Recent advances in nanophotosensitizers for overcoming tumor hypoxia in photodynamic therapy

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Chem. Commun., 2026, 62, 1316
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Folic acid-functionalized mesoporous silica nanoparticles integrating fluorouracil-derived carbon dots and porphyrin for targeted breast cancer chemo-photodynamic therapy

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An overview of porphyrin-comprising supramolecular scaffolds for cancer phototherapy

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Phototherapeutic antibacterial applications of porphyrin-based metal–organic frameworks

Cheng Qi, Min Chen, Zhifei Yuan, Weiqi Wang and Xiaohua Zheng

Chem. Commun., 2025, 61, 15313
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A multifunctional NIR responsive upconversion porphyrin nanoprobe for Fenton/FRET induced ROS amplification and targeted drug delivery

Antara Ghosh, Archana Singh, Subhabrata Guha, Bijay Saha, Gaurav Das and Sumanta Kumar Sahu

Journal of Colloid and Interface Science, 2025, 700, 138311
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Biomedical applications and perspectives of two-dimensional porphyrin-based MOFs

Cheng Qi, Xuanxuan Luo, Huoying Pan, Weiqi Wang and Xiaohua Zheng

Front. Pharmacol., 2026, 17
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Recent Advances in Glutathione Depletion-Enhanced Porphyrin-Based nMOFs for Photodynamic Therapy

Bin Gong, Qiuyun Zhang, Jiayi Chen, Yijie Qu, Xuanxuan Luo, Weiqi Wang and Xiaohua Zheng

Pharmaceutics, 2025, 17, 244
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Nanoscale Metal−Organic Frameworks: An Emerging Versatile Tool for Next‐Generation Photodynamic Therapy

Gopal Singh Attar, Vandana Bhalla and Manoj Kumar

Chemistry An Asian Journal, 2025, 20
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Evolution of nMOFs in photodynamic therapy: from porphyrins to chlorins and bacteriochlorins for better efficacy

Yutao Zou, Jiayi Chen, Yijie Qu, Xuanxuan Luo, Weiqi Wang and Xiaohua Zheng

Front. Pharmacol., 2025, 16
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A Porphyrin-Based Metal–Organic Framework as a Photosensitizer for Singlet Oxygen Generation and Photocatalytic Water Treatment

Behrang Salahshournia, Ali Noroozi, Daniel Fortin, Lulzim Shkreta, Benoit Chabot, Armand Soldera, Hubert Cabana and Pierre D. Harvey

ACS Appl. Opt. Mater., 2025, 3, 1254
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Activatable chemiluminescence enabled external-light-free photodynamic therapy: From mechanisms, structural designs to theranostics

Yan-Qin He and Jian-Hong Tang

Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 2025, 65, 100724
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Precise delivery and controlled release: strategies and advances in TLR7/8 agonist prodrugs for cancer immunotherapy

Yutao Zou, Ting Li, Huoying Pan, Jiangle Liu, Jingxuan He, Haoyu Ju, Weiqi Wang and Xiaohua Zheng

Front. Immunol., 2026, 17
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Metal-organic frameworks-loaded indocyanine green for enhanced phototherapy: a comprehensive review

Yutao Zou, Qiuyun Zhang, Jiayi Chen, Weiqi Wang and Xiaohua Zheng

Front. Bioeng. Biotechnol., 2025, 13
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Facile Preparation of Nanoscale Chlorin-Integrated Covalent Organic Frameworks for Combined Chemophototherapy

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Hyaluronic acid coated GSH-responsive Mn(III)-pMOF-based nanosonosensitizers for cascade-catalytic enhancement of sonodynamic therapy against hepatocellular carcinoma

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International Journal of Biological Macromolecules, 2025, 318, 145269
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Recent Advances in Porphyrin-Based Covalent Organic Frameworks for Synergistic Photodynamic and Photothermal Therapy

Cheng Qi, Jiayi Chen, Yijie Qu, Xuanxuan Luo, Weiqi Wang and Xiaohua Zheng

Pharmaceutics, 2024, 16, 1625
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Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment

Zainab Lafi, Sina Matalqah, Ebaa Abu-Saleem, Nisreen Asha, Hala Mhaidat, Sherine Asha, Lara Al-Nashash and Hussein S. Janabi

Med Oncol, 2024, 42
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Nanoengineering of Porphyrin‐Based Biomaterials for Innovative Cancer Therapy

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The Chemical Record, 2026
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Hybrid-Ligand Metal–Organic Frameworks Enabling Radio–Radiodynamic–Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors

Shiyi Zhai, Zhu You, Jiangsheng Li, Benchao Zheng, Xiaoyu Zhao, Wenyan Jiang, Danning Su, Hongbo Wang, Chuanhui Han and Kuangda Lu

ACS Nano, 2025, 19, 30100
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Targeted photodynamic therapy: enhancing efficacy through specific organelle engagement

Jiawen Tao, Zhifei Yuan and Mengjiao Zhou

Front. Pharmacol., 2025, 16
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Nanoscale Porphyrin-Based Metal–Organic Frameworks for Enhanced Radiotherapy–Radiodynamic Therapy: A Comprehensive Review

Bin Gong, Qiuyun Zhang, Yijie Qu, Xiaohua Zheng and Weiqi Wang

Pharmaceutics, 2025, 17, 883
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Application of Hypoxia-Activated Prodrugs in Tumor Therapy: Design Strategies and Perspectives

Shengyu Liu, Mijia Zhang, Xiangxi Sun, Peng Wang, Guogang Zhang and Wenyan Li

J. Med. Chem., 2025, 68, 22055
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Metal–Organic Frameworks Against Tumor Metastasis: Therapeutic Targets, Strategies, and Challenges for Clinical Translation

Jiahui Wang, Xiuxiu Qiu, Ruoyu Wang, Beibei Hong, Hegen Li and Zhanxia Zhang

Cancer Medicine, 2025, 14
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Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems: Developments and perspectives

Jaqueline F. de Souza, Siara Silvestri, Paulo R. de Souza, André R. Fajardo and Bernardo A. Iglesias

International Journal of Pharmaceutics, 2026, 690, 126544
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Hypoxia-activated prodrugs in cancer therapy: Medicinal chemistry, mechanisms, and precision therapeutic strategies

Anushka Rathore, Sapna Saini, Neeraja Suresh, Sweta Singh and Pragya Upadhyay

Indian Journal of Precision Medicine and Molecular Medicine, 2025, 1, 69
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Advancing biomedical technology through multifunctional porphyrin-based MOFs: design principles, applications, and biosafety evaluations

Tushuai Li, Wenxue Sun, Hongying Pan, Qi Tang, Lanxin Geng, Jin Liu, Guangfu Liao and Yanhua Zhang

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Recent advances in mitochondria-targeted porphyrin-based metal-organic frameworks for enhanced cancer therapy

Jiawen Tao, Zhifei Yuan and Mengjiao Zhou

Front. Pharmacol., 2026, 17
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Covalent organic frameworks for cancer immunotherapy: mechanisms, applications, and prospects

Yutao Zou, Min Chen, Jiayi Chen, Weiqi Wang and Xiaohua Zheng

Front. Immunol., 2026, 16
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Recent advances in cell membrane-coated porphyrin-based nanoscale MOFs for enhanced photodynamic therapy

Yutao Zou, Junjie Wu, Qiuyun Zhang, Jiayi Chen, Xuanxuan Luo, Yijie Qu, Rui Xia, Weiqi Wang and Xiaohua Zheng

Front. Pharmacol., 2024, 15
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