Chimica Acta, 2024, 565, 121992
DOI: 10.1016/j.ica.2024.121992

Enantioselective Rh(II)-Catalyzed Desymmetric Cycloisomerization of Diynes: Constructing Furan-Fused Dihydropiperidines with an Alkyne-Substituted Aza-Quaternary Stereocenter

Rui Wu, Jiajun Lu, Tongxiang Cao, Jun Ma, Kai Chen and Shifa Zhu

J. Am. Chem. Soc., 2021, 143, 14916
DOI: 10.1021/jacs.1c07556

Chemo‐ and Regioselective Multiple C(sp2)−H Insertions of Malonate Metal Carbenes for Late‐Stage Functionalizations of Azahelicenes

Yana Nikolova, Bibiana Fabri, Pau Moneva Lorente, Alejandro Guarnieri‐Ibáñez, Adiran de Aguirre, Yoshiki Soda, Gennaro Pescitelli, Francesco Zinna, Céline Besnard, Laure Guénée, Dimitri Moreau, Lorenzo Di Bari, Eric Bakker, Amalia I. Poblador‐Bahamonde and Jérôme Lacour

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202210798

Safe, selective, and scalable carbenes

Michael S. West and Sophie A. L. Rousseaux

Science, 2022, 377, 580
DOI: 10.1126/science.abq8253

Axial Ligand Enables Synthesis of Allenylsilane through Dirhodium(II) Catalysis

Wendeng Li, Rui Wu, Hao Ruan, Bo Xiao, Xiang Gao, Huanfeng Jiang, Kai Chen, Tian‐Yu Sun and Shifa Zhu

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202409332

Visible-Light-Mediated Cyclopropanation Reactions of 3-Diazooxindoles with Arenes

Shuai Zhao, Xiang-Xiang Chen, Nan Gao, Mingcheng Qian and Xin Chen

J. Org. Chem., 2021, 86, 7131
DOI: 10.1021/acs.joc.1c00418

Research Progress on Enantioselective Desymmetrization Reactions Involving Metal Carbenes

Ming-Yu Teng, Tao Han, En-He Huang and Long-Wu Ye

Chinese Journal of Organic Chemistry, 2022, 42, 3295
DOI: 10.6023/cjoc202206041

Carbene B−H Insertion Reactions for C−B Bond Formation

Ximei Zhao, Guanghui Wang and A. Stephen K. Hashmi

ChemCatChem, 2021, 13, 4299
DOI: 10.1002/cctc.202100914

Chemodivergent Synthesis of Oxazoles and Oxime Ethers Initiated by Selective C–N/C–O Formation of Oximes and Diazo Esters

Zhenjie Qi and Shaozhong Wang

Org. Lett., 2021, 23, 8549
DOI: 10.1021/acs.orglett.1c03252

Redrawing the Mannich‐Type Reaction through Carbonyl Umpolung Reactivity

Vittorio Ciccone, Sara Caselli, Giacomo Mari, Fabio Mantellini and Gianfranco Favi

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.70082

Synthetic Strategies toward Lysergic Acid Diethylamide: Ergoline Synthesis via α-Arylation, Borrowing Hydrogen Alkylation, and C–H Insertion

Jeremy R. Tuck, Lee E. Dunlap and David E. Olson

J. Org. Chem., 2023, 88, 13712
DOI: 10.1021/acs.joc.3c01363

Electron‐Rich Oxycarbenes: New Synthetic and Catalytic Applications beyond Group 6 Fischer Carbene Complexes

Gang Zhou, Zhuanzhuan Guo and Xiao Shen

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202217189

Visible-Light-Mediated Energy Transfer Enables Cyclopropanes Bearing Contiguous All-Carbon Quaternary Centers

Dingding Xia, Rongkai Wu, Jinxin Wang, Xinyu Han, Yanchuan Li, Qiannan Li, Xin Luan, Xin Hong, Yu Zhang and Wei-Dong Zhang

ACS Catal., 2023, 13, 9806
DOI: 10.1021/acscatal.3c02350

Visible-light-promoted multi-component carbene transfer reactions of diazo compounds via ring-opening of cyclic ethers

Feng Zhao, Hongyu Ding, Ting Sun, Chao Shen, Zu-Li Wang, Wei Wei and Dong Yi

Chinese Chemical Letters, 2026, 37, 111834
DOI: 10.1016/j.cclet.2025.111834

Chemo‐ and Enantioselective Insertion of Furyl Carbene into the N−H Bond of 2‐Pyridones

Kai Wang, Ziye Liu, Guangyang Xu, Ying Shao, Shengbiao Tang, Ping Chen, Xinhao Zhang and Jiangtao Sun

Angew Chem Int Ed, 2021, 60, 16942
DOI: 10.1002/anie.202104708

A Carbene Relay Strategy for Cascade Insertion Reactions

Li Li, Chenggang Mi, Guanwang Huang, Meirong Huang, Yuyi Zhu, Shao‐Fei Ni, Zhaofeng Wang and Yong Huang

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202312793

Catalysts Based on the C−H⋅⋅⋅M Weak Interaction: Synthesis, Characterization and Catalytic Application of Bis(pyrazolyl)borate Cu(I) Complexes in Carbene Insertion into Heteroatom Hydrogen Bonds

Qianyi Zhao, Qiu‐Yue Yao, Ting Dou, Ting Xu, Jie Zhang and Xuenian Chen

ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202200552

Visible‐Light‐Induced, Single‐Metal‐Catalyzed, Directed C−H Functionalization: Metal‐Substrate‐Bound Complexes as Light‐Harvesting Agents

Chao Pei, Claire Empel and Rene M. Koenigs

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202201743

NHSi/NHGe-Supported Copper Halide and Pseudohalide Complexes: Synthesis and Application

Jabed Hossain, Jishnu Sai Gopinath, Srinu Tothadi, Pattiyil Parameswaran and Shabana Khan

Organometallics, 2022, 41, 3706
DOI: 10.1021/acs.organomet.2c00480

Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp3)-H olefination mediated by donor/donor carbenes

Jiping Hao, Xueying Guo, Shijun He, Zhongliang Xu, Lu Chen, Zhongyu Li, Bichao Song, Jianping Zuo, Zhenyang Lin and Weibo Yang

Nat Commun, 2021, 12
DOI: 10.1038/s41467-021-21484-x

Highly Regio‐, Stereo‐, and Enantioselective Copper‐Catalyzed B−H Bond Insertion of α‐Silylcarbenes: Efficient Access to Chiral Allylic gem‐Silylboranes

Ming‐Yao Huang, Yu‐Tao Zhao, Cheng‐Da Zhang and Shou‐Fei Zhu

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202203343

Brønsted acid‐catalyzed Reactions of Unprotected N‐heterocycles with Aryl/Aryl Diazoalkanes

Srishti Ballabh Bahukhandi, Sripati Jana and Rene M. Koenigs

Asian J Org Chem, 2021, 10, 571
DOI: 10.1002/ajoc.202000709

Divergent Construction of N‐Doped Polycyclic Aromatic Hydrocarbons with Indole as the Nitrogen Source Building Block

Ming Bao, Xiongda Xie, Jingjing Huang, Michael P. Doyle, Zhi Ren, Haibo Yue and Xinfang Xu

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202300140

A Three‐Component Reaction to Construct β‐Aminonitroso‐α‐Diazocarbonyl Compounds under Metal‐Free Conditions

Rongxiang Chen, Jihong Lan, Feng Li, Kai‐Kai Wang, Yinghui Xue, Canran Xu and Lantao Liu

Adv Synth Catal, 2022, 364, 1422
DOI: 10.1002/adsc.202200025

Transition Metal Catalyzed Insertion Reactions with Donor/Donor Carbenes

Benjamin D. Bergstrom, Leslie A. Nickerson, Jared T. Shaw and Lucas W. Souza

Angewandte Chemie, 2021, 133, 6940
DOI: 10.1002/ange.202007001

D4-Symmetric Dirhodium Tetrakis(binaphthylphosphate) Catalysts for Enantioselective Functionalization of Unactivated C–H Bonds

Ziyi Chen, Kristin Shimabukuro, John Bacsa, Djamaladdin G. Musaev and Huw M. L. Davies

J. Am. Chem. Soc., 2024, 146, 19460
DOI: 10.1021/jacs.4c06023

Enantioselective Synthesis of Biscyclopropanes Using Alkynes as Dicarbene Equivalents

Chuntao Wang, Rui Wu, Kai Chen and Shifa Zhu

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202305864

Transition-Metal-Free C–O or C–N Bond Formation Reactions from α-Ketosulfonyl Hydrazones with Alkyl Halides or Amines

Yuan-Qing Dong, Sen Weng, Yu Zhang, Guo-Tong Ruan, Jiao Yang, Shi-Yun Li and Da-Qiu Cui

J. Org. Chem., 2026, 91, 1555
DOI: 10.1021/acs.joc.5c02200

Carbene reactivity from alkyl and aryl aldehydes

Lumin Zhang, Bethany M. DeMuynck, Alyson N. Paneque, Joy E. Rutherford and David A. Nagib

Science, 2022, 377, 649
DOI: 10.1126/science.abo6443

Carbene Insertion and Furyl Migration Cascade Toward Benzofurans

Tu Zeng, Shiqing Huang, Yingjian Gong, Li Li, Keyi Guo, Shitian Wu, Huiyang Zhan, Shiyu Xu, Xingcan Zhang and Baosheng Li

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202512949

Divergent Synthesis of Homoallylic and Allenic Sulfides, Selenides, and S,C-Sulfonium Ylides by Ruthenium Catalysis

Zhiyue He, Li Wu, Yanli Ma, Liting Wen, Xueqing Liu, Wenqian Ding, Wanqi Hu and Xiaowei Wu

Precision Chemistry, 2026, 4, 219
DOI: 10.1021/prechem.5c00098

Synthesis and Isolation of α-Diazophosphonium Ylides

Beiwei Wang, Zhuangzhuang Guo, Laura E. English, Bei He, Maotong Xu, Douglas W. Stephan, Andrew R. Jupp and Tongtong Wang

J. Am. Chem. Soc., 2026, 148, 12495
DOI: 10.1021/jacs.6c01829

Molybdenum‐Catalyzed Deoxygenative Cyclopropanation of 1,2‐Dicarbonyl or Monocarbonyl Compounds

Li‐Ya Cao, Jian‐Nan Luo, Jia‐Sheng Yao, De‐Ku Wang, Yuan‐Qing Dong, Chao Zheng and Chun‐Xiang Zhuo

Angew Chem Int Ed, 2021, 60, 15254
DOI: 10.1002/anie.202103429

Construction of Protoberberine Alkaloid Core through Palladium Carbene Bridging C–H Bond Functionalization and Pyridine Dearomatization

Luoting Xin, Wan Wan, Yinghua Yu, Qiuling Wan, Liyao Ma and Xueliang Huang

ACS Catal., 2021, 11, 1570
DOI: 10.1021/acscatal.0c05156

Who is Who in the Carbene Chemistry of N‐Sulfonyl Hydrazones

Paramasivam Sivaguru, Yongzhen Pan, Nan Wang and Xihe Bi

Chin. J. Chem., 2024, 42, 2071
DOI: 10.1002/cjoc.202300716

Assembling Complex Structures through Cascade and Cycloaddition Processes via Non-Acceptor Gold or Rhodium Carbenes

Helena Armengol-Relats, Mauro Mato, Imma Escofet and Antonio M. Echavarren

Synthesis, 2021, 53, 3991
DOI: 10.1055/a-1535-3215

Stereodivergent Four-Component Reactions via Rh-Carbynoids

Jian Luo, Yinwu Li, Haiqing Wang, Gengxin Liu, Zhenghui Kang, Yu Qian, Zhuofeng Ke, Xiang Fu and Wenhao Hu

J. Am. Chem. Soc., 2025, 147, 19458
DOI: 10.1021/jacs.5c04924

Catalyst‐Controlled Stereoselective Barton–Kellogg Olefination

Tanno A. Schmidt and Christof Sparr

Angew Chem Int Ed, 2021, 60, 23911
DOI: 10.1002/anie.202109519

Triarylboran‐katalysierte Alkenylierungen von Arylestern mit Diazoverbindungen

Ayan Dasgupta, Katarína Stefkova, Rasool Babaahmadi, Lukas Gierlichs, Alireza Ariafard and Rebecca L. Melen

Angewandte Chemie, 2020, 132, 15621
DOI: 10.1002/ange.202007176

Silver-catalyzed site-selective C(sp3)−H benzylation of ethers with N-triftosylhydrazones

Zhaohong Liu, Hongwei Wang, Paramasivam Sivaguru, Steven P. Nolan, Qingmin Song, Weijie Yu, Xinyu Jiang, Edward A. Anderson and Xihe Bi

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-29323-3

Visible‐Light‐Induced Cycloaddition of α‐Ketoacylsilanes with Imines: Facile Access to β‐Lactams

Jian‐Heng Ye, Peter Bellotti, Tiffany O. Paulisch, Constantin G. Daniliuc and Frank Glorius

Angew Chem Int Ed, 2021, 60, 13671
DOI: 10.1002/anie.202102451

Application of Aromatic Substituted 2,2,2-Trifluoro Diazoethanes in Organic Reactions

Cai Zhang

COC, 2022, 26, 639
DOI: 10.2174/1385272826666220516113815

“Sandwich” Diimine‐Copper Catalysts for C−H Functionalization by Carbene Insertion

Kristine Klimovica, Julius X. Heidlas, Irvin Romero, Thanh V. Le and Olafs Daugulis

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202200334

Multicomponent synthesis of α-chloro alkylboronic esters via visible-light-mediated dual catalysis

Bo Li, Ala Bunescu and Matthew J. Gaunt

Chem, 2023, 9, 216
DOI: 10.1016/j.chempr.2022.10.010

Triarylborane‐Catalyzed Alkenylation Reactions of Aryl Esters with Diazo Compounds

Ayan Dasgupta, Katarína Stefkova, Rasool Babaahmadi, Lukas Gierlichs, Alireza Ariafard and Rebecca L. Melen

Angew Chem Int Ed, 2020, 59, 15492
DOI: 10.1002/anie.202007176

Synthesis of Acyl Cyclopentaquinolinones through Simultaneous Construction of the Heterocyclic Scaffold and Introduction of the Acyl Group

Lian Xue, Chang Gao, Xinying Zhang and Xuesen Fan

J. Org. Chem., 2024, 89, 6292
DOI: 10.1021/acs.joc.4c00307

Ligand-controlled divergent asymmetric C(sp3)−H and C(sp3)−O insertion via vinyl cations

Cui-Ting Li, Li-Gao Liu, Jia-Zheng Li, Hao-Xuan Dong, Roman A. Novikov, Ze-Shu Wang, Xin Hong, Bo Zhou and Long-Wu Ye

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-59328-7

Assembly of Complex 1,4‐Cycloheptadienes by (4+3) Cycloaddition of Rhodium(II) and Gold(I) Non‐Acceptor Carbenes

Helena Armengol‐Relats, Mauro Mato and Antonio M. Echavarren

Angewandte Chemie, 2021, 133, 1944
DOI: 10.1002/ange.202012092

Zinc-Catalyzed Asymmetric Cascade Michael/Acyl Transfer Reaction between α-Hydroxy Aryl Ketones and Enynones

Hang Yan, Cui Zhang, Jiao-Jiao Han, Si-Si Du, Yuan-Zhao Hua, Min-Can Wang, Guang-Jian Mei and Shi-Kun Jia

Org. Lett., 2023, 25, 1918
DOI: 10.1021/acs.orglett.3c00446

Silyl Rearrangements in Gold‐Catalyzed Transformations

Patricia García‐Martínez and Luis A. López

Eur J Org Chem, 2026
DOI: 10.1002/ejoc.70392

Platinum(II)-Catalyzed Cyclopropanation of Vinyl Arenes and 1,3-Aryl Dienes Employing Aryl Diazirines as Carbene Precursors

Brady L. Slinger, Miguel Cohen Suarez, Jack C. Malek and Ross A. Widenhoefer

J. Am. Chem. Soc., 2026, 148, 13561
DOI: 10.1021/jacs.5c14354

Visible-Light-Induced Trifluoromethylsulfonylation Reaction of Diazo Compounds Enabled by Manganese Catalysis

Jinrui Bai, Shijia Li, Dan Qi, Zhuoheng Song, Bin Li, Lin Guo, Lijuan Song and Wujiong Xia

Org. Lett., 2023, 25, 2410
DOI: 10.1021/acs.orglett.3c00490

Photoinduced Cross-Coupling Reactions of Diazoalkanes via a Selective Denitrogenation/Cyclization/Addition Cascade for Diversity-Oriented Synthesis of N-Acyl Pyrazolines

Jing Li, Fengya He, Longlong Fang, Jing Zhu, Yiwei Xu, Qinglin Li, Wenyong Li and Chenggui Wu

J. Org. Chem., 2025, 90, 13849
DOI: 10.1021/acs.joc.5c01544

Gold-Catalyzed Regioselective Remote B(9)–H Activation of o-Carboranes with Silylenynones: Access to B(9)-α-Furylsilyl-o-carboranes

Yue Hao, Huiyuan Zheng, Chengrui Hang, Ling Zhi, A. Stephen K. Hashmi, Guanghui Wang and Ximei Zhao

Org. Lett., 2026, 28, 4384
DOI: 10.1021/acs.orglett.6c00507

Photoredox-Catalyzed Cyclopropanation via Ligated Boryl Radical-Mediated Nonstabilized Carbene Formation

Rong-Bin Liang, Chao Yang, Wujiong Xia and Lin Guo

J. Am. Chem. Soc., 2025, 147, 36781
DOI: 10.1021/jacs.5c12677

Silver-Catalyzed Single-Carbon Insertion of Indoles with Acetophenone N-Triftosylhydrazones

Linxuan Li, Hongzhu Chen, Xiaolong Zhang, Karunanidhi Murali, Qingwen Zhu, Menglin Liu, Hongru Zhang, Valentine Nenajdenko and Xihe Bi

Org. Lett., 2024, 26, 7207
DOI: 10.1021/acs.orglett.4c02633

Iron(II) Phthalocyanine-Catalyzed Homodimerization and Tandem Diamination of Diazo Compounds with Primary Amines: Access to Construct Substituted 2,3-Diaminosuccinonitriles in One-Pot

Gang Wang, Jia-Li Yuan, Rong Zhou and Huai-Bo Zou

J. Org. Chem., 2024, 89, 7718
DOI: 10.1021/acs.joc.4c00376

Au(I)-Catalyzed Formal Intermolecular Carbene Insertion into Vinylic C(sp2)–H Bonds and Allylic C(sp3)–H Bonds

Xiao-Yuan Cui, Zhong-Tian Ye, Hai-Hong Wu, Chang-Ge Ji, Feng Zhou and Jian Zhou

ACS Catal., 2023, 13, 1554
DOI: 10.1021/acscatal.2c05351

Visible-Light-Induced Synthesis of 3-Alkyl Chromones under Catalyst- and Additive-Free Conditions

Wei Zhao, Zhiqin He, Xiaohui Yang, Yang Yu, Jonathan B. Baell and Fei Huang

J. Org. Chem., 2023, 88, 13634
DOI: 10.1021/acs.joc.3c01339

An ECEC Mechanism via an Electrophilic Co(II) Carbene in Reductive Cyclopropanation

Bin Cao, Hao-Dong Tan, Guixia Liu, Xuebing Leng, Xiao-Song Xue and Zheng Huang

J. Am. Chem. Soc., 2025, 147, 43640
DOI: 10.1021/jacs.5c13356

Chemo‐ and Enantioselective Insertion of Furyl Carbene into the N−H Bond of 2‐Pyridones

Kai Wang, Ziye Liu, Guangyang Xu, Ying Shao, Shengbiao Tang, Ping Chen, Xinhao Zhang and Jiangtao Sun

Angewandte Chemie, 2021, 133, 17079
DOI: 10.1002/ange.202104708

N-Triftosylhydrazones: A New Chapter for Diazo-Based Carbene Chemistry

Zhaohong Liu, Paramasivam Sivaguru, Giuseppe Zanoni and Xihe Bi

Acc. Chem. Res., 2022, 55, 1763
DOI: 10.1021/acs.accounts.2c00186

Synthesis of Isochromeno[3,4‐d]imidazoles via Rh(II)‐catalyzed [3+2] Annulation between 4‐Diazoisochroman‐3‐imines and Oximes

Minghui Qi, Muhammad Suleman, Yingxiao Wang, Ping Lu and Yanguang Wang

Asian J Org Chem, 2023, 12
DOI: 10.1002/ajoc.202300343

Bottom-up modular synthesis of well-defined oligo(arylfuran)s

Yang Chen, Pingchuan Shen, Tongxiang Cao, Hao Chen, Zujin Zhao and Shifa Zhu

Nat Commun, 2021, 12
DOI: 10.1038/s41467-021-26387-5

Metal Bound or Free Ylides as Reaction Intermediates in Metal-Catalyzed [2,3]-Sigmatropic Rearrangements? It Depends

Croix J. Laconsay and Dean J. Tantillo

ACS Catal., 2021, 11, 829
DOI: 10.1021/acscatal.0c04768

Catalytic Insertion Reactions of α‐Imino Carbenoids

Kuntal Pal and Chandra M. R. Volla

The Chemical Record, 2021, 21, 4032
DOI: 10.1002/tcr.202100238

Synergy of activating substrate and introducing C-H···O interaction to achieve Rh2(II)-catalyzed asymmetric cycloisomerization of 1,n-enynes

Rui Wu, Kai Chen, Jun Ma, Zhi-Xiang Yu and Shifa Zhu

Sci. China Chem., 2020, 63, 1230
DOI: 10.1007/s11426-020-9794-3

Modular Access tometa-Substituted Benzenes via Mo-Catalyzed Intermolecular Deoxygenative Benzene Formation

Yi-Zhe Yu, Jin Bai, Jia-Min Peng, Jia-Sheng Yao and Chun-Xiang Zhuo

J. Am. Chem. Soc., 2023, 145, 8781
DOI: 10.1021/jacs.3c01330

Integrating Olefin Carboamination and Hofmann‐Löffler‐Freytag Reaction by Radical Deconstruction of Hydrazonyl N−N Bond

Si‐Pei Hu, Chen‐Hui Gao, Tu‐Ming Liu, Bing‐Yang Miao, Hong‐Chen Wang, Wei Yu and Bing Han

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202400168

Enantioselective Si–H Insertion Reactions of Diarylcarbenes for the Synthesis of Silicon-Stereogenic Silanes

Jake R. Jagannathan, James C. Fettinger, Jared T. Shaw and Annaliese K. Franz

J. Am. Chem. Soc., 2020, 142, 11674
DOI: 10.1021/jacs.0c04533

Visible-Light-Induced Organocatalyzed [2+1] Cyclization of Alkynes and (Trifluoroacetyl)silanes

Gang Zhou and Xiao Shen

Synlett, 2022, 33, 1575
DOI: 10.1055/a-1840-5199

Rh(II)-Catalyzed C–N Bond Formation Using Enynones and N–H Imines: An Approach to Diarylmethylamines

Ho-Jun Cho, Ye Lim Kim and Ju Hyun Kim

J. Org. Chem., 2022, 87, 16424
DOI: 10.1021/acs.joc.2c02119

Zn‐Catalyzed Cycloisomerization/Methylenation of Enyone with Vinyl Azide: Assembly of Terminal and Deuterated Alkenyl Furan Framework

Shaotong Qiu, Jiangan Liu, Dan Tang, Yangxin Mao, Zhicheng Yang, Changyuan Zhang and Hu Zhou

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.70112

Generation of Diazomethyl Radicals by Hydrogen Atom Abstraction and Their Cycloaddition with Alkenes

Yong‐Liang Su, Kuiyong Dong, Haifeng Zheng and Michael P. Doyle

Angewandte Chemie, 2021, 133, 18632
DOI: 10.1002/ange.202105472

A Modular Approach to Dibenzo‐fused ϵ‐Lactams: Palladium‐Catalyzed Bridging‐C−H Activation

Yinghua Yu, Liyao Ma, Jiajin Xia, Luoting Xin, Lei Zhu and Xueliang Huang

Angew Chem Int Ed, 2020, 59, 18261
DOI: 10.1002/anie.202007799

Skeletal Editing of Alkenes and Alkynes via Single‐Carbon‐Atom Insertion

Wei Jiang, Yaxin Fan, Fukuan Zhang, Mengya Yin, Yu Zhang and Yaojia Jiang

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202501868

Photochemical Carbene Transfer Reactions of Aryl/Aryl Diazoalkanes—Experiment and Theory**

Sripati Jana, Chao Pei, Claire Empel and Rene M. Koenigs

Angew Chem Int Ed, 2021, 60, 13271
DOI: 10.1002/anie.202100299

Cyclopropanation of unactivated alkenes with non-stabilized iron carbenes

Bethany M. DeMuynck, Lumin Zhang, Emma K. Ralph and David A. Nagib

Chem, 2024, 10, 1015
DOI: 10.1016/j.chempr.2024.01.006

Visible-light-mediated deoxygenative transformation of 1,2-dicarbonyl compounds through energy transfer process

Yun-Xuan Luo, Jie Huang, Guojiao Wu, Xiang-Ying Tang and Jin-Ping Qu

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-53635-1

Dirhodium Complexes Heterochiral-at-the-Metal Centers: An Alternative Type of Paddlewheel Catalyst for Asymmetric Synthesis

Matthias Peeters, Lorenzo Baldinelli, Sofia Lerda, Giovanni Bistoni and Alois Fürstner

J. Am. Chem. Soc., 2025, 147, 12418
DOI: 10.1021/jacs.5c03567

tBuOK-Promoted Reaction of Selenocyanates and Hydrazones for the Synthesis of Selenoacetals

Hao Ye, Tingting Ren and Xinxing Wu

Chinese Journal of Organic Chemistry, 2021, 41, 4338
DOI: 10.6023/cjoc202106048

Divergent Synthesis of Enynals and Dihydrobenzo[f]isoquinolines via Deoxyalkynylation of Enaminones Enabled by the Cooperative Action of Tf2O/Pd/Cu

Jianping Lin, Jiakai Tian, Yu Lu, Yiming Xu, Lulu Chen, Yucai Jiang, Mengping Guo, Xiaohan Zhang and Changyuan Zhang

J. Org. Chem., 2024, 89, 16419
DOI: 10.1021/acs.joc.4c01603

Alkynylcarbenes: generation, properties, and application in organic synthesis

V. D. Gvozdev, K. N. Shavrin and M. P. Egorov

Russ Chem Bull, 2024, 74, 1541
DOI: 10.1007/s11172-024-4648-1

Efficient Synthesis of Diaryl Quaternary Centers by Rh(II)/Xantphos Catalyzed Relay C−H Functionalization and Allylic Alkylation

Zhaoliang Ge, Bin Lu, Huailong Teng and Xiaoming Wang

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202202820

Expanded access to vinyldiazo compounds and their catalytic enantioselective applications

Ming Bao, Luca De Angelis, Marlyn S. Rada, Marriah Baird, Hadi Arman, Daniel Wherritt and Michael P. Doyle

Chem Catalysis, 2023, 3, 100778
DOI: 10.1016/j.checat.2023.100778

Synthesis of 2,4-Disubstituted Oxazoles by a Copper-Catalyzed [3+2] Annulation/Olefination Cascade between Amides and IIII/PV Hybrid Ylides

Xingchen Ye and Zhaofeng Wang

Synlett, 2024, 35, 1153
DOI: 10.1055/a-2185-0673

Visible-Light-Initiated Multicomponent Reactions of α-Diazoesters to Access Organophosphorus Compounds

Chengming Qu, Jindong Hao, Hongyu Ding, Yufen lv, Xian-En Zhao, Xiaohui Zhao and Wei Wei

J. Org. Chem., 2022, 87, 12921
DOI: 10.1021/acs.joc.2c01499

Cu/SaBox‐Catalyzed Photoinduced Coupling of Acylsilanes with Alkynes

Long Zheng, Xueying Guo, Ying‐Chao Li, Yichen Wu, Xiao‐Song Xue and Peng Wang

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202216373

Conformational Locking Induced Enantioselective Diarylcarbene Insertion into B−H and O−H Bonds Using a Cationic Rh(I)/Diene Catalyst

Weici Xu, Takeshi Yamakawa, Meiling Huang, Peilin Tian, Zhigen Jiang and Ming‐Hua Xu

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202412193

Chiral rhodium(II)-catalyzed asymmetric aldol-type interception of an oxonium ylide to assemble chiral 2,3-dihydropyrans

Aimin Xu, Xiaoyu Zhou, Rimei Zheng, Zhijing Zhang, Xinru Yin, Kemiao Hong, Zhuofeng Ke, Yu Qian and Wenhao Hu

Sci. China Chem., 2022, 65, 1607
DOI: 10.1007/s11426-022-1275-9

Catalytic Orthogonal Glycosylation Enabled by Enynal‐Derived Copper Carbenes

Surya Pratap Singh, Bidhan Ghosh and Indrajeet Sharma

Adv Synth Catal, 2024, 366, 1847
DOI: 10.1002/adsc.202301207

Fluoroalkyl N-Triftosylhydrazones as Easily Decomposable Diazo Surrogates for Asymmetric [2 + 1] Cycloaddition: Synthesis of Chiral Fluoroalkyl Cyclopropenes and Cyclopropanes

Xinyu Zhang, Chunqi Tian, Zhanjing Wang, Paramasivam Sivaguru, Steven P. Nolan and Xihe Bi

ACS Catal., 2021, 11, 8527
DOI: 10.1021/acscatal.1c01483

Versatile C─H Alkylation and Alkylidenation via Catalytic Alkylidene Transfer of Enones

Yitu Wang, Xiaoke Shou, Yi Xu and Xigeng Zhou

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202502619

Enantioselective Synthesis of Biscyclopropanes Using Alkynes as Dicarbene Equivalents

Chuntao Wang, Rui Wu, Kai Chen and Shifa Zhu

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202305864

Assembly of Complex 1,4‐Cycloheptadienes by (4+3) Cycloaddition of Rhodium(II) and Gold(I) Non‐Acceptor Carbenes

Helena Armengol‐Relats, Mauro Mato and Antonio M. Echavarren

Angew Chem Int Ed, 2021, 60, 1916
DOI: 10.1002/anie.202012092

Paddlewheel dirhodium(II) complexes with N-heterocyclic carbene or phosphine ligand: New reactivity and selectivity

Biqiong Hong, Lei Shi, Lin Li, Shuming Zhan and Zhenhua Gu

Green Synthesis and Catalysis, 2022, 3, 137
DOI: 10.1016/j.gresc.2022.03.001

Rapid Access to Oxabicyclo[2.2.2]octane Skeleton through Cu(I)‐Catalyzed Generation and Trapping of Vinyl‐o‐quinodimethanes (Vinyl‐o‐QDMs)†

Hejiang Luo, Chuan He, Huanfeng Jiang and Shifa Zhu

Chin. J. Chem., 2020, 38, 1052
DOI: 10.1002/cjoc.202000144

Photo‐Induced Homologation of Carbonyl Compounds for Iterative Syntheses

Hua Wang, Shun Wang, Vincent George, Galder Llorente and Burkhard König

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202211578

Synthesis of novel reactive disperse dyes comprising α-phenyl diazo ester groups for polyurethane fiber dyeing

Xiaokang Xie, Lulu Shi, Hua Jiang and Ye Wang

Dyes and Pigments, 2025, 233, 112517
DOI: 10.1016/j.dyepig.2024.112517

Visible Light Induced Brønsted Acid Assisted Pd‐Catalyzed Alkyl Heck Reaction of Diazo Compounds and N‐Tosylhydrazones

Ziyan Zhang, Nikita Kvasovs, Anastasiia Dubrovina and Vladimir Gevorgyan

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202110924

Copper-Catalyzed Direct Carbonylation of Carbenes toward the Synthesis of Propanedioic Acid Derivatives

Hefei Yang, Zhi-Peng Bao, Le-Cheng Wang and Xiao-Feng Wu

Org. Lett., 2023, 25, 1963
DOI: 10.1021/acs.orglett.3c00506

Iron-Catalyzed Intermolecular N–H Insertion Using Acceptor–Acceptor Carbenes Derived from Iodonium Ylides

Àlex Díaz-Jiménez, Nil Insa-Carreras, Anna Roglans, Anna Pla-Quintana and Miquel Costas

Org. Lett., 2025, 27, 7804
DOI: 10.1021/acs.orglett.5c02000

Chiral Magnesium Complex-Catalyzed Asymmetric Cyclization of Vinyl Diazo Compounds with Phenol Derivatives via Noncarbene Pathways

Qin Jiang, Yu-Qin Deng, Xue-Lian Luo, Zhi-Hong Dong, Yao Zhou, Yong Liu, Wen-Dao Chu, Cheng-Yu He, Shiwei Luo and Quan-Zhong Liu

ACS Catal., 2024, 14, 10964
DOI: 10.1021/acscatal.4c02073

Dimethoxyacetaldehyde-N-triftosylhydrazone: Preparation and Carbene Reactivity in Cyclopropanation and Doyle–Kirmse Reactions

Yifan Zhang, Shuang Li, Hongzhu Chen, Wei Song, Yongquan Ning, Zeyun Liu, Yong Wu, Karunanidhi Murali, Paramasivam Sivaguru and Xiaolong Zhang

Org. Lett., 2025, 27, 1941
DOI: 10.1021/acs.orglett.5c00223

Versatile C─H Alkylation and Alkylidenation via Catalytic Alkylidene Transfer of Enones

Yitu Wang, Xiaoke Shou, Yi Xu and Xigeng Zhou

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202502619