Molecular and System-Level Characterization of MMP12 Suppression in Lung Cancer: A Combined Bioinformatics and Molecular Approach

Shriefa Almutairi, Rima Hajjo, Dima A. Sabbah, Kamal Sweidan, Zainab Ahmed Rashid and Sanaa K. Bardaweel

IJMS, 2025, 26, 11802
DOI: 10.3390/ijms262411802

Exploring the anticancer potential of nitrated N-substituted-4-hydroxy-2-quinolone-3-carboxamides: synthesis, biological assessment, and computational analysis

Reem A. Islim, Nisreen S. Hamadeh, Reema Abu Khalaf, Rima Hajjo, Sanaa K. Bardaweel, Kamal Sweidan, Aya M. Al-Zuheiri, Swapnaa Balaji, Amit K. Tiwari, Ghassan Abushaikha and Dima A. Sabbah

BMC Chemistry, 2025, 19
DOI: 10.1186/s13065-025-01616-w

Unveiling of phosphodiesterase-5 hot residues binding to xanthine derivatives for erectile dysfunction therapy: A computational drug repurposing approach

Amin O. Elzupir, Sondos A. J. Almahmoud and Muhammad Nasir Iqbal

PLoS One, 2025, 20, e0336267
DOI: 10.1371/journal.pone.0336267

Computational Studies toward the Identification of CB2R-M1R Dual Modulators

Israa H. Isawi, Rufaida Al-Zoubi, Rima Hajjo, Rayan M. Obeidat, Islam H. AlKhawaldeh, Omar M. Al Kilani, Mahmoud J. Alhaj Hasan and Paula Morales

ACS Omega, 2026, 11, 13121
DOI: 10.1021/acsomega.5c07866

Investigating the role of KARS in lung adenocarcinoma via single-cell RNA sequencing

Huafang Hu, Yan Zhong, Guangbiao Li, Ru Deng, Jingfu Lin, Wenkun Wu and Yonghong Li

Discov Onc, 2024, 15
DOI: 10.1007/s12672-024-01633-6

Phytochemical characterization and bioinformatics guided evaluation of antioxidant and cytotoxic effects of Psoralea bituminosa

Nour H. Aboalhaija, Rima Hajjo, Fatma Afifi, Heba Syaj and Rana Abu-Dahab

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-04195-x