Euphorbiaditerpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)

Zha-jun Zhan, Shen Li, Wang Chu and Sheng Yin

Nat. Prod. Rep., 2022, 39, 2132
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Unprecedented diterpenoid dimers with soluble epoxide hydrolase inhibitory effect from Euphorbia fischeriana

Wen-Yu Zhao, Cheng-Peng Sun, Yi-Bo Chang, Wei-Yi Wang, Jian-Kun Yan, Xia Lv, Chao Wang and Xiao-Chi Ma

Org. Biomol. Chem., 2022, 20, 2508
DOI: 10.1039/D2OB00053A

Isolation and biomimetic synthesis of acylphloroglucinol meroterpenoids as anti-breast cancer agents from Dryopteris crassirhizoma

Ping Hai, Zhiqiang Luo, Nie Chen, Huixia Fan, Xudong Wu, Yunqing He, Sihao Deng, Haiyan Jia, Yuan Gao and Jian Yang

Org. Biomol. Chem., 2025, 23, 461
DOI: 10.1039/D4OB01548G

Discovery of two ent-atisane diterpenoid lactones with AChE inhibitory activity from the roots of Euphorbia fischeriana

Jiangchun Wei, Zhiyue Li, Min Shan, Fengzhi Wu, Limin Li, Yucui Ma, Junhong Wu, Xinping Li, Yaqian Liu, Zhengxi Hu, Yonghui Zhang and Zhengzhi Wu

Org. Biomol. Chem., 2023, 21, 6949
DOI: 10.1039/D3OB01007D

Euphorfistrines A-G, cytotoxic and AChE inhibiting triterpenoids from the roots of Euphorbia fischeriana

Jiang-Chun Wei, Hui-Hui Huang, Nan-Fang Zhong, Yu-Ning Gao, Xuan-Li Liu, Guo-Qing Long, Gao-Sheng Hu, An-Hua Wang and Jing-Ming Jia

Bioorganic Chemistry, 2021, 116, 105395
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Bisfischoids A and B, dimeric ent-abietane-type diterpenoids with anti-inflammatory potential from Euphorbia fischeriana Steud.

Cheng-Peng Sun, Yi-Bo Chang, Chao Wang, Xia Lv, Wei-Yu Zhou, Xiang-Ge Tian, Wen-Yu Zhao and Xiao-Chi Ma

Bioorganic Chemistry, 2021, 116, 105356
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Euphorbia Diterpenes: An Update of Isolation, Structure, Pharmacological Activities and Structure–Activity Relationship

Douglas Kemboi, Xavier Siwe-Noundou, Rui W. M. Krause, Moses K. Langat and Vuyelwa Jacqueline Tembu

Molecules, 2021, 26, 5055
DOI: 10.3390/molecules26165055

Diverse gallotannins with α-glucosidase and α-amylase inhibitory activity from the roots of Euphorbia fischeriana steud.

Jia Zhang, Ya-Nan Li, Lin-Bo Guo, Jun He, Peng-Hui Liu, Hai-Yan Tian, Wei-Ku Zhang and Jie-Kun Xu

Phytochemistry, 2022, 202, 113304
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Phytochemical Analysis, Antioxidant Activities In Vitro and In Vivo, and Theoretical Calculation of Different Extracts of Euphorbia fischeriana

Yue Sun, Jia-Xin Feng, Zhong-Bao Wei, Hui Sun, Li Li, Jun-Yi Zhu, Guang-Qing Xia and Hao Zang

Molecules, 2023, 28, 5172
DOI: 10.3390/molecules28135172

Four sesquiterpenoids from the vegetable raw material Schisandra chinensis (Turcz.) Baill.: leaves and stems

Yong-Cheng Yang, Lu-Qi Liu, Kun-Jun Wang, Xue-Qing Zhang, San-Peng Fan, Xiao-Xu Gao, An-Hua Wang, Jing-Ming Jia and Chun-Wang Fu

Natural Product Research, 2022, 36, 5429
DOI: 10.1080/14786419.2021.2013215

Euphorfinoids E-L: Diterpenoids from the roots of Euphorbia fischeriana with acetylcholinesterase inhibitory activity

Jiang-Chun Wei, Xiao-Yu Zhang, Yu-Ning Gao, Dong-Dong Wang, Xue-Lai He, Xiao-Xu Gao, Gao-Sheng Hu, An-Hua Wang and Jing-Ming Jia

Phytochemistry, 2021, 190, 112867
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Integrated Strategy of UHPLC-Q-TOF-MS and Molecular Networking for Identification of Diterpenoids from Euphorbia fischeriana Steud. and Prediction of the Anti-Breast-Cancer Mechanism by the Network Pharmacological Method

Tian-Cheng Ma, Yu-Kun Ma, Jin-Ling Zhang, Lei Liu, Jia Sun, Li-Na Guo, Qi Liu, Yu Sun and Siti Fatimah Sabran

Evidence-Based Complementary and Alternative Medicine, 2021, 2021, 1
DOI: 10.1155/2021/3829434

Biological activities of meroterpenoids isolated from different sources

Neeraj Kumar Fuloria, Radhika K. Raheja, Kaushal H. Shah, Manisha J. Oza, Yogesh A. Kulkarni, Vetriselvan Subramaniyan, Mahendran Sekar and Shivkanya Fuloria

Front. Pharmacol., 2022, 13
DOI: 10.3389/fphar.2022.830103

Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone

M. Eugenia Flores-Giubi, Jose Manuel Botubol-Ares, María J. Durán-Peña, Felipe Escobar-Montaño, David Zorrilla, Jesús Sánchez-Márquez, Eduardo Muñoz, Antonio J. Macías-Sánchez and Rosario Hernández-Galán

Phytochemistry, 2020, 180, 112519
DOI: 10.1016/j.phytochem.2020.112519

Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAFV600E and MEK 1 kinases via in-silico study and ADME prediction

Ahmed F. Essa, Seham S. El-Hawary, Sherif E. Emam, Tahia M. Kubacy, Ezz El-Din A.M. El-Khrisy, Inas Y. Younis and Abdelsamed I. Elshamy

Phytochemistry, 2022, 198, 113154
DOI: 10.1016/j.phytochem.2022.113154

Existing knowledge on Euphorbia fischeriana Steud. (Euphorbiaceae): Traditional uses, clinical applications, phytochemistry, pharmacology and toxicology

Ya-Nan Li, Jun He, Jia Zhang, Ying-Xue Shi, Lin-Bo Guo, Zhong-Can Peng, Ting Yang, Kang Ding, Wei-Ku Zhang and Jie-Kun Xu

Journal of Ethnopharmacology, 2021, 275, 114095
DOI: 10.1016/j.jep.2021.114095

Fischdiabietane A, an Antitumoral Diterpenoid Dimer Featuring an Unprecedented Carbon Skeleton from Euphorbia fischeriana

Jun He, Jie-Kun Xu, Lin-Bo Guo, Cong-Yuan Xia, Wen-Wen Lian, Hai-Yan Tian, Jia Zhang, Ying-Xue Shi and Wei-Ku Zhang

J. Org. Chem., 2021, 86, 5894
DOI: 10.1021/acs.joc.1c00305

Meroterpenoids: A Comprehensive Update Insight on Structural Diversity and Biology

Mamona Nazir, Muhammad Saleem, Muhammad Imran Tousif, Muhammad Aijaz Anwar, Frank Surup, Iftikhar Ali, Daijie Wang, Nilufar Z. Mamadalieva, Elham Alshammari, Mohamed L. Ashour, Ahmed M. Ashour, Ishtiaq Ahmed, Elizbit, Ivan R. Green and Hidayat Hussain

Biomolecules, 2021, 11, 957
DOI: 10.3390/biom11070957

Three new diterpenoids from the roots of Euphorbia fischeriana and their cytotoxicity

Jia Zhang, Jun He, Wei-Feng Yin, Xue-Ge Pan, Hua Yang, Wei-Ku Zhang and Jie-Kun Xu

Fitoterapia, 2024, 178, 106171
DOI: 10.1016/j.fitote.2024.106171