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Nanotechnologies for traditional Chinese medicine research: quality control and therapeutic applications

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Traditional Chinese medicine as a promising choice for future control of PEDV

Conghao Ji, Shuxuan Li, Cunhai Hu, Tongtong Liu, Qingqing Huang, Mengyuan Yang, Mengxin Yang, Qianqian Wang, Aifang Li, Dandan Guo, Yu Huang, Sugai Yin and Shuying Feng

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Advancements in herbal medicine-based nanozymes for biomedical applications

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Chinese Medical Journal, 2025, 138, 1037
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Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

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De novo engineering of nanoformulation from traditional Chinese medicine mixtures for psoriasis

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Herbal Medicine-Derived Exosome-Like Nanovesicles: A Rising Star in Cancer Therapy

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Advanced Application of Polymer Nanocarriers in Delivery of Active Ingredients from Traditional Chinese Medicines

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Enhancing flavonoid enrichment via supramolecular: A study on the material basis of Sanguisorbae radix after carbonizing by stir-frying

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Nature Herbal Medicine‐ Tissue Engineering Strategies for Regulate Cell Homeostasis in Bone Regeneration

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Research progress on nanotechnology of traditional Chinese medicine to enhance the therapeutic effect of osteoarthritis

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Mechanism and research progress of improving cartilage injury based on the combination of active ingredients in traditional Chinese medicine and biomaterials

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Exploiting the nanotechnological approaches for traditional Chinese medicine in childhood rhinitis: A review of future perspectives

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Traditional Chinese medicine targets on hepatic stellate cells for the treatment of hepatic fibrosis: A mechanistic review

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PANoptosis: a potential target of cardiomyopathy

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Nanocarrier-Based Delivery of Arsenic Trioxide for Hepatocellular Carcinoma Therapy

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Collision of Chinese medicine and materials science: Interdisciplinary biomaterials’ perspectives

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Integrating HPLC Fingerprinting, Gray Relational Analysis, and In Vitro–In Vivo Evaluation of Xiaochaihu Decoction and Its Nano‐Phase

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A comprehensive overview of triptolide utilizing nanotechnology and its potential applications in prostate diseases

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Plant-derived secondary metabolites and nanotechnology: innovative strategies and emerging challenges in myocardial ischemia-reperfusion injury therapy

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Traditional Chinese Medicine-Based Nanoformulations for Enhanced Photothermal Therapy of Cancer

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Molecular signaling pathways in doxorubicin-induced nephrotoxicity and potential therapeutic agents

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Therapeutic and prophylactic effects of baicalin on Pneumocystis infection in immunosuppressed rats

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Nano-formulated delivery of active ingredients from traditional Chinese herbal medicines for cancer immunotherapy

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Effects of nano-Rhodiola rosea combined with treadmill exercise on anti-exercise fatigue in rats

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Application of Pharmaceutical Nanotechnologies for Chinese Herbal Medicines in the Treatment of Pulmonary Diseases and Lung Cancer

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IJN, 2025, Volume 20, 10567
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Targeting ferroptosis unveils a new era for traditional Chinese medicine: a scientific metrology study

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YiQiWenShen formula ameliorates myasthenia gravis through T follicular helper cells/T follicular regulatory cells immune rebalancing

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Mogroside V reduced the excessive endoplasmic reticulum stress and mitigated the Ulcerative colitis induced by dextran sulfate sodium in mice

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Current landscape of dyslipidemia-related randomized clinical trials registered on the International Clinical Trials Registry Platform

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Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis

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Clinical Efficacy of Endoscopic Retrograde Cholangiopancreatography Combined With Traditional Chinese Medicine Comprehensive Nursing in the Treatment of Biliary Tract Complications After Liver Transplantation

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Advances in natural product-based nanoparticles for the treatment of acute lung injury

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Nanoliposomes Encapsulated Rapamycin/Resveratrol to Induce Apoptosis and Ferroptosis for Enhanced Colorectal Cancer Therapy

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Acidic Environment-Responsive Metal Organic Framework-Mediated Dihydroartemisinin Delivery for Triggering Production of Reactive Oxygen Species in Drug-Resistant Lung Cancer

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Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng

Ying Yu, Li Yun Wang, Yan Chi Liu, Hao Cui, Cheng Yuan and Cheng Xiao Wang

Pharm Res, 2024, 41, 513
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Therapeutic potential of traditional Chinese medicine loaded nanocarriers in wound management: Current status and their future perspective

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Traditional Chinese Medicine Formulae QY305 Reducing Cutaneous Adverse Reaction and Diarrhea by its Nanostructure

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Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia

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Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

Chong Qiu, Jun Zhe Zhang, Bo Wu, Cheng Chao Xu, Huan Huan Pang, Qing Chao Tu, Yu Qian Lu, Qiu Yan Guo, Fei Xia and Ji Gang Wang

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Novel nano-drug delivery system for natural products and their application

Li Huang, Xue-Hua Huang, Xi Yang, Jia-Qin Hu, Yi-Zhun Zhu, Pei-Yu Yan and Ying Xie

Pharmacological Research, 2024, 201, 107100
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Prevention and treatment of radiation injury by traditional Chinese medicine: A review

Lixue He, Shixing Edi, Jun Ma, Zilin Kong, Chunguang Dai, Linfang Huang, Rui Zeng and Kaijun Gou

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Panax notoginseng saponins and acetylsalicylic acid co-delivered liposomes for targeted treatment of ischemic stroke

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International Journal of Pharmaceutics, 2024, 667, 124782
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Nanotherapeutic derived from multiple bioactive ingredients of natural products: A robust tool for the development of traditional medicine

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Research progress on nanoplatforms based delivery of traditional Chinese medicine against multi-drug resistance in breast cancer

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Research progress of traditional Chinese medicine as sensitizer in reversing chemoresistance of colorectal cancer

Xiang Lin, Xinyu Yang, Yushang Yang, Hangbin Zhang and Xuan Huang

Front. Oncol., 2023, 13
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An enhanced cardio-protective effect of nanoparticles loaded with active components from Polygonum orientale L. against isoproterenol-induced myocardial ischemia in rats

Jincheng Jing, Shumei Fang, Yueting Li, Wenting Liu, Cong Wang, Yanyu Lan, Yonglin Wang and Chang Yang

International Journal of Pharmaceutics, 2024, 655, 124047
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Curcumin for inflammatory bowel disease therapy: advances in mechanisms, clinical applications, and drug delivery

Zilong Zhang, Chao Ding, Haonan Xu, Fujiang Guo, Yiming Li, Dongdong Zhang and Rui Wang

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Smart Targeted Delivery Systems for Enhancing Antitumor Therapy of Active Ingredients in Traditional Chinese Medicine

Chenglong Kang, Jianwen Wang, Ruotong Li, Jianing Gong, Kuanrong Wang, Yuxin Wang, Zhenghua Wang, Ruzhe He and Fengyun Li

Molecules, 2023, 28, 5955
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Design, Synthesis, Formulation, and Bioevaluation of Trisubstituted Triazines as Highly Selective mTOR Inhibitors for the Treatment of Human Breast Cancer

Qiwen Sun, Yuxiu Chu, Nana Zhang, Rui Chen, Lili Wang, Jiangxia Wu, Yongxi Dong, Hongliang Li, Ling Wang, Lei Tang, Changyou Zhan and Ji-Quan Zhang

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Nanoparticle Delivery of Active Traditional Chinese Medicine Ingredients: A New Strategy for the Treatment of Liver Cancer

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A Powerful Tool in the Treatment of Myocardial Ischemia-Reperfusion Injury: Natural and Nanoscale Modified Small Extracellular Vesicles Derived from Mesenchymal Stem Cells

Zhou Zhou, Xuan Zhang, Shuai Wang, Xianliang Wang and Jingyuan Mao

IJN, 2023, Volume 18, 8099
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Therapeutic translation of traditional Chinese medicine Huangqi derived exosome like nanoparticles: targeting prostate cancer through ferroptosis activation, immune reprogramming, and microbiome modulation

Ye An, Jin-Zhou Xu, Gui-Chen Ye, Jian-Xuan Sun, Jia-Cheng Xiang, Chen Gong, Si-Han Zhang, Lin-Tao Miao, Si-Yang Ma, Ming-Xia Ding, Shao-Gang Wang and Qi-Dong Xia

J Nanobiotechnol, 2026
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Nanocarriers based therapy and diagnosis of brain diseases: cross the blood-brain barrier

Lijun An, Jinwei Zhang, Xiaobo Wang, Yuanyuan Ge, Kunhui Sun, Junlin Dong, Ping Wang, Wei Li, Meifang Li, Xuelei Hu, Bing Wang and Xie-An Yu

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Emerging role of Saikosaponin A in tumor therapy and tumor microenvironment immunomodulation

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Biomedicine & Pharmacotherapy, 2026, 195, 119000
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Mitophagy and Mitochondrial Function Regulation by Traditional Chinese Medicine Small Molecules in Cancer Therapy: Mechanisms, Challenges, and Translational Opportunities

Zixuan Shi, Lipeng Wang, Zifan Wang, Yifei Ma, Erling Li, Peirong Xu, Tianli Fan and Guiqin Hou

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Preparation of aripiprazole-poly(methyl vinyl ether-co-maleic anhydride) nanocomposites via supercritical antisolvent process for improved antidepression therapy

Lin-Fei Chen, Ying Chen, You-Yu Duan, Man-Man Zhang, Pei-Yao Xu, Ranjith Kumar Kankala, Shi-Bin Wang and Ai-Zheng Chen

Regenerative Biomaterials, 2022, 9
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Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles

Fei Shen, Yun-Sheng Zheng, Lan Dong, Ziyang Cao and Jie Cao

Front. Pharmacol., 2024, 15
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Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies

Ling YANG, Yani WANG, Xietao YE, Qiaoming LIU, Ding QU and Yan CHEN

Chinese Journal of Natural Medicines, 2024, 22, 1177
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Formation of a traditional Chinese medicine self-assembly nanostrategy and its application in cancer: a promising treatment

Ju Huang, Yu Zhu, Hang Xiao, Jingwen Liu, Songtao Li, Qiao Zheng, Jianyuan Tang and Xiangrui Meng

Chin Med, 2023, 18
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Hyaluronic acid application strategies for plant bioactive component delivery: A review

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International Journal of Biological Macromolecules, 2024, 282, 137129
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Self‐Assembled Dictamni Cortex Nanoparticles Ameliorate Psoriasis by Epigenetic Modulation of HSP90AB1 and Suppression of the Inflammatory Response

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Nanoparticle-based Traditional Chinese Medicine for Immunotherapy in Gastrointestinal Tumors

Linjia Peng, Yanfeng Liang, Qiuli Zhang, Xiaonan Guo, Zixuan Gao and Daxiang Cui

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Application of Composite Biomaterials from Chinese Herbal Medicine in the Field of Bone Tissue Engineering

Liqing Ke, Wenxiang Cheng and Peng Zhang

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Exploiting Nanotechnology for Drug Delivery: Advancing the Anti-Cancer Effects of Autophagy-Modulating Compounds in Traditional Chinese Medicine

Zixian Liu, Tianming Lu, Ruoning Qian, Zian Wang, Ruogu Qi and Zhengguang Zhang

IJN, 2024, Volume 19, 2507
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Functionalized biomimetic nanoparticles loaded with salvianolic acid B for synergistic targeted triple-negative breast cancer treatment

Nuo Cheng, Qianqian Zhou, Zongfang Jia, Yang Mu, Sheng Zhang, Lei Wang and Yunna Chen

Materials Today Bio, 2025, 30, 101441
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Development of modern Chinese medicine guided by molecular compatibility theory

Lifeng Luo, Jieru Zhou, Xiaonan Liu, Yanyu Chen, Xiao Du, Lili Gao, Yunting Sun and Shuling Wang

Journal of Advanced Research, 2025, 73, 713
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Targeting lipophagy and nuclear receptors in metabolic-associated fatty liver disease: insights from traditional Chinese medicine

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Front. Pharmacol., 2026, 16
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The role of plant-derived extracellular vesicles in ameliorating chronic diseases

Ashwani Tiwari, Naveen Soni, Shweta Dongre, Megha Chaudhary and Bhawana Bissa

Mol Biol Rep, 2025, 52
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Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting

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Sci Rep, 2025, 15
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Unlocking the Medicinal Potential of Plant-Derived Extracellular Vesicles: current Progress and Future Perspectives

Xiaoliang Liu, Kecheng Lou, Yunmeng Zhang, Chuanxiao Li, Shenghong Wei and Shangzhi Feng

IJN, 2024, Volume 19, 4877
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Use of traditional Chinese medicine bezoars and bezoar-containing preparations in hepatocarcinoma

De-Hui Li, Qian-Er Wen, Rui-Qi Feng, Chang Qiao and Xiao-Tong Tian

World J Gastrointest Oncol, 2024, 16, 4770
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Luteolin and glycyrrhetinic exert cooperative effect on liver cancer by selfassembling into carrier-free nanostructures

Lanlan Zong, Yuxin Dai, Jiahao Xu, Chaofeng Qiao, Yao Qi, Chengyuan Ma, Hong Li, Xiaobin Pang and Xiaohui Pu

Chinese Chemical Letters, 2025, 36, 111325
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Network pharmacology-guided self-assembling quercetin hydrogel from A. membranaceous accelerates diabetic wound healing

Meixuan Liu, Hanlei Zhou, Jialiang Wang, Yirang Wang, Chenghao Cai, Chunmao Han, Lina Dong and Xingang Wang

Phytomedicine, 2026, 158137
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Carrier-free Chinese herbal small molecules self-assembly with 3D-porous crystal framework as a synergistic anti-AD agent

Rui Shen, Yuhong Chen, Xiangyu Li, Xi Wang, Aihong Yang and Xiaodi Kou

International Journal of Pharmaceutics, 2023, 630, 122458
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Modified ZIF-8 Nanoparticles for Targeted Metabolic Treatment of Acute Spinal Cord Injury

Sen Lin, Jingwen Cui, Xiang Li, Shurui Chen, Kai Gao and Xifan Mei

ACS Appl. Mater. Interfaces, 2024, 16, 14503
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Self-Assembly of Rhein and Matrine Nanoparticles for Enhanced Wound Healing

Xunxun Wu, Ranqing Zang, Yiting Qiu, Ni Yang, Meiyan Liu, Site Wei, Xianxiang Xu and Yong Diao

Molecules, 2024, 29, 3326
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Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023

Sinan Ai, Yake Li, Huijuan Zheng, Meiling Zhang, Jiayin Tao, Weijing Liu, Liang Peng, Zhen Wang and Yaoxian Wang

J Nanobiotechnol, 2024, 22
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Black Phosphorus Nanosheet-Loaded Traditional Chinese Medicine Curcumin for Acute Rhinosinusitis Therapy and Its Mechanism

Yongze Liu, Lei He, Dingding Liu, Xuefeng Jiang, Feng Chen, Xiaofeng Ma, Saijie Song, Jun Zhang, Jian Shen and Xia Gao

ACS Appl. Nano Mater., 2024, 7, 17239
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Lithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage

Yu Zhang, Qiqi Lou, Hao Lian, Ran Yang, Ruolin Cui, Leyang Wang, Bitao Ma, Lingli Hou, Lilun Jin and Weiran Teng

Materials Today Bio, 2025, 31, 101589
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Study on the Nanoaggregate Formation Mechanism and Antipyretic Effect of Maxing Shigan Decoction

Bingbing Zhao, Yanxu Zhang, Zhengmin Fan, Ziwei Lin, Lihong Wang, Hongteng Li, Haojie Zhen and Chunli Wu

ACS Omega, 2024, 9, 19311
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Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

Hao Zheng, Yiquan Chen, Wei Luo, Shiqi Han, Mengjuan Sun, Min Lin, Chenghan Wu, Lili Gao, Tian Xie and Na Kong

J Nanobiotechnol, 2025, 23
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