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Natural products inhibit inflammatory diseases by regulating macrophage polarization

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A Functional Switch Between Asperfumene and Fusicoccadiene Synthase and Entrance to Asperfumene Biosynthesis through a Vicinal Deprotonation‐Reprotonation Process

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In-situ microextractive adsorption of α-pinene from fermentation broths by a recombinant yeast

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Biosynthesis of (−)‐Vinigrol

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Biosynthesis of Edible Terpenoids: Hosts and Applications

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Towards engineering agaricomycete fungi for terpenoid production

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Unveiling the Chemical Composition and Biofunctionality of Hericium spp. Fungi: A Comprehensive Overview

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Genome Mining of the Marine-Derived Fungus Trichoderma erinaceum F1-1 Unearths Bergamotene-Type Sesquiterpenoids

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Ein funktioneller Wechsel zwischen Asperfumen‐ und Fusicoccadien‐Synthase und Eintritt in die Asperfumen‐Biosynthese durch einen vicinalen Deprotonierungs‐Reprotonierungsprozess

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Regiodivergent Photocatalytic Annulation for the Synthesis of gem‐Difluorinated Cyclic Hydrocarbons

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Regiodivergent Photocatalytic Annulation for the Synthesis of gem‐Difluorinated Cyclic Hydrocarbons

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Hidden handshakes and hostilities: the two sides of fungal metabolites in plant-fungal interactions

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Genome Mining and Biosynthesis of Fungal Africane-Type Sesquiterpenes

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Mechanistic Perspective on C–N and C–S Bond Construction Catalyzed by Cytochrome P450 Enzymes

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Intermittent blue light-dark cycles: A new strategy for enhancing triterpenoid production in medicinal Sanghuangporus vaninii

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Metabolomic analysis reveals the positive effects of Rhizopus oryzae fermentation on the nutritional and functional constituents of adlay millet seeds

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Genome Mining and Heterologous Expression-Guided Discovery of Mangicol Sesterterpenoids with Antimicrobial and Antineuroinflammatory Activities

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Metabolic reprogramming of abscisic acid-producing strain Botrytis cinerea TB-31 toward terpenoid biosynthesis using a CRISPR/Cas9 ribonucleoprotein system

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Functional Characterization of Sesquiterpene Synthases and P450 Enzymes in Flammulina velutipes for Biosynthesis of Spiro [4.5] Decane Terpene

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Integrative Transcriptome and Metabolome Analysis Reveals Candidate Genes Related to Terpenoid Synthesis in Amylostereum areolatum (Russulales: Amylostereaceae)

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Chamilactones A and B, Sesquiterpenes from the Endophytic Fungus Chaetomium nigricolor F5

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Genomic and Multi-Omics Analysis of Phlebopus portentosus: Effects of Cultivation on Secondary Metabolites

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Coculture of Coastal Macroalga-Epiphytic Trichoderma Fungi for Microalgal Algicide Production Highlighted by an Iodinated Terpenoid

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Identification of three novel P450 enzymes involved in the oxidative modification of a newly discovered fusicoccane diterpene

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Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis in Inonotus glomeratus

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Identification of Key Post‐modification Enzymes Involved in the Biosynthesis of Lanostane‐type Triterpenoids in the Medicinal Mushroom Antrodia camphorata.

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Research Progress on the Regulation and Developmental Utilization of Bioactive Metabolites Synthesis in Floccularia luteovirens

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Identification of a terpene synthase arsenal using long-read sequencing and genome assembly of Aspergillus wentii

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A Novel Sesquiterpene Synthase from Neophaeococcomyces mojaviensis for α-Santalene Production

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Structural characterization and biological activities of specialized metabolites from mangrove-derived fungi Aspergillus sp.

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Biosynthesis of the Sesquiterpenoid Malfilanol D in Aspergillus ustus Implies Alkyl and Hydride Migrations during the Bicyclo[5.4.0]undecane Skeleton Formation

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Activation of diterpene hydrocarbon skeletons by microbial natural P450 oxidases

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Green Synthesis and Catalysis, 2025
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Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

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Angew Chem Int Ed, 2025, 64
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Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

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Multidimensional regulation of transcription factors: decoding the comprehensive signals of plant secondary metabolism

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A Unique CYP450 Enzyme Unlocks Antrodia Camphorata Lanostane Triterpenoid Diversity Through Oxidation and Skeletal Rearrangement

Shungang Jiao, Wentao Sun and Youcai Hu

Angewandte Chemie, 2026, 138
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Recent advances in chemistry and bioactivity of decalin-containing natural products (2014–2025)

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Mutations in Aristolochene Synthase Promote Hydroxylation of Aristolochene in Aspergillus oryzae

Thirat Anumon and Pakorn Wattana‐Amorn

Chemistry & Biodiversity, 2025, 22
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Applications of cytochrome P450 monooxygenases in the biosynthesis of active pharmaceutical ingredients

Yuben Qiao, Xiaodong Zhang, Qianqian Xu, Ikuro Abe and Aitao Li

Green Synthesis and Catalysis, 2025
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A new sesquiterpene with a specialized [4,4] bicyclononane skeleton from the marine-derived fungus Metarhizium sp. P2100

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Genome Mining Reveals a UbiA-Type Prenyltransferase Access to Farnesylation of Diketopiperazines

Xiaotian Yu, Chuanteng Ma, Wenxue Wang, Jing Ge, Zian Wang, Jiaqi Lin, Qian Che, Guojian Zhang, Tianjiao Zhu and Dehai Li

Org. Lett., 2024, 26, 3349
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Biosynthesis of (−)‐Vinigrol

Run Xu and Yi Zou

Angew Chem Int Ed, 2025, 64
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Synergistic acetyl-CoA augmentation strategy (SATS) for improved terpenoid biosynthesis in Saccharomyces cerevisiae

Yiying Huo, Pan Feng, Haoran Bi, Kai Wang, Yang Zhang, Yunming Fang, Meng Wang and Tianwei Tan

Biochemical Engineering Journal, 2025, 213, 109572
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Cloning and functional characterization of sesquiterpene synthase genes from Inonotus obliquus using a Saccharomyces cerevisiae expression system

Qiao Liu, Junzhi Peng, Ziling Tao, Jiluan Zhang, Weifan Wu, Zhiwu Tan, Tao Zhou, Xiaoying Cao and Jihong Jiang

World J Microbiol Biotechnol, 2025, 41
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Identification of two novel sesterterpene skeletons offers the first experimental evidence for the cyclization mechanism of mangicdiene synthase

Pan Luo, Jian-Ming Lv, Hong-Ting Zhen, Ying-Qi Zhao, Jing-Yuan Liu, Jin-Yu Hong, Shao-Yang Li, Gao-Qian Wang, Guo-Dong Chen, Shui-Xing Zhang, Dan Hu and Hao Gao

Chinese Chemical Letters, 2026, 37, 111042
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Identification of Key Post‐modification Enzymes Involved in the Biosynthesis of Lanostane‐type Triterpenoids in the Medicinal Mushroom Antrodia camphorata.

Ya‐Qun Zhang, Meng Zhang, Zi‐Long Wang, Yang‐Oujie Bao, Yu‐Qi Wang, Yun‐Gang Tian, Lei Ye and Min Ye

Angewandte Chemie, 2025, 137
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