Alanine scan reveals modifiable residues in teixobactin

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Chem. Commun., 2017, 53, 11357
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Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres

Anish Parmar, Abhishek Iyer, Daniel G. Lloyd, Charlotte S. Vincent, Stephen H. Prior, Annemieke Madder, Edward J. Taylor and Ishwar Singh

Chem. Commun., 2017, 53, 7788
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Probing key elements of teixobactin–lipid II interactions in membranes

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Chem. Sci., 2018, 9, 6997
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Synthesis and biological evaluation of novel teixobactin analogues

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Org. Biomol. Chem., 2017, 15, 8755
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Isobactins: O-acyl isopeptide prodrugs of teixobactin and teixobactin derivatives

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Chem. Sci., 2022, 13, 13110
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Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding

Anish Parmar, Abhishek Iyer, Stephen H. Prior, Daniel G. Lloyd, Eunice Tze Leng Goh, Charlotte S. Vincent, Timea Palmai-Pallag, Csanad Z. Bachrati, Eefjan Breukink, Annemieke Madder, Rajamani Lakshminarayanan, Edward J. Taylor and Ishwar Singh

Chem. Sci., 2017, 8, 8183
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Structural studies suggest aggregation as one of the modes of action for teixobactin

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Chem. Sci., 2018, 9, 8850
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Total synthesis of teixobactin and its stereoisomers

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Org. Chem. Front., 2018, 5, 1431
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Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus

Georgina C. Girt, Amit Mahindra, Zaaima J. H. Al Jabri, Megan De Ste Croix, Marco R. Oggioni and Andrew G. Jamieson

Chem. Commun., 2018, 54, 2767
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Synthesis and Stereochemical Determination of the Peptide Antibiotic Novo29

Maj Krumberger, Xingyue Li, Adam G. Kreutzer, Aaron J. Peoples, Anthony G. Nitti, Velia A. Cunningham, Chelsea R. Jones, Catherine Achorn, Losee L. Ling, Dallas E. Hughes and James S. Nowick

J. Org. Chem., 2023, 88, 2214
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Molecular docking analysis of Ficus religiosa L. fruit extracts with HMG-COA reductase inhibitors, anti-hyperlipidemic effects of its in Albino wistar rats, triggered by Triton-X 100 and High fat diet

Shivakumar Inamdar, Makhmur Ahmad, B. Tazneem, Sana Hashmi, Bhagyalakshmi Kulkarni, Bander M. Aldhabi, Ruqaiya Jamal and Mohamad Taleuzzaman

Bioactive Carbohydrates and Dietary Fibre, 2024, 32, 100429
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Emerging peptide antibiotics with therapeutic potential

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Medicine in Drug Discovery, 2021, 9, 100078
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Molecular Dynamics Insight into the Lipid II Recognition by Type A Lantibiotics: Nisin, Epidermin, and Gallidermin

Irina Panina, Amir Taldaev, Roman Efremov and Anton Chugunov

Micromachines, 2021, 12, 1169
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Using chemical synthesis to optimise antimicrobial peptides in the fight against antimicrobial resistance

Freda F. Li and Margaret A. Brimble

Pure and Applied Chemistry, 2019, 91, 181
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X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly

Hyunjun Yang, Michał Wierzbicki, Derek R. Du Bois and James S. Nowick

J. Am. Chem. Soc., 2018, 140, 14028
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Novel High-Throughput Strategy for the Aqueous Solubility Assessment of Peptides and Proteins Exhibiting a Propensity for Gelation: Application to the Discovery of Novel Antibacterial Teixobactin Analogues

Ying Zhang, Daniel Carney, Antoine Henninot and Karthik Srinivasan

Mol. Pharmaceutics, 2021, 18, 469
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New Teixobactin Analogues with a Total Lactam Ring

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ACS Med. Chem. Lett., 2023, 14, 1827
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The Necessity of d-Thr in the New Antibiotic Teixobactin: A Molecular Dynamics Study

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J. Chem. Inf. Model., 2019, 59, 1575
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Unearthing naturally-occurring cyclic antibacterial peptides and their structural optimization strategies

Ping Zeng, Honglan Wang, Pengfei Zhang and Sharon Shui Yee Leung

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Discovery, synthesis, and optimization of teixobactin, a novel antibiotic without detectable bacterial resistance

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Journal of Peptide Science, 2022, 28
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Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP)

Shimaa A. H. Abdel Monaim, Estelle J. Ramchuran, Ayman El-Faham, Fernando Albericio and Beatriz G. de la Torre

J. Med. Chem., 2017, 60, 7476
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Linearized teixobactin is inactive and after sequence enhancement, kills methicillin‐resistant Staphylococcus aureus via a different mechanism

Qianhui Wu, Biswajit Mishra and Guangshun Wang

Peptide Science, 2022, 114
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Thioesterase-Mediated Synthesis of Teixobactin Analogues: Mechanism and Substrate Specificity

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J. Org. Chem., 2018, 83, 7271
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Teixobactin and Its Analogues: A New Hope in Antibiotic Discovery

William D. Fiers, Mark Craighead and Ishwar Singh

ACS Infect. Dis., 2017, 3, 688
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Binding Modes of Teixobactin to Lipid II: Molecular Dynamics Study

Yang Liu, Yaxin Liu, Mary B. Chan-Park and Yuguang Mu

Sci Rep, 2017, 7
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Amino [13]-macrodilactones: Synthesis, derivatization, and structural motifs

Chengsheng Chen, Jean-Marc Lawrence and Mark W. Peczuh

Tetrahedron Letters, 2020, 61, 152579
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Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs

Victor V. Yim, Alan J. Cameron, Iman Kavianinia, Paul W. R. Harris and Margaret A. Brimble

Front. Chem., 2020, 8
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A concise and scalable synthesis of a novel l-allo-enduracididine derivative

Xianwei Sui, Guang Huang, Nameer Ezzat and Yu Yuan

Tetrahedron Letters, 2020, 61, 152148
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Teixobactin as a scaffold for unlimited new antimicrobial peptides: SAR study

Shimaa A.H. Abdel Monaim, Yahya E. Jad, Ayman El-Faham, Beatriz G. de la Torre and Fernando Albericio

Bioorganic & Medicinal Chemistry, 2018, 26, 2788
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Developing Equipotent Teixobactin Analogues against Drug-Resistant Bacteria and Discovering a Hydrophobic Interaction between Lipid II and Teixobactin

Yu Zong, Xiuyun Sun, Hongying Gao, Kirsten J. Meyer, Kim Lewis and Yu Rao

J. Med. Chem., 2018, 61, 3409
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Total synthesis of Met10-teixobactin

Vidya B. Gunjal and D. Srinivasa Reddy

Tetrahedron Letters, 2019, 60, 1909
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The impact of backbone N‐methylation on the structure‐activity relationship of Leu10‐teixobactin

Tony Velkov, James D. Swarbrick, Maytham H. Hussein, Elena K. Schneider‐Futschik, Daniel Hoyer, Jian Li and John A. Karas

Journal of Peptide Science, 2019, 25
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Computer-Aided Drug Design Boosts RAS Inhibitor Discovery

Ge Wang, Yuhao Bai, Jiarui Cui, Zirui Zong, Yuan Gao and Zhen Zheng

Molecules, 2022, 27, 5710
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Synthesis and antibacterial studies of teixobactin analogues with non-isostere substitution of enduracididine

Kang Jin, Kathy Hiu Laam Po, Wang Yeuk Kong, Chung Hei Lo, Chun Wah Lo, Ho Yin Lam, Amaya Sirinimal, Jonathan Avraham Reuven, Sheng Chen and Xuechen Li

Bioorganic & Medicinal Chemistry, 2018, 26, 1062
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Structure–Activity Relationship Studies of the Peptide Antibiotic Clovibactin

Jackson E. H. Brunicardi, James H. Griffin, Michael J. Ferracane, Adam G. Kreutzer, Jeramiah Small, Ana-Teresa Mendoza, Joseph W. Ziller and James S. Nowick

J. Org. Chem., 2024, 89, 12479
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Chemistry and Biology of Teixobactin

Chuchu Guo, Dhanaraju Mandalapu, Xinjian Ji, Jiangtao Gao and Qi Zhang

Chemistry A European J, 2018, 24, 5406
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Environmental and dynamic effects explain how nisin captures membrane-bound lipid II

Irina Panina, Nikolay Krylov, Dmitry Nolde, Roman Efremov and Anton Chugunov

Sci Rep, 2020, 10
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Investigation of the N-Terminus Amino Function of Arg10-Teixobactin

Shimaa A. H. Abdel Monaim, Sikabwe Noki, Estelle J. Ramchuran, Ayman El-Faham, Fernando Albericio and Beatriz G. de la Torre

Molecules, 2017, 22, 1632
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Synthesis and structure−activity relationships of teixobactin

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Annals of the New York Academy of Sciences, 2020, 1459, 86
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Rational Design and Synthesis of Modified Teixobactin Analogues: In Vitro Antibacterial Activity against Staphylococcus aureus, Propionibacterium acnes and Pseudomonas aeruginosa

Vivian Ng, Sarah A. Kuehne and Weng C. Chan

Chemistry A European J, 2018, 24, 9136
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In Vitro Antibacterial Activity of Teixobactin Derivatives on Clinically Relevant Bacterial Isolates

Estelle J. Ramchuran, Anou M. Somboro, Shimaa A. H. Abdel Monaim, Daniel G. Amoako, Raveen Parboosing, Hezekiel M. Kumalo, Nikhil Agrawal, Fernando Albericio, Beatriz G. de La Torre and Linda A. Bester

Front. Microbiol., 2018, 9
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Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)

Ruba Malkawi, Abhishek Iyer, Anish Parmar, Daniel G. Lloyd, Eunice Tze Leng Goh, Edward J. Taylor, Sarir Sarmad, Annemieke Madder, Rajamani Lakshminarayanan and Ishwar Singh

Pharmaceutics, 2018, 10, 183
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Supramolecular Interactions of Teixobactin Analogues in the Crystal State

Hyunjun Yang, Adam G. Kreutzer and James S. Nowick

J. Org. Chem., 2024, 89, 5104
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Synthesis and structure-activity relationship of teixobactin analogues via convergent Ser ligation

Kang Jin, Kathy Hiu Laam Po, Shengxi Wang, Jonathan Avraham Reuven, Chi Nga Wai, Ho Ting Lau, Ting Ho Chan, Sheng Chen and Xuechen Li

Bioorganic & Medicinal Chemistry, 2017, 25, 4990
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In silico approach in reveal traditional medicine plants pharmacological material basis

Fan Yi, Li Li, Li-jia Xu, Hong Meng, Yin-mao Dong, Hai-bo Liu and Pei-gen Xiao

Chin Med, 2018, 13
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Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin

Hyunjun Yang, Arthur V. Pishenko, Xingyue Li and James S. Nowick