From the journal:

Chemical Communications

Biomimetic nanozymes: bridging natural catalysis and nanomedicine

Yu Xue,a   Yu Fu,a   Hai-Yu Gao,bc   Dong-Yun Zheng,a   Chao Liu,a   Chun-Nan Zhu ORCID logo *a  and  Dong-Bing Cheng ORCID logo *bc  

* Corresponding authors

a College of Biomedical Engineering, Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis & Treatment, and Key Laboratory of Cognitive Science of State Ethnic Affairs Commission, South-Central Minzu University, Wuhan 430074, China
E-mail: cnzhu@mail.scuec.edu.cn

b Hubei Longzhong Laboratory, Wuhan University of Technology Xiangyang Demonstration Zone, Xiangyang, Hubei, China
E-mail: chengdb@whut.edu.cn

c School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, No. 122 Luoshi Road, Wuhan, PR China

Abstract

Biomimetic nanozymes are artificial nanomaterials mimicking natural enzymes. This review summarizes their multi-level design strategies, advanced biomedical applications, and future challenges, with an outlook on integration with AI for rational design of high-performance systems.

Graphical abstract: Biomimetic nanozymes: bridging natural catalysis and nanomedicine

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Article information

DOI
https://doi.org/10.1039/D5CC06708A
Article type
Highlight
Submitted
28 Nov 2025
Accepted
09 Jan 2026
First published
13 Jan 2026

Chem. Commun., 2026, Advance Article

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Biomimetic nanozymes: bridging natural catalysis and nanomedicine

Y. Xue, Y. Fu, H. Gao, D. Zheng, C. Liu, C. Zhu and D. Cheng, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D5CC06708A

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