Venkata M. D. Padmaja, Sachin Jangra and Chandrakumar Appayee
Org. Biomol. Chem., 2019,17, 1714-1717
DOI:
10.1039/C8OB02059K,
Communication
The first α-alkylation of α,β,γ,δ-unsaturated aldehydes is achieved under mild reaction conditions. Several α,β,γ,δ-unsaturated aldehydes and diarylcarbinols are successfully tested for the synthesis of MBH-type α-alkylated products with an excellent regioselectivity. Simple pyrrolidine is efficiently used as a catalyst to achieve a perfect E/Z selectivity of the α-alkylated products.
