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Molecular and Cellular Biology, 2016, 36, 2612
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ACS Synth. Biol., 2014, 3, 280
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RAF kinases are stabilized and required for dendritic cell differentiation and function

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Stabilization of C-RAF:KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF

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Cellular Signalling, 2016, 28, 1451
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Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition

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The EMBO Journal, 2017, 36, 646
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Pan-Raf co-operates with PI3K-dependent signalling and critically contributes to myeloma cell survival independently of mutated RAS

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Lifetime of actin-dependent protein nanoclusters

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Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation

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Angew Chem Int Ed, 2016, 55, 983
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Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers

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Biochemical Journal, 2016, 473, 1719
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Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling

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Neratinib as a Potential Therapeutic for Mutant RAS and Osimertinib-Resistant Tumours

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Recent progress in the identification of BRAF inhibitors as anti-cancer agents

Hala Bakr El-Nassan

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Optogenetic control of signaling in mammalian cells

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HIV-1 Nef-Induced Secretion of the Proinflammatory Protease TACE into Extracellular Vesicles Is Mediated by Raf-1 and Can Be Suppressed by Clinical Protein Kinase Inhibitors

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J Virol, 2021, 95
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Mechanistic model of MAPK signaling reveals how allostery and rewiring contribute to drug resistance

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Molecular Systems Biology, 2023, 19
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Role of Mitogen-Activated Protein (MAP) Kinase Pathways in Metabolic Diseases

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Hidden Targets in RAF Signalling Pathways to Block Oncogenic RAS Signalling

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The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions

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Perspectives of RAS and RHEB GTPase Signaling Pathways in Regenerating Brain Neurons

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IJMS, 2018, 19, 4052
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The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells

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Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

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Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors

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Sci Rep, 2016, 6
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Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents

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European Journal of Medicinal Chemistry, 2018, 158, 144
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Signaling Dynamics Regulating Crosstalks between T-Cell Activation and Immune Checkpoints

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Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions

Adrian Fischer, Bettina Warscheid, Wilfried Weber and Gerald Radziwill

Sci Rep, 2016, 6
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Structural snapshots of RAF kinase interactions

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Biochemical Society Transactions, 2018, 46, 1393
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A-Raf: A new star of the family of raf kinases

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HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells

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Oncotarget, 2016, 7, 6727
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Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation

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Angewandte Chemie, 2016, 128, 995
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Spatial regulation of ARAF controls the MST2-Hippo pathway

Jens Rauch and Walter Kolch

Small GTPases, 2017, 1
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A systematic analysis of signaling reactivation and drug resistance

Boris N. Kholodenko, Nora Rauch, Walter Kolch and Oleksii S. Rukhlenko

Cell Reports, 2021, 35, 109157
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Interactome dynamics of RAF1-BRAF kinase monomers and dimers

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Sci Data, 2023, 10
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Paradoxical oncogenesis—the long-term effects of BRAF inhibition in melanoma

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Nat Rev Clin Oncol, 2013, 10, 390
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