Palladium/copper bimetallic system-catalyzed cascade cyclization of N-allyl ynamides and o-haloanilines: access to multifunctional benzimidazoles

Yi-Yun Zhang, Xu-Heng Yang, Ai-Ming Wen, Fang Wang, Jian Huang, Jianfang Wang and Cheng-an Tao

Org. Chem. Front., 2026
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Periodic acid-promoted methylenation of imidazoheteroarenes: a green approach using ethylene glycol as a C1 source

Marcelo S. Franco, Matheus Y. G. Watanabe, Jhefferson S. Guilhermi, Brunno S. Souza, Sumbal Saba, Jamal Rafique and Antonio L. Braga

RSC Adv., 2026, 16, 11937
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Multifunctional N-substituted 2-pyridylbenzothiazole derivatives: singlet oxygen generation, protein binding, and photoactivated anticancer and antibacterial activities

Hanan A. Mohamed, Ayman A. Abdel-Shafi, Hideyuki Miyatake, Mohamed E. El-Khouly and Amr A. Nassrallah

RSC Adv., 2025, 15, 44649
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Synthesis of benzimidazoles from o-phenylenediamines with α-keto acids via amino acid catalysis

Zhenbiao Luo, Mulin Huang, Xiangyong Wang, Xinye Wang, Zhihui Hu, Liang Zhao and Ting Huang

RSC Adv., 2025, 15, 36803
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The recent advances in benzimidazole-based antimicrobials and antitubercular agents

Abdalrahman Tarek, Maiy Y. Jaballah, Eman Z. Elrazaz and Nermin Samir

Futur J Pharm Sci, 2025, 11
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Integrating kinetic mechanism of novel benzimidazole derivatives as potential acetylcholinesterase inhibitors: Insight into in-vitro and in-silico approaches

Moh Tariq, Rafaqat Hussain, Asma Sardar, Fazal Rahim, Shoaib Khan, Umair Umer, Wajid Rehman, Yousaf Khan, Tayyiaba Iqbal, Hina Sarfraz, Mohammad Shahidul Islam and Ahmed Mohamed Tawfeek

Journal of Molecular Structure, 2025, 1348, 143418
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A novel calcium@4-benzamidobenzoate 1D coordination polymer: promising cost-effective heterogeneous catalyst for bio-inspired benzimidazoles synthesis

Neetu, Deepika Tanwar, Umesh Kumar and Amit Pratap Singh

Inorganic Chemistry Communications, 2026, 188, 116552
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Benzimidazole–Pyrimidine Hybrids: Synthesis and Medicinal Properties

Maria Marinescu and Christina Zalaru

Pharmaceuticals, 2025, 18, 1225
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Exploring the Antidiabetic Potential of Novel Benzimidazole Analogs: Synthesis, Molecular Docking and DPP-4 Activity Evaluation

Sugat Shukla, Arun Kumar, Akhalesh Kumar and Rakhi Mishra

ajc, 2025, 37, 1487
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Coumarin–benzimidazole hybrids: Design, synthesis and identification of potential anticancer agents

C.G. Arya, Neethu Mariam Thomas, Munugala Chandrakanth, Anoop Kallingal, P.G. Amrutha, M.S. Sivapriya, Ramesh Gondru and Janardhan Banothu

Bioorganic & Medicinal Chemistry Letters, 2026, 131, 130444
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Preparation and characterization of Cu (II)-porphyrin supported on Fe3O4-SiO2 (CuIIMTNCPP-SiO2-Fe3O4) in one-pot and pseudo-four-component synthesis of benzimidazole derivatives

Ameer H. Alwash, Mustafa H. Ghazi, Mahmoud S. Muter and Qais R. Lahhob

Journal of Organometallic Chemistry, 2026, 1043, 123914
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Benzimidazole-Quinoline Hybrids: Synthesis and Antimicrobial Properties

Maria Marinescu

Pharmaceuticals, 2026, 19, 180
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Synthesis and Anticancer Potential of New Benzimidazole Theranostic

Sahani Sandalima Uthumange, Muhammad Azri Faiz bin Abdul Zaki and Keng Yoon Yeong

ChemistryOpen, 2025, 14
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Integrated Experimental and DFT Studies on Green-Mediated Synthesis of 1,4-Bis(1H-benzo[d]imidazol-2-yl)benzene through Varied Solvent Systems: A Structure–Property–Activity Correlation Approach

Lalima Sharma, Siddhima Sharma, Narendra Pal Singh Chauhan, Lokesh Suthar, Neeraj Kumar and D. Vijay

Next Research, 2026, 101717
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Design, synthesis, and apoptotic antiproliferative action of new styryl benzimidazole-based derivatives as dual EGFR/BRAFV600E inhibitors

Mohamed Y. Abdel-Hady, Martha M. Morcoss, Bandar A. Alyami, Bahaa G.M. Youssif, El Shimaa M.N. Abdelhafez and Mohamed Abdel-Aziz

Journal of Molecular Structure, 2026, 1355, 144971
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MRSA inhibitory activity of new bis(benzimidazole-1,3,4-oxadiazole) hybrids linked to different spacers: Synthesis and in vitro screening

Ahmed A.M. Ahmed, Ahmed E.M. Mekky, Yasser A. El-Ossaily and Sherif M.H. Sanad

Journal of Molecular Structure, 2026, 1355, 145043
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Toxicity Assessment of Cyclic Imides and Carbofuran in the Management of Meloidogyne incognita: In Vivo and In Silico Studies

Oluwatoyin A. Fabiyi, Mariam T. Baker, Ridwan O. Alabi, Oluwakamiye I. Taiwo, Sulyman O. Ibrahim, Oyinade A. David, Hassan Ibrahim and Gabriel A. Olatunji

Chemistry & Biodiversity, 2025, 22
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Computational and experimental investigation of thiazolidinedione derivatives as PPAR-γ agonists for antidiabetic activity

Mahendra Gowdru Srinivasa, Darshan S, Sanjana Poojari, Vikyath M, Karthik G. Pujar, Prabitha Prabhakaran and Vinay C Sangamesh

Journal of Molecular Structure, 2025, 1344, 142861
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Recent Advances in Benzimidazole Chemistry: A Comprehensive Review on Synthetic Approach and Therapeutic Potential

Omar Ghazi Almohammdi, Fahad Mohammad Alminderej and Lotfi Mohamed Aroua

J Qassim Univ Sci, 2026, 5, 12
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Unveiling the potential of benzimidazoyl-based frameworks and its polymers for batteries and supercapacitors

Prashant Kaushik, Priyansha Bhargav and Ravinder Kumar

Next Research, 2025, 2, 101078
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Design, Synthesis, and Integrated In Silico–In Vitro Evaluation of Triazole‐Linked Benz/Imidazole‐2‐Thione/Selone Derivatives as Selective CDK1 Inhibitors for Breast Cancer Therapy

Alameer Ezat Abdulkareem and Ahmed Hassoon Mageed

Archiv der Pharmazie, 2025, 358
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A review on biologically important benzimidazole derivatives

Vijayabharathi Sundharaj, V. Vijayakumar and S. Sarveswari

Results in Chemistry, 2026, 21, 103042
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Computational assessment of substituted 2-Mercaptobenzimidazole Schiff bases derivatives targeting α-amylase, α-glucosidase, and PPAR-γ receptor in Type 2 Diabetes Mellitus

Vaishnavi Sanjay Patil, Sushant Prakash Kokane and Gajanan Ganesh Deshmane

Discov. Chem., 2025, 2
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Magnetic nanohybrids of folic acid as green biocatalysts for the synthesis of heterocyclic compounds

Maasoumeh Jafarpour, Abdolreza Rezaeifard, Narges Pourmorteza, Rashid Ghermezi and Fatemeh Salkhordeh

Sci Rep, 2025, 15
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Benzimidazole derivatives as anticancer agents: a comprehensive review of their synthesis, mechanism, and clinical potential

Vikrant Kumar, Purabi Saha, Ritesh Jha, Himani and Balasubramanian Narasimhan

Future Medicinal Chemistry, 2026, 18, 447
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Synthesis and In Vitro Screening of Methicillin‐Resistant Staphylococcus aureus Inhibitory Activity of New Bis(benzimidazole‐1,3,4‐oxadiazole) Hybrids Linked by Different Spacers

Ahmed A. M. Ahmed, Sherif M. H. Sanad, Yasser A. El‐Ossaily and Ahmed E. M. Mekky

ChemistrySelect, 2026, 11
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