Themed collection Journal of Materials Chemistry B Recent Review Articles
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A novel surface-enhanced Raman based molecular identification platform for multiplexed and highly accurate clinical diagnosis of viral diseases
Schematic illustration of the E-NoM platform. The workflow for the simultaneous detection of four viral antigens during the infection process.
J. Mater. Chem. B, 2024,12, 7461-7462
https://doi.org/10.1039/D4TB00796D
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In vivo Photopharmacological Inhibition of Hippocampal Activity via Multimodal Probes – Perspective and Opening Steps on Experimental and Computational Challenges
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01117A
Colloidal photonic crystals towards biological applications
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01325E
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Steric protection of near-infrared fluorescent dyes for enhanced bioimaging
Steric protection of a long-wavelength dye, by covalent steric appendage or non-covalent encapsulation, produces enhanced photostability, increased fluorescence brightness, decreased self-aggregation, and superior pharmacokinetic profile.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01281J
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Sculpturing the future of water-soluble cyclodextrin branched polymers in pharmaceutical applications
Versatile water-soluble cyclodextrin polymers can be easily prepared from naturally occurring monomers upon polycondensation in the presence of crosslinking agents. We consider their potential use in combination therapies and the hurdles faced.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01165A
Looking back, moving forward: protein corona of lipid nanoparticles
Intelligent delivery of lipid nanoparticles can be achieved through rational design of protein corona as a “troublemaker”.
J. Mater. Chem. B, 2024,12, 5573-5588
https://doi.org/10.1039/D4TB00186A
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Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds
Advances in bioactive regenerative polymeric scaffolds continue to be made with new materials and methods of characterization.
J. Mater. Chem. B, 2024,12, 2720-2736
https://doi.org/10.1039/D3TB02674D
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Enzymatic micro/nanomotors in biomedicine: from single motors to swarms
Micro/nanomotor swarms propelled by diverse mechanisms.
J. Mater. Chem. B, 2024,12, 2711-2719
https://doi.org/10.1039/D3TB02457A
Intestinal retentive systems – recent advances and emerging approaches
Intestinal retentive devices (IRDs) are devices designed to anchor within the lumen of the intestines for long-term residence in the gastrointestinal tract.
J. Mater. Chem. B, 2024,12, 64-78
https://doi.org/10.1039/D3TB01842C
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Methods to achieve tissue-mimetic physicochemical properties in hydrogels for regenerative medicine and tissue engineering
Hydrogels are limited by their inability to recapitulate native extracellular physicochemical properties. Current efforts using advanced materials science and engineering methods seek to form hydrogels with physiologically-relevant properties.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00716F
Dual-/multi-organelle-targeted AIE probes associated with oxidative stress for biomedical applications
This review summarizes the recent advancements in biomedical applications of dual-/multi-organelle-targeted aggregation-induced emission (AIE) probes, focusing on their in situ induction of oxidative stress.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01440E
Nanomaterial Combined Engineered Bacteria for Intelligent Tumor Immunotherapy
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00741G
Immunologically effective biomaterials enhance immunotherapy of prostate cancer
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D3TB03044J
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Wearable and implantable biosensors: mechanisms and applications in closed-loop therapeutic systems
Biosensors integrated into closed-loop systems provide patient-specific adaptive therapies. These advanced devices have significant potential for managing chronic conditions by continuously adjusting therapeutic regimens based on physiological data.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00782D
Research progress on biodegradable magnesium phosphate ceramics in orthopaedic applications
Magnesium phosphate bioceramics in bone tissue engineering.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01123F
Biomaterials for non-invasive trans-tympanic drug delivery: requirements, recent advances and perspectives
The practice of non-invasive trans-tympanic delivery faces multi-dimensional challenges. Suitable formulation for administration, permeability of the tympanic membrane, pharmacokinetics in middle and inner ear should be considered in design.
J. Mater. Chem. B, 2024,12, 7787-7813
https://doi.org/10.1039/D4TB00676C
Nanomaterials revolutionize biosensing: 0D–3D designs for ultrasensitive detection of microorganisms and viruses
Introducing nanomaterials into biosensors improves the performance of biosensors for faster and more accurate detection of microorganisms and viruses.
J. Mater. Chem. B, 2024,12, 7760-7786
https://doi.org/10.1039/D4TB01077A
Building in vitro models for mechanistic understanding of liver regeneration in chronic liver diseases
The figure shows how impaired regeneration fuels CLD progression. It depicts how 3D bioprinted models can overcome the limitations of animal models and clinical/histopathological data, and provide mechanistic insights into liver regeneration.
J. Mater. Chem. B, 2024,12, 7669-7691
https://doi.org/10.1039/D4TB00738G
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Nanocellulose-based hydrogels as versatile materials with interesting functional properties for tissue engineering applications
Tissue engineering has emerged as a remarkable field aiming to repair or replace damaged tissues through the use of biomimetic constructs.
J. Mater. Chem. B, 2024,12, 7692-7759
https://doi.org/10.1039/D4TB00397G
Nanoparticles constructed from natural polyphenols are used in acute kidney injury
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00837E
Application of metal–organic framework materials in regenerative medicine
Applications of nano-MOFs in bone tissue engineering, wound healing, and others, including periodontitis, tendon repair, nerve repair, and cardiovascular disease. Created with BioRender.com.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00226A
Designing Antibacterial Materials through Simulation and Theory
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01277A
Decellularized extracellular matrix-based bioengineered 3D Breast cancer scaffolds for personalized therapy and drug screening
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00680A
A novel method for the diagnosis of atherosclerosis based on nanotechnology
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00900B
Chitosan-based biomaterials promote bone regeneration by regulating macrophage fate
The development of various osteogenic biomaterials has not only promoted the development of bone tissue engineering but also provided more possibilities for bone defect repair.
J. Mater. Chem. B, 2024,12, 7480-7496
https://doi.org/10.1039/D3TB02563B
Recent adavances of functional modules for tooth regeneration
The use of 3D bioprinting, cell sheet technology, electrostatic droplet technology, and electrospinning technology to generate functional tooth modules represents an emerging and promising approach in dental tissue engineering.
J. Mater. Chem. B, 2024,12, 7497-7518
https://doi.org/10.1039/D4TB01027B
Magneto-responsive biocomposites in wound healing: from characteristics to functions
Schematic illustrations of the pathways through which magneto-responsive biocomposites promote wound healing.
J. Mater. Chem. B, 2024,12, 7463-7479
https://doi.org/10.1039/D4TB00743C
Biomaterials Based on Advanced Oxidation Processes in Tooth Whitening: Fundamental, Progress, and Model
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01311E
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Recent advances on nanomaterial-based glutathione sensors
This review comprehensively covers a wide range of nanomaterial categories, including the fabrication of both chemo- and biosensors, detection methodologies, detection mechanisms, and the applied biological environments for glutathione detection.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01114G
Ion-sensitive field effect transistor biosensors for biomarker detection: current progress and challenges
The ISFET is a label-free, miniaturized, sensitive, and rapid-response sensor for disease screening and monitoring. This review covers its structure, recent researches, challenges, solutions, and future prospects for biomarker measurement.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00719K
Microfluidic-based cardiovascular systems for advanced study of atherosclerosis
This review summarizes the latest advancements in microfluidic-based cardiovascular systems for AS research, encompassing investigations of the underlying pathogenesis and development of diagnostic methods for efficient therapeutic treatments.
J. Mater. Chem. B, 2024,12, 7225-7245
https://doi.org/10.1039/D4TB00756E
DNA functionalized programmable hybrid biomaterials for targeted multiplexed applications
With the advent of DNA nanotechnology, DNA-based biomaterials have emerged as a unique class of materials at the center of various biological advances.
J. Mater. Chem. B, 2024,12, 7267-7291
https://doi.org/10.1039/D4TB00287C
Recent research progress on tumour-specific responsive hydrogels
Exploring novel advancements in hydrogels tailored for tumor-specific responsiveness, promising breakthroughs in cancer treatment.
J. Mater. Chem. B, 2024,12, 7246-7266
https://doi.org/10.1039/D4TB00656A
A comprehensive review on the role of strontium in biodegradable metals
The role of strontium in biodegradable metals.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00779D
Integrated design and application of stimuli-responsive metal–organic frameworks in biomedicine: current status and future perspectives
Various stimuli-responsive MOFs require different triggers and exhibit diverse applications, necessitating the development of biomedical application strategies tailored to specific environments.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00768A
Light-responsive functional nanomaterials as pioneering therapeutics: a paradigm shift to combat age-related disorders
Aging leads to diseases marked by plaque formation, increased senescent cells, and compromised body organ systems. Light-responsive nanomaterials offer a promising therapeutic approach to address the various aspects of age-related pathologies.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00578C
Hydrogels: a promising therapeutic platform for inflammatory skin diseases treatment
Hydrogels revolutionize treating chronic skin diseases by enhancing drug delivery and reducing side effects. This review explores hydrogel design, drug integration, and clinical trials, highlighting their potential to improve efficacy and safety.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00887A
Aggregable gold nanoparticles for cancer photothermal therapy
Photothermal therapy (PTT) is an important non-invasive cancer treatment method.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00403E
Application of a calcium and phosphorus biomineralization strategy in tooth repair: a systematic review
This review summarizes the mechanisms and commonalities of biomineralization and discusses the advancements in dental biomineralization research, guided by insights into calcium and phosphorus mineral biomineralization.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00867G
Advances in biomimetic nanomaterial delivery systems: harnessing nature's inspiration for targeted drug delivery
The properties of nanomaterials make them promising and advantageous for use in drug delivery systems, but challenges arise from the immune system's recognition of exogenous nanoparticles, leading to their clearance and reduced targeting efficiency.
J. Mater. Chem. B, 2024,12, 7001-7019
https://doi.org/10.1039/D4TB00565A
Recent breakthroughs in graphene quantum dot-enhanced sonodynamic and photodynamic therapy
Water-soluble graphene quantum dots (GQDs) have recently exhibited considerable potential for diverse biomedical applications owing to their exceptional optical and chemical properties.
J. Mater. Chem. B, 2024,12, 7041-7062
https://doi.org/10.1039/D4TB00767K
Expanding the boundaries of silk sericin biomaterials in biomedical applications
Unlock the potential of silk sericin (SS) in bioengineering. From its origins to market evolution, explore its diverse applications and future prospects.
J. Mater. Chem. B, 2024,12, 7020-7040
https://doi.org/10.1039/D4TB00386A
Surface functionalization of hydroxyapatite nanoparticles for biomedical applications
This review described the highlight of surface engineering of hydroxyapatite nanoparticles and their interactions with ions and molecules, and summarized how the surface functionalization effectively work in biological situations.
J. Mater. Chem. B, 2024,12, 6805-6826
https://doi.org/10.1039/D4TB00551A
Liquid crystal polymer actuators with complex and multiple actuations
Liquid crystal polymer (LCP) actuators with complex and multiple actuations becomes a hot topic recently. Here, we summarize efforts made for achieving the goals, and furthermore, propose an outlook for LCP actuators with higher intelligence.
J. Mater. Chem. B, 2024,12, 6757-6773
https://doi.org/10.1039/D4TB01055H
A nanoparticle-assisted signal-enhancement technique for lateral flow immunoassays
This review probes the nanoparticle-assisted amplification strategies for lateral flow immunoassay.
J. Mater. Chem. B, 2024,12, 6735-6756
https://doi.org/10.1039/D4TB00865K
Advanced nanomaterials for electrochemical sensors: application in wearable tear glucose sensing technology
The recent applications of nanomaterials in tear fluid electrochemical bio-glucose sensors are systematically reviewed. The challenges, strategies, and prospects for those bio-glucose sensor nanomaterials are also emphasized.
J. Mater. Chem. B, 2024,12, 6774-6804
https://doi.org/10.1039/D4TB00790E
Exogenous MSCs based tissue regeneration: a review of immuno-protection strategies from biomaterial scaffolds
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB00778F
Use of photosensitive molecules in the crosslinking of biopolymers: applications and considerations in biomaterials development
The photophysics and photochemical aspects of different photosensitive molecules (photosensitizers and photoinitiators) employed for biopolymers’ crosslinking and their biological impact in developing biomaterials are reviewed.
J. Mater. Chem. B, 2024,12, 6550-6562
https://doi.org/10.1039/D4TB00299G
Progress in ultrasmall ferrite nanoparticles enhanced T1 magnetic resonance angiography
Schematic diagram of design, regulation, and application of UFNPs.
J. Mater. Chem. B, 2024,12, 6521-6531
https://doi.org/10.1039/D4TB00803K
Advances in drug delivery-based therapeutic strategies for renal fibrosis treatment
Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global health hazard.
J. Mater. Chem. B, 2024,12, 6532-6549
https://doi.org/10.1039/D4TB00737A
Advancements in electrochemical biosensing of cardiovascular disease biomarkers
Cutting-edge electrochemical biosensing techniques for detecting key cardiovascular disease biomarkers utilizing various technologies are explored.
J. Mater. Chem. B, 2024,12, 6305-6327
https://doi.org/10.1039/D4TB00333K
Advances and perspectives in phototherapy-based combination therapy for cancer treatment
Combining phototherapy with treatments such as chemotherapy and immunotherapy enhances efficacy. This review summarizes strategies, analyzes effects, and discusses future directions in combinational cancer therapies.
J. Mater. Chem. B, 2024,12, 6285-6304
https://doi.org/10.1039/D4TB00483C
Innovative approaches to wound healing: insights into interactive dressings and future directions
The objective of this review is to provide an up-to-date and all-encompassing account of the recent advancements in the domain of interactive wound dressings.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D3TB02912C
Advances in skin gene therapy: utilizing innovative dressing scaffolds for wound healing, a comprehensive review
Gene-activated matrices are versatile and novel technologies to treat skin wounds. This approach offers a promising avenue for targeted treatment strategies in skin health care.
J. Mater. Chem. B, 2024,12, 6033-6062
https://doi.org/10.1039/D4TB00966E
Recent advances in injectable hydrogel therapies for periodontitis
Schematic illustration of injectable hydrogels in periodontitis treatment.
J. Mater. Chem. B, 2024,12, 6005-6032
https://doi.org/10.1039/D3TB03070A
Dissolving microneedles for transdermal drug delivery in cancer immunotherapy
Dissolving microneedles mediated immunotherapeutics delivery for cancer treatment.
J. Mater. Chem. B, 2024,12, 5812-5822
https://doi.org/10.1039/D4TB00659C
Recent advances in stimuli-responsive controlled release systems for neuromodulation
Stimuli-responsive controlled release systems are emerging as powerful tools for precise neuromodulation. This review summarizes the recent progress in different release mechanisms and provides insights into future research direction.
J. Mater. Chem. B, 2024,12, 5769-5786
https://doi.org/10.1039/D4TB00720D
Nanoparticles targeting the adenosine pathway for cancer immunotherapy
Outline of this review on adenosine pathway inhibitors for cancer immunotherapy.
J. Mater. Chem. B, 2024,12, 5787-5811
https://doi.org/10.1039/D4TB00292J
Recent advancements in bio-based dielectric and piezoelectric polymers and their biomedical applications
Bio-based polymers possess distinctive dielectric and piezoelectric properties that make them extremely attractive in a variety of biomedical applications.
J. Mater. Chem. B, 2024,12, 5272-5298
https://doi.org/10.1039/D4TB00231H
Cellular elasticity in cancer: a review of altered biomechanical features
The behavior of cancer cell elasticity is modulated by biological, chemical, and physical changes, which in turn have the potential to alter cellular elasticity, and this may be an encouraging prediction for the future discovery of cancer therapies.
J. Mater. Chem. B, 2024,12, 5299-5324
https://doi.org/10.1039/D4TB00328D
Recent advances in synergistic use of GQD-based hydrogels for bioimaging and drug delivery in cancer treatment
Hydrogel loaded GQDs can be used for targeted bioimaging in specific diseases, including cancer, due to their small size and biocompatibility. GQDs have potential for application in cancer therapy and ability to absorb radiation to make them suitable for photothermal and photodynamic therapies.
J. Mater. Chem. B, 2024,12, 5039-5060
https://doi.org/10.1039/D4TB00024B
Recent progress of UCNPs–MoS2 nanocomposites as a platform for biological applications
Research progress of the UCNPs–MoS2 nanoplatform in biological applications such as biosensing, phototherapy, bioimaging, and targeted drug delivery.
J. Mater. Chem. B, 2024,12, 5024-5038
https://doi.org/10.1039/D3TB02958A
Recent advances in micro/nanomotors for antibacterial applications
Currently, the rapid spread of multidrug-resistant bacteria derived from the indiscriminate use of traditional antibiotics poses a significant threat to public health worldwide.
J. Mater. Chem. B, 2024,12, 5000-5023
https://doi.org/10.1039/D3TB02718J
Antimicrobial therapy based on self-assembling peptides
This paper describes the antimicrobial activity of self-assembled peptides, research progress and assembly strategies.
J. Mater. Chem. B, 2024,12, 5061-5075
https://doi.org/10.1039/D4TB00260A
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Lipid nanoparticles as the drug carrier for targeted therapy of hepatic disorders
This paper provides a comprehensive review of the structure, composition, and applications of LNPs in the treatment of hepatic disorders and offers insights into prospects and challenges in the future development of LNPs.
J. Mater. Chem. B, 2024,12, 4759-4784
https://doi.org/10.1039/D3TB02766J
Review of NIR-responsive ‘‘Smart’’ carriers for photothermal chemotherapy
This review focuses on the versatile applications of near-infrared (NIR)-responsive smart carriers in biomedical applications, particularly drug delivery and photothermal chemotherapy.
J. Mater. Chem. B, 2024,12, 4785-4808
https://doi.org/10.1039/D3TB03004K
Nanomaterials in modulating tumor-associated macrophages and enhancing immunotherapy
Reprogramming anti-inflammatory macrophages into pro-inflammatory type becomes an efficient antitumor therapeutic approach. With the development of nanotechnology, the strategy of using nanomaterials is an effective option for TAM repolarization.
J. Mater. Chem. B, 2024,12, 4809-4823
https://doi.org/10.1039/D4TB00230J
Biological applications of lipoic acid-based polymers: an old material with new promise
This review highlights the ring-opening polymerization strategies of LA molecules and recent biomedical applications of PLA while discussing the challenges they face and future perspectives.
J. Mater. Chem. B, 2024,12, 4574-4583
https://doi.org/10.1039/D4TB00581C
Application of 3D, 4D, 5D, and 6D bioprinting in cancer research: what does the future look like?
Recent advancements pertaining to the application of 3D, 4D, 5D, and 6D bioprinting in cancer research are discussed, focusing on important challenges and future perspectives.
J. Mater. Chem. B, 2024,12, 4584-4612
https://doi.org/10.1039/D4TB00310A
Amyloid detection in neurodegenerative diseases using MOFs
The adaptability of MOFs allows precise detection and quantification of amyloid proteins. This study delves into how MOFs contribute to detecting amyloid diseases, sorting their uses according to different sensing methods.
J. Mater. Chem. B, 2024,12, 4553-4573
https://doi.org/10.1039/D4TB00373J
About this collection
This collection contains recent Review-type articles published by Journal of Materials Chemistry B, the home for high impact applications, properties and synthesis of exciting new materials for biology and medicine. New articles will be added to this collection as soon as possible after publication.