First synthesis of a C-glycoside anologue of a tumor-associated carbohydrate antigen employing samarium diiodide promoted C-glycosylation

Abstract

A hydrolytically stable analogue of the Tn antigen has been efficiently synthesized for the first time employing a SmI₂-promoted coupling of the pyridyl sulfone of N-acetylgalactosamine with an aldehydoamino acid derivative.

References

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