Hidetoshi Noda, Yasuko Asada, Masakatsu Shibasaki and Naoya Kumagai
Org. Biomol. Chem., 2019,17, 1813-1816
DOI:
10.1039/C8OB02695E,
Communication
The design, synthesis and photophysical properties of a new fluorogenic probe are described. The structure is based on the recently identified 2,5-diaminopyrimidine (C4N4) fluorophore. The strain-promoted [3 + 2] cycloaddition of the azido-C4N4 probe furnished a triazole that exhibited more than 30-fold enhancement in fluorescence intensity as compared to the azide.
